Pivikto 150 mg Tablet 28's

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹39580

(Inclusive of all Taxes)

₹1979.0 Cashback (5%)

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Whats That

About Pivikto 150 mg Tablet

Pivikto 150 mg Tablet belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer.

Pivikto 150 mg Tablet contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.

To treat your condition effectually, continue using Pivikto 150 mg Tablet for as long as your doctor has prescribed it. The most common side effects include rash, decreased appetite, weight loss, nausea, mouth sores, hair loss, tiredness and weakness, vomiting, changes in certain blood tests, allergic reactions, skin reactions, high blood sugar levels, lung problems, and diarrhea. You should talk to your doctor if you persistently experience these side effects.

Avoid taking Pivikto 150 mg Tablet if you are allergic to it. It is not recommended for use in pregnancy. Lactating women do not breastfeed during treatment with Pivikto 150 mg Tablet and for one week after the last dose. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Pivikto 150 mg Tablet

Advanced or metastatic breast cancer

Directions for Use

Pivikto 150 mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Medicinal Benefits

Pivikto 150 mg Tablet contains Alpelisib, which belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.

Storage

Keep Pivikto 150 mg Tablet out of reach and sight of children.

Side effects of Pivikto 150 mg Tablet

Increased Risk Of Developing Serious Infections

Consult a doctor preferably an immunologist or a hematologist to determine the cause for the low lymphocyte count.
Maintain hygiene, including frequent hand washing, to prevent the spread of infections.
Avoid close contact with sick people to reduce the chance of infection.
A balanced diet with fruits, vegetables, whole grains, and lean proteins will support immune function.
Exercise regularly, like walking or swimming, to enhance the immune system.
When interacting with sick people or undertaking harmful activities, wear protective gear such as masks and gloves.

Decreased Levels Of Hemoglobin

Stay hydrated by taking fluids like water, juices and soups etc.
Eat fruits and vegetables which contain vitamins.
Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
Regular exercise like walking, jogging is helpful.

Increased Clotting Time

Increased Clotting Time, also known as prolonged bleeding time, is a condition in which the blood takes longer to clot, increasing the risk of excessive bleeding.
If you experience symptoms such as easy bruising, nosebleeds, or prolonged bleeding after injury or surgery, inform your doctor.
Informing your doctor about your symptoms will help them assess your condition to determine the root cause.
Certain medications, such as blood thinners or drugs that affect platelet function, can increase the risk of bleeding and prolonged clotting time.
During the assessment, your doctor will evaluate whether your medications contribute to the increased clotting time.
If your medications are found to be the cause, your doctor will review and adjust or change them to prevent further bleeding complications. This may involve stopping or reducing the dose of the offending medication or adding new medications to counteract its effects. In some cases, your doctor may prescribe additional treatments to help control bleeding and promote clotting.
A balanced diet rich in vitamin K, calcium, and omega-3 fatty acids can help support blood clotting and overall health. Foods like leafy greens, fatty fish, and fortified dairy products can be beneficial.
Your doctor will monitor your progress, adjust your treatment plan as needed, and may recommend medications or therapies to manage bleeding symptoms and promote clotting.
In severe cases, hospitalization may be necessary to manage excessive bleeding and prevent further complications.

Decreased Platelet Count

Consult a hematologist or doctor to identify the cause of thrombocytopenia (Decreased Platelet Count) and plan treatment.
Foods rich in vitamins B12, C, folate, and iron may help boost platelet count.
Avoid heavy lifting, bending, or straining to reduce bleeding risk.
Stay hydrated by drinking plenty of water to help prevent bleeding.
Avoid alcohol and tobacco to prevent lowering platelet count and reduce bleeding risk.
Regular blood tests help monitor platelet count and detect any changes.

Weight Loss

Weight loss without physical activity needs immediate medical attention.
Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
Talk to your dietician and consume food which can maintain ideal weight.

Low Calcium Levels In The Blood

Low Levels Of Potassium In The Blood

Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
Choose potassium-fortified foods such as orange juice and sports beverages.
Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
Exercise regularly, like walking or yoga, to help maintain potassium balance.
Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

Drug Warnings

It is not advised during pregnancy, nursing, or for children or young adults under 18. Before taking the Pivikto 150 mg Tablet , inform your doctor about all your medical conditions (especially lung infections, diarrhoea, diabetics, kidney or liver impairment), sensitivities or allergic conditions, and all medications you use. Consult your doctor right away if you become pregnant while taking Pivikto 150 mg Tablet . Exposure of an unborn child to this medication could cause congenital disabilities, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least one week after treatment. You should not breastfeed while taking this medication for two weeks after your last dose.

Drug-Drug Interactions

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

After your treatment begins, several dietary adjustments can help you control side effects.
Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Performing yoga may also help in improving both physical and mental health.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.
Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Side Effects of Pivikto 150 mg Tablet

Rash
Decreased appetite
Weight loss
Nausea
Mouth sores
Hair loss
Tiredness and weakness
Vomiting
Changes in certain blood tests
Severe allergic reactions
High blood sugar levels
Lung problems
Diarrhea

Habit Forming

No

Therapeutic Class

KINASE INHIBITORS

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Pivikto 150 mg Tablet works?

Pivikto 150 mg Tablet contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.

Does Pivikto 150 mg Tablet cause a change in sugar levels?

Hyperglycemia is common with Pivikto 150 mg Tablet and can be severe. Your healthcare provider will monitor your blood sugar levels before you start and during treatment with Pivikto 150 mg Tablet . Your healthcare provider may monitor your blood sugar levels more often if you have a history of Type 2 diabetes. Tell your healthcare provider right away if you develop symptoms of hyperglycemia, including excessive thirst, dry mouth, more frequent urination than usual or a higher amount of urine than normal and increased appetite with weight loss.

Is Pivikto 150 mg Tablet a traditional chemotherapy drug?

It is critical to understand that Alpelisib is not a traditional chemotherapy drug and functions in a different manner. It works by specifically targeting cancer cells and preventing their growth and spread.

What important things should I take care of while taking Pivikto 150 mg Tablet ?

While taking Pivikto 150 mg Tablet , make sure you visit your doctor at all the appointments to ensure that treatment works. Regular monitoring of blood and lipid tests and weight checks are required. An effective way of contraception should be used by both men and women while taking the Pivikto 150 mg Tablet .

Is Alpelisib a cause of infertility?

Based on findings from animal studies, Pivikto 150 mg Tablet may impair fertility in males and females of reproductive potential. Discuss the risks of taking this medication with your doctor.

Drug-Drug Interactions Checker List

APALUTAMIDE
CARBAMAZEPINE
EDOXABAN
PRIMIDONE

Special Advise

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to Pivikto 150 mg Tablet .
Pregnancy testing is recommended prior to starting treatment with Pivikto 150 mg Tablet .
Do not donate Sperm throughout treatment and at least one week after treatment.

Disease/Condition Glossary

Breast cancer: Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Metastatic breast cancer, also called stage IV breast cancer, has spread to another part of the body, most commonly the bones, lungs, brain, or liver. The process of cancer spreading is called metastasis. Metastasis happens when cancer cells break away from the original tumour in the breast and travel to other parts of the body. These cancer cells travel through the bloodstream or the lymphatic system.