Pheniramine Maleate Injection 2 ml

Written By Veda Maddala , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Prescription drug

MRP ₹5.5

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₹0.8 Cashback (15%)

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Prescription drug

Whats That

About Pheniramine Maleate Injection 2 ml

Pheniramine Maleate Injection 2 ml belongs to the class of medicines called antihistamines used to treat allergic symptoms. An allergy occurs when foreign elements known as allergens attack and invade our body thereby causing the release of histamine (a chemical messenger) that causes swelling, inflammation, redness, itchiness, and watery nose, throat, and eyes.

Pheniramine Maleate Injection 2 ml contains Pheniramine that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It directly acts on the brain and relieves symptoms of allergies by preventing the release of histamine. It helps to provide relief from allergic symptoms.

Pheniramine Maleate Injection 2 ml will be administered by a healthcare professional; do not self-administer. Some people may experience a stinging or burning sensation at the injection site, rapid or irregular heartbeat, drowsiness, dizziness, nausea, vomiting, restlessness, dry mouth, weakness or headache. If any of these side effects persist or worsen, please consult your doctor.

If you are allergic to Pheniramine or any other ingredients and are being treated for an enlarged prostate gland or overactive thyroid, inform your doctor. Please consult a doctor before taking Pheniramine Maleate Injection 2 ml if you are pregnant or breastfeeding. Avoid taking Pheniramine Maleate Injection 2 ml if you have used monoamine oxidase inhibitors (antidepressants) in the past 14 days. Drive only if you are alert as Pheniramine Maleate Injection 2 ml may cause drowsiness. Avoid consumption of alcohol with Pheniramine Maleate Injection 2 ml as it may increase the risk of adverse effects of Pheniramine.

Uses of Pheniramine Maleate Injection 2 ml

Allergic conditions

Directions for Use

Pheniramine Maleate Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Pheniramine Maleate Injection 2 ml contains Pheniramine, an antihistamine (anti-allergic drug) used to treat symptoms of allergic conditions such as drug rashes, hay fever, serum sickness, food allergy, allergic conjunctivitis, angioneurotic oedema (swelling under the skin) and itching skin conditions. Also, it is used to treat respiratory tract conditions accompanied by increased secretion including acute rhinitis and vasomotor rhinitis. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. Thus, it helps provide relief from allergy symptoms such as sneezing/runny nose, red/itchy/watery eyes, throat swelling, itchy throat, and congestion or stiffness. Additionally, Pheniramine Maleate Injection 2 ml is used to prevent and treat motion sickness, vomiting, nausea and vertigo (spinning sensation) due to Menière’s disease (inner ear disorder) and other labyrinthine disturbances.

Storage

Keep Pheniramine Maleate Injection 2 ml out of the sight and reach of children.

Side effects of Pheniramine Maleate Injection 2 ml

Sedation

Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.

Nervousness

Here are the steps to manage medication-triggered Nervousness:

Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Feeling Agitated

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

If you are allergic to Pheniramine or any other ingredients and are being treated for an enlarged prostate gland or overactive thyroid, inform your doctor. Please consult a doctor before taking Pheniramine Maleate Injection 2 ml if you are pregnant or breastfeeding. Avoid taking Pheniramine Maleate Injection 2 ml if you have used monoamine oxidase inhibitors (antidepressants) in the past 14 days. Drive only if you are alert as Pheniramine Maleate Injection 2 ml may cause drowsiness. Avoid consumption of alcohol with Pheniramine Maleate Injection 2 ml as it may increase the risk of adverse effects of Pheniramine. You are recommended to avoid taking Pheniramine Maleate Injection 2 ml if you have lower respiratory tract diseases including asthma.

Drug-Drug Interactions

PheniramineLinezolid

Critical

PheniramineFurazolidone

Critical

Drug-Drug Interactions

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PheniramineLinezolid

Critical

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Using phenylephrine together with linezolid can increase your blood pressure.

How to manage the interaction:
Taking Pheniramine Maleate Injection 2 ml with Linezolid is not recommended but can be taken if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

PheniramineFurazolidone

Critical

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Using furazolidone together with phenylephrine can cause severe high blood pressure.

How to manage the interaction:
Taking Pheniramine Maleate Injection 2 ml with Furazolidone is not recommended, but can be taken together if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

PheniramineSelegiline

Critical

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Using Pheniramine Maleate Injection 2 ml with selageline can cause severe high blood pressure

How to manage the interaction:
Taking Pheniramine Maleate Injection 2 ml with Selegiline is not recommended, but it should be taken if prescribed by a doctor. However, if you experience headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

PheniramineDihydroergotamine

Critical

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Using dihydroergotamine together with phenylephrine may cause significant increases in blood pressure and the risk for complications may be increased.

How to manage the interaction:
Taking Pheniramine Maleate Injection 2 ml with Dihydroergotamine is not recommended but can be taken if prescribed by a doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

PheniramineErgotamine

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Using ergotamine together with Pheniramine Maleate Injection 2 ml can cause significant increase in blood pressure.

How to manage the interaction:
Although there is a interaction between Pheniramine Maleate Injection 2 ml and Ergotamine, you can take these medicines together if prescribed by your doctor. However, if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, pale or cold skin, chest pain or tightness, severe or throbbing headache, irregular heartbeat, shortness of breath, blurred vision, confusion contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

PheniramineNortriptyline

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Coadministration of Nortriptyline with Pheniramine Maleate Injection 2 ml can increase blood pressure.

How to manage the interaction:
Taking Nortriptyline with Pheniramine Maleate Injection 2 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

PheniramineDesipramine

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Taking desipramine with Pheniramine Maleate Injection 2 ml can increase the risk of irregular heartbeats.

How to manage the interaction:
Co-administration of Pheniramine Maleate Injection 2 ml with Desipramine can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

PheniramineHalothane

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Taking Pheniramine Maleate Injection 2 ml with halothane can cause irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Pheniramine Maleate Injection 2 ml and Halothane, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

PheniramineTopiramate

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Taking Pheniramine Maleate Injection 2 ml with Topiramate can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is a interaction between Pheniramine Maleate Injection 2 ml and Topiramate, but it can be taken if prescribed by a doctor. However, if you experience drowsiness, dizziness, or lightheadedness contact your doctor immediately. Do not stop using any medications without talking to your doctor.

PheniramineProcarbazine

Severe

How does the drug interact with Pheniramine Maleate Injection 2 ml Maleate Injection 2 ml:
Taking Pheniramine Maleate Injection 2 ml with procarbazine can cause severe high blood pressure

How to manage the interaction:
Although taking Pheniramine Maleate Injection 2 ml and Procarbazine together can evidently cause an interaction, but it can be taken if your doctor has suggested it. However, if you experience headache, blurred vision, confusion, seizures(fits), chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Wash your hands with soap and water regularly to prevent the spread of germs.
Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
Drink plenty of fluids to avoid dehydration.
Gargle with salt water for relief from sore throat.
Avoid consumption of alcohol with Pheniramine Maleate Injection 2 ml as it may cause tiredness, drowsiness or lack of concentration.

Side Effects of Pheniramine Maleate Injection 2 ml

Stinging or burning sensation at the injection site
Drowsiness
Dizziness
Nausea
Vomiting
Restlessness
Dry mouth
Weakness
Headache
Rapid or irregular heartbeat

Habit Forming

No

Therapeutic Class

ANTIHISTAMINE

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Pheniramine Maleate Injection 2 ml work?

Pheniramine Maleate Injection 2 ml contains Pheniramine, an anti-allergic drug that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Thus, it helps provide relief from allergy symptoms such as sneezing/runny nose, red/itchy/watery eyes, throat swelling, itchy throat, and congestion or stiffness.

Does Pheniramine Maleate Injection 2 ml cause dry mouth?

Pheniramine Maleate Injection 2 ml may cause dry mouth as a temporary side effect in some people. It is not necessary for everyone taking Pheniramine Maleate Injection 2 ml to experience this side effect. However, to avoid such side effects, drink plenty of water, regularly rinse your mouth, practice good oral hygiene and suck on sugarless candy. However, if the condition persists or worsens, please consult a doctor.

Can I take Pheniramine Maleate Injection 2 ml with phenytoin?

You are not recommended to take Pheniramine Maleate Injection 2 ml with phenytoin as co-administration of these two medicines may increase the effects of phenytoin. Therefore, please consult a doctor before taking Pheniramine Maleate Injection 2 ml with any other medicines.

Is Pheniramine Maleate Injection 2 ml safe for elderly?

Pheniramine Maleate Injection 2 ml should be used with caution in patients above 60 years of age as it may cause low blood pressure and dizziness. However, please consult a doctor before using Pheniramine Maleate Injection 2 ml.

Drug-Drug Interactions Checker List

PHENYTOIN
ATROPINE

Disease/Condition Glossary

Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamine' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever etc.