Plefate 5mg Oral Suspension belongs to the group of medicines called laxatives used to treat constipation associated with piles, anal fissure, hernia, cardiovascular disorder, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, elderly and bed-ridden patients. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass. 

Plefate 5mg Oral Suspension consists of 'Sodium picosulphate' that prevents the absorption of water in the colon/intestine, thereby stimulating the propulsive (pushing forward) activity, which in turn promotes accumulation of water providing stool can pass with ease. Thus, it relieves constipation. 

You can take Plefate 5mg Oral Suspension with or without food. You are advised to take Plefate 5mg Oral Suspension for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side-effects such as diarrhoea, abdominal discomfort, pain, or cramps in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking Plefate 5mg Oral Suspension for as long as your doctor has prescribed. Drink plenty of fluids (at least 6-8 glasses) while taking Plefate 5mg Oral Suspension to prevent dehydration. Do not take Plefate 5mg Oral Suspension for more than a week as it might cause dependency on Plefate 5mg Oral Suspension for a bowel movement. Talk to your doctor if you notice any sudden changes in bowel habits that persist for over 2 weeks. Consult your doctor before taking Plefate 5mg Oral Suspension if you are pregnant or breastfeeding. Plefate 5mg Oral Suspension should not be given to children as safety and effectiveness have not been established.

Plefate 5mg Oral Suspension belongs to the group of medicines called laxatives used to treat constipation associated with piles, anal fissure, hernia, cardiovascular disorder, endoscopy, bowel clearance before radioscopy, pre/post-operative conditions, elderly and bed-ridden patients. Plefate 5mg Oral Suspension consists of Sodium picosulphate that is a stimulant laxative, prevents the absorption of water in the colonic lumen and stimulates the colon's propulsive activity, thereby promoting water accumulation

• Diarrhoea
• Abdominal discomfort, pain, or cramps

Do not take Plefate 5mg Oral Suspension if you are allergic to any of its contents; if you have/had acute abdominal surgery, intestinal obstruction, or undiagnosed abdominal pain. Drink plenty of fluids (at least 6-8 glasses) while taking Plefate 5mg Oral Suspension. Do not take Plefate 5mg Oral Suspension for more than a week as it might cause dependency on Plefate 5mg Oral Suspension for a bowel movement. Talk to your doctor if you notice any sudden changes in bowel habits that persist for over 2 weeks. Consult your doctor before taking Plefate 5mg Oral Suspension if you are pregnant or breastfeeding. Plefate 5mg Oral Suspension should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interaction: Plefate 5mg Oral Suspension may have interaction with antibiotic (tetracycline), diuretics (furosemide), and steroids (prednisolone). 

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Plefate 5mg Oral Suspension may interact with intestinal obstruction disorder, appendicitis, intestinal blockage, and bowel inflammation.
 

• TETRACYCLINE
• FUROSEMIDE
• PREDNISOLONE

• Try maintaining a balanced diet that includes fresh fruits and vegetables.
• Stay hydrated, drink enough water and fluids.
• Exercise regularly, and stay fit.
• Get enough sleep.
• Try making time to empty your bowels whenever the body tells you to.
• Eat food rich in fibre such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados). 

Include more fiber in your diet to avoid constipation and most importantly never ignore the urge to have a bowel movement.

Constipation: It refers to infrequent bowel movements. The stools are often dry, painful, and hard to pass. Constipation is a condition in which the person has fewer than three bowel movements in a week. However, bowel patterns may vary from person to person. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the normal muscle contractions in the large intestine slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fibre, not drinking enough liquids, lack of exercise, loss of tone of the bowel muscles in older people, or staying in bed for a longer duration.