apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Phoxelon 200 Injection 1's

Phoxelon 200 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt's lymphoma, leukaemia,  neuroblastoma, retinoblastoma, adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma, small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Additionally, Phoxelon 200 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Phoxelon 200 Injection 1's contains 'Cyclophosphamide' that works by stopping or slowing the growth of cancer cells in the body. Thereby, Phoxelon 200 Injection 1's helps treat cancer. Phoxelon 200 Injection 1's suppresses the body's immune system and helps treat nephrotic syndrome.
 
In some cases, Phoxelon 200 Injection 1's may cause nausea, vomiting, stomatitis (inflamed and sore mouth), weakness, malaise (general discomfort), fever, leukopenia (low white blood cell count), and alopecia (hair loss). You are advised to talk to your doctor if the side effects persist or worsen.
 
Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. Phoxelon 200 Injection 1's may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

rxMedicinePrescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Phoxelon 200 Injection 1's

Malignant diseases (cancer), nephrotic syndrome (kidney disease)

Medicinal Benefits

Phoxelon 200 Injection 1's belongs to the group of medicines called alkylating agents used to treat malignant diseases such as Hodgkin's disease (cancer of the lymphatic system), mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma (cancer of plasma cells), Burkitt's lymphoma, leukaemia (blood cancer), neuroblastoma (cancer commonly found in the adrenal glands), retinoblastoma (eye cancer), adenocarcinoma of the ovary, mycosis fungoides, Ewing's sarcoma (cancer in and around the bones), small cell lung cancer, advanced/metastatic neuroblastoma and breast carcinoma. Phoxelon 200 Injection 1's works by stopping or slowing the growth of cancer cells in the body. Thereby, Phoxelon 200 Injection 1's helps treat cancer. Additionally, Phoxelon 200 Injection 1's is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients. Phoxelon 200 Injection 1's suppresses the body's immune system, thereby helping treat nephrotic syndrome.

Side Effects of Phoxelon 200 Injection 1's

  • Nausea
  • Vomiting
  • Stomatitis (inflamed and sore mouth)
  • Weakness
  • Malaise (general discomfort)
  • Fever
  • Leukopenia (low white blood cell count)
  • Alopecia (hair loss)

Directions for Use

Phoxelon 200 Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Phoxelon 200 Injection 1's if you are allergic to any of its components. Inform your doctor if you have acute infections, bone marrow depression, urinary tract infections, urinary outflow/obstruction, liver or kidney problems, or urinary or respiratory symptoms. Consult your doctor if you are pregnant or breastfeeding. Phoxelon 200 Injection 1's may cause myelosuppression, immunosuppression, bone marrow failure, and infections; consult your doctor if you have any concerns.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

verifiedApollotooltip
CyclophosphamideCidofovir
Critical
CyclophosphamideNalidixic acid
Critical

Drug-Drug Interactions

Login/Sign Up

CyclophosphamideCidofovir
Critical
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Phoxelon 200 Injection 1's and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CyclophosphamideNalidixic acid
Critical
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Nalidixic acid with Phoxelon 200 Injection 1's may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Phoxelon 200 Injection 1's and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
CyclophosphamideFingolimod
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Taking Fingolimod's ability to suppress the immune system may be enhanced by Phoxelon 200 Injection 1's.

How to manage the interaction:
Although taking Phoxelon 200 Injection 1's and Fingolimod together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact a doctor right away - a serious infection, problems, high body temperature, feeling cold, loose stools, a painful throat, body discomfort, difficulty breathing, losing weight, or experiencing pain or discomfort while urinating. Do not stop using any medications without a doctor's advice.
CyclophosphamideBaricitinib
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Using baricitinib together with Phoxelon 200 Injection 1's may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Phoxelon 200 Injection 1's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue the medication without consulting a doctor.
CyclophosphamideLeflunomide
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Taking Phoxelon 200 Injection 1's with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Phoxelon 200 Injection 1's can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideClozapine
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Taking Clozapine and Phoxelon 200 Injection 1's may increase the risk of infection.

How to manage the interaction:
Taking Phoxelon 200 Injection 1's with Clozapine can possibly lead to an interaction. However, they can be taken together if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideDeferiprone
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Phoxelon 200 Injection 1's and Deferiprone may increase the risk of serious and potential infections.

How to manage the interaction:
Co-administration of Phoxelon 200 Injection 1's with Deferiprone can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
CyclophosphamideLevobupivacaine
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Phoxelon 200 Injection 1's with Levobupivacaine can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levobupivacaine with Phoxelon 200 Injection 1's can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
CyclophosphamideGolimumab
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Golimumab with Phoxelon 200 Injection 1's may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Phoxelon 200 Injection 1's with Golimumab can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without a doctor's advice.
CyclophosphamideVoclosporin
Severe
How does the drug interact with Phoxelon 200 Injection 1's:
Co-administration of Phoxelon 200 Injection 1's with Voclosporin can increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Phoxelon 200 Injection 1's and Voclosporin, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. Some other signs to watch out for are feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, having a fever or chills, having diarrhea or a sore throat, feeling weak or dizzy, being confused, having trouble breathing, feeling pain or a burning sensation when you pee, or having an irregular heartbeat. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
CYCLOPHOSPHAMIDE-200MGOther diseases of blood and blood-forming organs
Severe
CYCLOPHOSPHAMIDE-200MGObstructive and reflux uropathy
Severe

Drug-Diseases Interactions

Login/Sign Up

CYCLOPHOSPHAMIDE-200MGOther diseases of blood and blood-forming organs
Severe
How does the disease interact with Phoxelon 200 Injection 1's:
Phoxelon 200 Injection 1's usage can result in severe immunosuppression, bone marrow failure, myelosuppression (leukopenia, neutropenia, thrombocytopenia, and anaemia), and myelosuppression, which can all lead to serious and occasionally deadly infections including sepsis and septic shock. During Phoxelon 200 Injection 1's treatment, complete blood counts must be closely monitored in order to determine whether the dose has to be changed. Patients should not be given Phoxelon 200 Injection 1's if their neutrophil and platelet counts are below 1,500/mm3 and 50,000/mm3, respectively.

How to manage the interaction:
Close monitoring of complete blood count is advised during treatment with Phoxelon 200 Injection 1's. Inform the doctor if you notice any signs or symptoms of bone marrow suppression such as fever, sore throat, local infection, or bleeding.
CYCLOPHOSPHAMIDE-200MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoxelon 200 Injection 1's:
Phoxelon 200 Injection 1's should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoxelon 200 Injection 1's treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoxelon 200 Injection 1's should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-200MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoxelon 200 Injection 1's:
Phoxelon 200 Injection 1's should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoxelon 200 Injection 1's treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoxelon 200 Injection 1's should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-200MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoxelon 200 Injection 1's:
Phoxelon 200 Injection 1's should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoxelon 200 Injection 1's treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoxelon 200 Injection 1's should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

Drug-Drug Interactions Checker List

  • NATALIZUMAB
  • PACLITAXEL
  • ZIDOVUDINE
  • AMIODARONE
  • AMPHOTERICIN B
  • INDOMETHACIN
  • AZATHIOPRINE
  • BUSULFAN

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your food.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Special Advise

  • Monitoring of complete blood count whilst on treatment with Phoxelon 200 Injection 1's is advised.
  • Women of childbearing potential must use highly effective contraception during treatment and for up to 1 year after the last dose.
  • Male patients who are sexually active with a female partner of child-bearing potential must use condoms during treatment and for up to 6 months after the last dose.

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner leading to the formation of tumours. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder in which the body excretes too much protein in the urine. Symptoms include foamy urine, weight gain, and swelling around the eyes and in the ankles and feet.

Phoxelon 200 Injection 1's Substitute

Substitutes safety advice
  • Cyphos 200 mg Injection 1's

    36.00per tablet
  • CYCLOCEL 200MG INJECTION

    31.50per tablet
  • Uniphos 200 Injection 1's

    36.00per tablet
  • Endoxan N 200 mg Injection 1's

    65.25per tablet
  • CYCLOXAN INJECTION 200MG

    62.10per tablet
whatsapp Floating Button

Add to Cart