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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer

Cadila Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Polycap Capsule 15's

Polycap Capsule 15's is a combination medicine used for the prevention of cardiovascular events and stroke. Polycap Capsule 15's helps in lowering of blood pressure, heart rate, lipid levels and decreases the stickiness of platelets. Heart attack or stroke occurs due to the blockage of blood flow to the heart muscle. The blockade usually occurs due to build-up of fat/cholesterol in the coronary artery. Polycap Capsule 15's lowers the risk of heart attack or stroke by controlling the blood pressure, lowering the fat and increasing HDL (good cholesterol) levels.
 
Polycap Capsule 15's contains Simvastatin (lipid-lowering agent), Ramipril (ACE inhibitor), Atenolol (beta-blocker), Aspirin (anti-platelet) and Hydrochlorothiazide (diuretic). Simvastatin helps in lowering the levels of LDL (bad) cholesterol, triglycerides and raises the levels of HDL (good) cholesterol. Ramipril relaxes the blood vessels and allows smooth blood flow. Atenolol slows down the heart rate and makes it more efficient at pumping blood. Hydrochlorothiazide helps in removal of unneeded water and salts from the body. Aspirin decreases the formation of harmful clots by preventing the platelets from sticking together. Together, Polycap Capsule 15's helps in lowering the risk of a heart attack. 
 
You are advised to take Polycap Capsule 15's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as weakness, indigestion, constipation, dizziness and musculoskeletal pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Do not take Polycap Capsule 15's if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Talk to a doctor immediately if you become pregnant while taking Polycap Capsule 15's. Consult your doctor before taking Polycap Capsule 15's if you are breastfeeding. Polycap Capsule 15's may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Polycap Capsule 15's as it could lead to increased dizziness. Polycap Capsule 15's is not recommended for children as safety and effectiveness have not been established. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side-effects/interactions.

Uses of Polycap Capsule 15's

Prevention of heart attack or stroke

Directions for Use

Swallow Polycap Capsule 15's a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Polycap Capsule 15's is a combination of five drugs, namely: Simvastatin, Ramipril, Atenolol, Aspirin, and Hydrochlorothiazide. Polycap Capsule 15's is used for the prevention of cardiovascular events and stroke. Polycap Capsule 15's helps in lowering of blood pressure, heart rate, lipid levels, and decreases the stickiness of platelets. Simvastatin is a lipid-lowering agent that helps in lowering the levels of LDL (bad) cholesterol, triglycerides and raises the levels of HDL (good) cholesterol. Ramipril, Atenolol and Hydrochlorothiazide help in controlling blood pressure. Ramipril is an ACE inhibitor which relaxes the blood vessels and allows smooth blood flow. Atenolol is a beta-blocker that slows down the heart rate and makes it more efficient at pumping blood. Hydrochlorothiazide is a diuretic that helps remove unneeded water and salts from the body. Aspirin is an anti-platelet agent that decreases the formation of harmful clots by preventing the platelets from sticking together. Together, Polycap Capsule 15's helps in lowering the risk of a heart attack. Polycap Capsule 15's lowers the risk of heart attack or stroke by controlling blood pressure, lowering fat and increasing HDL levels.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Polycap Capsule 15's

  • Weakness
  • Indigestion
  • Constipation
  • Dizziness
  • Musculoskeletal pain

Drug Warnings

Do not take Polycap Capsule 15's if you are allergic to any of its contents, if you are taking fusidic acid or sacubitril. Inform your doctor if you are due to have surgery, drink large amounts of alcohol, if you have asthma, diabetes, overactive thyroid, pheochromocytoma (tumour of the adrenal gland), gout, glaucoma, stomach or intestinal bleeding or bleeding disorders, stomach ulcers, liver or kidney problems. Do not take Polycap Capsule 15's if you are pregnant, think you may be pregnant or if you are trying for pregnancy. Talk to a doctor immediately if you become pregnant while taking Polycap Capsule 15's. Consult your doctor before taking Polycap Capsule 15's if you are breastfeeding. Polycap Capsule 15's may cause dizziness, so be cautious while driving. Avoid consuming alcohol with Polycap Capsule 15's as it could lead to increased dizziness. Polycap Capsule 15's is not recommended for children as safety and effectiveness have not been established.

Drug-Drug Interactions

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RamiprilAliskiren
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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RamiprilAliskiren
Critical
How does the drug interact with Polycap Capsule:
Taking aliskiren together with Polycap Capsule may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Polycap Capsule with Aliskiren is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Polycap Capsule:
Taking Dofetilide and Polycap Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Polycap Capsule together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Polycap Capsule:
Taking Cisapride and Polycap Capsule can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Polycap Capsule together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
SimvastatinDarunavir
Critical
How does the drug interact with Polycap Capsule:
Combining Darunavir and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Darunavir and Polycap Capsule together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinFosamprenavir
Critical
How does the drug interact with Polycap Capsule:
Combining Fosamprenavir and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Fosamprenavir and Polycap Capsule together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinMifepristone
Critical
How does the drug interact with Polycap Capsule:
Combining Mifepristone with Polycap Capsule can increase the blood levels of Polycap Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Polycap Capsule with Mifepristone is not recommended, but can be taken if prescribed by the doctor. If you experience any symptoms, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
SimvastatinAtazanavir
Critical
How does the drug interact with Polycap Capsule:
Combining Atazanavir and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Atazanavir and Polycap Capsule together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-coloured urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinTelaprevir
Critical
How does the drug interact with Polycap Capsule:
Combining Telaprevir and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Telaprevir and Polycap Capsule together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SimvastatinErythromycin
Critical
How does the drug interact with Polycap Capsule:
Coadministration of erythromycin and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Erythromycin and Polycap Capsule together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain or weakness, dark-colored urine, joint pain, itching, fatigue, or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
SimvastatinIdelalisib
Critical
How does the drug interact with Polycap Capsule:
Combining Idelalisib and Polycap Capsule can increase the blood levels and effects of Polycap Capsule. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Idelalisib and Polycap Capsule together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low-salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans-fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FUSIDIC ACID
  • ERYTHROMYCIN
  • ESOMEPRAZOLE
  • LEVOTHYROXINE
  • PREGABALIN
  • FUROSEMIDE
  • SITAGLIPTIN
  • INSULIN GLARGINE
  • AMLODIPINE
  • METOPROLOL
  • ALPRAZOLAM
  • DULOXETINE
  • CLOPIDOGREL
  • CALCIUM
  • CHOLECALCIFEROL
  • VITAMIN D

Special Advise

  • Regular blood tests are advised to determine the effect of Polycap Capsule 15's on lipids. 
  • Consult your doctor immediately if you experience muscle pain, weakness, or tenderness, especially if associated with fever or tiredness.
  • Polycap Capsule 15's might affect test results for liver function and muscle enzyme (creatin-kinase). Inform the person doing the tests that you are taking Polycap Capsule 15's.
  • It is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke. 
  • Regularly monitor blood pressure levels, heart rate and electrolyte levels.

Disease/Condition Glossary

Heart attack: Heart attack or stroke occurs due to the blockage of blood flow to the heart muscle. The blockade usually occurs due to the build-up of fat/cholesterol in the coronary artery. High cholesterol levels might lead to a build-up of fat on the walls of the arteries leading to blockage of blood flow to the heart and other body parts, which could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely bad cholesterol and good cholesterol. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) which deposit fat in the arteries leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Symptoms of angina include pain or tightness in the chest, discomfort, pain in the neck, arms or back, weakness, lightheadedness and abnormal heartbeat. Risk factors include obesity, stress, smoking, high-fat diet, lack of exercise and genetics.

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