Posanat 100 mg Tablet 10's

₹6666

(Inclusive of all Taxes)

₹999.9 Cashback (15%)

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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About Posanat 100 mg Tablet

Posanat 100 mg Tablet is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Posanat 100 mg Tablet contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Take Posanat 100 mg Tablet as prescribed by your doctor. You are advised to take Posanat 100 mg Tablet for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of Posanat 100 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posanat 100 mg Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posanat 100 mg Tablet only if the benefits outweigh the risk. Before taking the Posanat 100 mg Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posanat 100 mg Tablet

Fungal infectionsProphylaxis of invasive Aspergillus and Candida infections in severely immunocompromised patients.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Posaconazole is an antifungal medication present in Posanat 100 mg Tablet . It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.

Storage

Keep Posanat 100 mg Tablet out of the sight and reach of children.

Drug Warnings

Inform your doctor if you are allergic or hypersensitive to any component present in Posanat 100 mg Tablet or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posanat 100 mg Tablet only if the benefits outweigh the risk. Before taking the Posanat 100 mg Tablet , inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. And also, let your doctor know before prescribing Posanat 100 mg Tablet if you have Arrhythmias and QTc Prolongation, liver problems, or low potassium, magnesium, or calcium levels in your blood.

Drug-Drug Interactions

PosaconazoleCerivastatin

Critical

PosaconazoleSaquinavir

Critical

Drug-Drug Interactions

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PosaconazoleCerivastatin

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking cerivastatin with Posanat 100 mg Tablet can increase the blood levels of cerivastatin.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and cerivastatin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, dark-colored urine, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

PosaconazoleSaquinavir

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking saquinavir together with Posanat 100 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and saquinavir, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

PosaconazoleTolvaptan

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking Tolvaptan and Posanat 100 mg Tablet together results in an increase in the levels and effects of Tolvaptan.

How to manage the interaction:
Although there is an interaction between Tolvaptan and Posanat 100 mg Tablet, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.

PosaconazoleSimvastatin

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking Posanat 100 mg Tablet with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posanat 100 mg Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

PosaconazolePimozide

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking pimozide with Posanat 100 mg Tablet can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

PosaconazoleEliglustat

Critical

How does the drug interact with Posanat 100 mg Tablet:
Taking eliglustat with Posanat 100 mg Tablet can increase the levels of eliglustat in the blood.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.

PosaconazoleIvabradine

Critical

How does the drug interact with Posanat 100 mg Tablet:
Using ivabradine together with Posanat 100 mg Tablet may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Posanat 100 mg Tablet together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

PosaconazoleTicagrelor

Critical

How does the drug interact with Posanat 100 mg Tablet:
Co-administration of Posanat 100 mg Tablet with Ticagrelor can increase the risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Posanat 100 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.

PosaconazoleSirolimus

Critical

How does the drug interact with Posanat 100 mg Tablet:
Coadministration of sirolimus with Posanat 100 mg Tablet can lower the levels of sirolimus in the blood.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet with sirolimus, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

PosaconazoleSilodosin

Critical

How does the drug interact with Posanat 100 mg Tablet:
Coadministration of silodosin and Posanat 100 mg Tablet may significantly increase the blood levels and effects of silodosin.

How to manage the interaction:
Although there is an interaction between Posanat 100 mg Tablet and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Take the medication as directed by the doctor and at regular intervals if you take Posanat 100 mg Tablet for more than one day.
Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posanat 100 mg Tablet .
Continue taking your normal regular diet unless your doctor prescribes a specific diet.
It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during Posanat 100 mg Tablet treatment to enhance a healthy lifestyle practice.

Side Effects of Posanat 100 mg Tablet

Diarrhoea
Nausea
Fever
Vomiting
Headache
Coughing
Low potassium levels in the blood

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

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Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Posanat 100 mg Tablet work?

Posanat 100 mg Tablet contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.

Is it ideal to use Posanat 100 mg Tablet with anticoagulants?

Posanat 100 mg Tablet is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanat 100 mg Tablet .

What medication should not be taken at the same time as Posanat 100 mg Tablet taking?

If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.

What are the Possible side effects with Posanat 100 mg Tablet ?

Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Posanat 100 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

How long do I need to use Posanat 100 mg Tablet ?

Take Posanat 100 mg Tablet as prescribed by your doctor. You are advised to take Posanat 100 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition.

Drug-Drug Interactions Checker List

TERFENADINE
ASTEMIZOLE
CISAPRIDE
PIMOZIDE
HALOFANTRINE
QUINIDINE

Special Advise

Regular blood tests are recommended before and while taking Posanat 100 mg Tablet to monitor liver functioning, especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by Candida.

Invasive aspergillosis: Invasive aspergillosis occurs when Aspergillus causes serious infection and usually affects people with weakened immune systems, such as those who have had an organ transplant or a stem cell transplant. Invasive aspergillosis most commonly affects the lungs but can also spread to other body parts.