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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Phenergan Injection 2 ml

Phenergan Injection 2 ml belongs to the class of drugs called antihistamines used to prevent or treat symptoms of allergic conditions such as hay fever (seasonal allergies), allergic skin reactions such as itching or hives (itchy, raised bumps on the skin), allergic conjunctivitis (redness and irritation in the membrane that covers the eye) and other types of allergy. Also, it is used to prevent and treat nausea and vomiting after surgery due to certain types of anaesthesia and motion sickness. Additionally, Phenergan Injection 2 ml is used in postoperative, preoperative and obstetric (during labour) sedation. An allergy occurs when foreign elements, known as allergens, attack and invade our body, thereby causing the release of histamine (a chemical messenger) that causes swelling, inflammation, redness, itchiness, and watery nose and eyes.

Phenergan Injection 2 ml contains Promethazine, an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Also, it blocks the histamine receptors in the vomiting centre in the brain and prevents nausea and vomiting. Additionally, Promethazine possesses sedative effects and helps you feel relaxed before and after surgery. 

Phenergan Injection 2 ml will be administered by a healthcare professional; do not self-administer. Phenergan Injection 2 ml may cause common side effects such as drowsiness, dizziness, tiredness, incoordination, lack of energy, increased blood pressure or occasional low blood pressure. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Promethazine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before receiving Phenergan Injection 2 ml. Phenergan Injection 2 ml is not recommended for use in children below two years of age and in dehydrated children. Avoid alcohol consumption while receiving Phenergan Injection 2 ml as it may increase drowsiness and decrease mental alertness. Avoid driving if you experience any side effects that impair your physical or mental abilities after receiving Phenergan Injection 2 ml. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Abbott Healthcare Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Phenergan Injection 2 ml

Allergic symptoms, nausea and vomiting

Medicinal Benefits

Phenergan Injection 2 ml contains Promethazine, an antihistamine (anti-allergic drug) used to prevent or treat symptoms of allergic conditions such as hay fever (seasonal allergies), allergic skin reactions such as itching or hives (itchy, raised bumps on the skin), allergic conjunctivitis (redness and irritation in the membrane covering the eye) and other types of allergy. It blocks the action of histamine, a substance responsible for causing allergic reactions. Thereby, it helps to provide relief from symptoms of allergy. Also, it blocks the histamine receptors in the vomiting centre in the brain and prevents nausea and vomiting after surgery due to certain types of anaesthesia and motion sickness. Additionally, Promethazine possesses sedative effects and helps you feel relaxed before and after surgery. Thus, it is used in postoperative, preoperative and obstetric (during labour) sedation. Phenergan Injection 2 ml may be used to treat a symptom of Parkinson’s disease known as oculogyric crises (uncontrolled rolling of eyeballs).

Side Effects of Phenergan Injection 2 ml

  • Drowsiness
  • Dizziness
  • Tiredness
  • Incoordination
  • Lack of energy
  • Increased blood pressure or occasional low blood pressure

Directions for Use

Phenergan Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Promethazine or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before receiving Phenergan Injection 2 ml. Phenergan Injection 2 ml is not recommended for children below two years of age and in dehydrated children. Avoid alcohol consumption while receiving Phenergan Injection 2 ml as it may increase drowsiness and decrease mental alertness. Avoid driving if you experience any side effects that impair your physical or mental abilities after receiving Phenergan Injection 2 ml. You may be advised to postpone skin allergy tests as Phenergan Injection 2 ml may suppress the reaction to the test allergens. Phenergan Injection 2 ml may give false positive or false negative results on pregnancy tests. Also, it may interact with blood sugar tests and not yield accurate results. Therefore, before undergoing any tests, please inform your doctor or lab technician that you are on treatment with Phenergan Injection 2 ml. 

Therapeutic Class

ANTIHISTAMINE

Drug-Drug Interactions

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PromethazineRopinirole
Critical
PromethazineDronedarone
Critical

Drug-Drug Interactions

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PromethazineRopinirole
Critical
How does the drug interact with Phenergan Injection 2 ml:
When Ropinirole is taken with Phenergan Injection 2 ml, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Phenergan Injection 2 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, dizziness, and lightheadedness. Do not stop using any medications without consulting a doctor.
PromethazineDronedarone
Critical
How does the drug interact with Phenergan Injection 2 ml:
Coadministration of Phenergan Injection 2 ml and dronedarone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Dronedarone is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop taking any medications without consulting a doctor.
PromethazineMesoridazine
Critical
How does the drug interact with Phenergan Injection 2 ml:
Using Mesoridazine together with Phenergan Injection 2 ml may raise the chance of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Phenergan Injection 2 ml is not recommended, please consult your doctor before taking it. They can be taken if your doctor prescribes them. Do not stop taking any medication without consulting your doctor.
PromethazinePotassium chloride
Critical
How does the drug interact with Phenergan Injection 2 ml:
Taking Phenergan Injection 2 ml with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Potassium chloride is not recommended, as it can lead to an interaction, they can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
PromethazineCisapride
Critical
How does the drug interact with Phenergan Injection 2 ml:
Phenergan Injection 2 ml can increase the blood levels of Cisapride, which increases the risk of side effects.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Cisapride is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PromethazineThioridazine
Critical
How does the drug interact with Phenergan Injection 2 ml:
Taking Phenergan Injection 2 ml with Thioridazine can increases the risk and severity of side effects such as extreme drowsiness, confusion, agitation, vomiting, blurred vision, feeling hot or cold, sweating, muscle stiffness, fainting, seizure (fits).

How to manage the interaction:
Taking Phenergan Injection 2 ml with Thioridazine is not recommended. Please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs, fever, muscle rigidity, irregular pulse, or fast or irregular heartbeats. Do not stop taking any medications without consulting a doctor.
PromethazinePimozide
Critical
How does the drug interact with Phenergan Injection 2 ml:
Taking Phenergan Injection 2 ml with pimozide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Phenergan Injection 2 ml with pimozide is not recommended, as it can cause interaction. They can be taken together if advised by your doctor. However, contact your doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without consulting a doctor.
PromethazineSaquinavir
Critical
How does the drug interact with Phenergan Injection 2 ml:
Phenergan Injection 2 ml can make Saquinavir more potent and increase the risk of side effects.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Saquinavir is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PromethazineHalofantrine
Critical
How does the drug interact with Phenergan Injection 2 ml:
Using Halofantrine together with Phenergan Injection 2 ml may raise the chance of an irregular heart rhythm.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Halofantrine is not recommended, please consult your doctor before taking it. They can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
PromethazineMetoclopramide
Critical
How does the drug interact with Phenergan Injection 2 ml:
Coadministration of Metoclopramide with Phenergan Injection 2 ml can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Phenergan Injection 2 ml with Metoclopramide is generally avoided as it can possibly result in an interaction. They can be taken together However, consult a doctor if you experience puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • PROPRANOLOL
  • BROMOCRIPTINE
  • LEVODOPA
  • QUINIDINE

Diet & Lifestyle Advise

Allergies:

  • Regularly wash your hands with soap and water to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid consumption of alcohol with Phenergan Injection 2 ml as it may cause tiredness, drowsiness or lack of concentration.

Nausea and vomiting:

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Drink any other liquid at least 30 minutes after eating food. 
  • If the smell of the food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

Yes

Author Details

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Disease/Condition Glossary

Allergy: It occurs when foreign elements/allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamine' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever etc.

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor located in the brain known as the chemoreceptor trigger zone (CTZ) controls vomiting.

Phenergan Injection 2 ml Substitute

Substitutes safety advice
  • Avomine 25 Tablet 10's

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    6.08per tablet
  • Avimax Tablet 10's

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    4.50per tablet
  • PHENERGAN 25MG TABLET

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    4.95per tablet
  • PHENAMIN INJECTION

    by Others

    10.18per tablet
  • PROMETH 25MG TABLET

    by Others

    3.51per tablet
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