Posanat 300 mg Injection 16.7 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹7600

(Inclusive of all Taxes)

₹1140.0 Cashback (15%)

Provide Delivery Location

Non returnable*

Know More

COD available

Online payment accepted

Prescription drug

Whats That

About Posanat 300 mg Injection 16.7 ml

Posanat 300 mg Injection 16.7 ml is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. Besides this, it is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Any disease caused by a fungus is known as a fungal infection.

Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Posanat 300 mg Injection 16.7 ml will be administered by a qualified healthcare professional. You may sometimes experience injection site reactions, fever, headache, chills or shaking, stomach pain, constipation, diarrhoea, nosebleeds and coughing. Most of these side effects of Posanat 300 mg Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posanat 300 mg Injection 16.7 ml or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posanat 300 mg Injection 16.7 ml only if the benefits outweigh the risk. Before taking the Posanat 300 mg Injection 16.7 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posanat 300 mg Injection 16.7 ml

Fungal infections

Directions for Use

Posanat 300 mg Injection 16.7 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. It is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Storage

Keep Posanat 300 mg Injection 16.7 ml out of the sight and reach of children.

Side effects of Posanat 300 mg Injection 16.7 ml

Liver Damage

Avoid alcohol as it may be harmful and worsen certain condition.
Take nutritional supplements only as advised by your doctor.
Limit sodium intake.
Consult your doctor for medications to treat your condition effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

High Body Temperature

Here's a comprehensive approach to managing medication-triggered fever:

Inform your doctor immediately if you experience a fever after starting a new medication.
Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
Monitor your body temperature to monitor fever progression.
Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Rash

Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
Protect your skin from extreme heat and try to apply wet compresses.
Soak in the cool bath, which gives a soothing impact to the affected area.

Shortness Of Breath

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Keep your doctor informed about your health condition and medicines to rule out any side effects. Posanat 300 mg Injection 16.7 ml is restricted to people sensitive to product constituents or other antifungal medicines. During pregnancy and lactation, posaconazole should only be used after careful risk/benefit considerations, so before taking Posanat 300 mg Injection 16.7 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is unknown whether it is safe to consume alcohol with Posanat 300 mg Injection 16.7 ml. However, as a precautionary measure, it is advisable not to take or limit alcohol.

Drug-Drug Interactions

PosaconazoleAtorvastatin

Critical

PosaconazoleZiprasidone

Critical

Drug-Drug Interactions

Login/Sign Up

PosaconazoleAtorvastatin

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking atorvastatin with Posanat 300 mg Injection 16.7 ml can increase the blood levels of atorvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml with atorvastatin, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

PosaconazoleZiprasidone

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Coadministration of Posanat 300 mg Injection 16.7 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

PosaconazoleLovastatin

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking lovastatin with Posanat 300 mg Injection 16.7 ml can increase the levels of lovastatin in the blood which can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Lovastatin and Posanat 300 mg Injection 16.7 ml, they can be taken together if advised by a doctor. However, contact a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.

PosaconazoleCisapride

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Posanat 300 mg Injection 16.7 ml is taken with Cisapride, it can lower the rate at which Cisapride is broken down in the body.

How to manage the interaction:
Taking Posanat 300 mg Injection 16.7 ml with Cisapride is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.

PosaconazoleIvabradine

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Using ivabradine together with Posanat 300 mg Injection 16.7 ml may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Posanat 300 mg Injection 16.7 ml together is generally not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

PosaconazoleRanolazine

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Posanat 300 mg Injection 16.7 ml is taken with Ranolazine, may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and ranolazine, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

PosaconazoleIsavuconazole

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Isavuconazole is taken with Posanat 300 mg Injection 16.7 ml, it can increase the levels of isavuconazole in the blood.

How to manage the interaction:
Although there is an interaction between isavuconazole and Posanat 300 mg Injection 16.7 ml, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

PosaconazolePimozide

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Taking pimozide with Posanat 300 mg Injection 16.7 ml can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.

PosaconazoleSilodosin

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
Coadministration of silodosin and Posanat 300 mg Injection 16.7 ml may significantly increase the blood levels and effects of silodosin.

How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.

PosaconazoleConivaptan

Critical

How does the drug interact with Posanat 300 mg Injection 16.7 ml:
When Posanat 300 mg Injection 16.7 ml is taken with Conivaptan, it can increase the blood levels and effects of conivaptan.

How to manage the interaction:
Although there is an interaction between Posanat 300 mg Injection 16.7 ml and conivaptan, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, or mood changes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

Take the medication as directed by the doctor and at regular intervals if you take Posanat 300 mg Injection 16.7 ml for more than one day.
Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posanat 300 mg Injection 16.7 ml.
Continue taking your normal regular diet unless your doctor prescribes a specific diet.
It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcoholic beverages and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during the Posanat 300 mg Injection 16.7 ml treatment to enhance a healthy lifestyle practice.

Side Effects of Posanat 300 mg Injection 16.7 ml

Injection site reactions
Fever
Headache
Chills or shaking
Constipation
Stomach pain
Diarrhoea
Nosebleeds
Coughing

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Posanat 300 mg Injection 16.7 ml Substitute

Critposa Injection 16.7 ml

by AYUR

₹409.64per tablet

Posatral 300mg Injection 16.7 ml

by Others

₹406.72per tablet

Posalup 300Mg/16.7Ml Injection 1's

by Others

₹7232.40per tablet

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

How does Posanat 300 mg Injection 16.7 ml work?

Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.

Is it ideal to use Posanat 300 mg Injection 16.7 ml with anticoagulants?

Posanat 300 mg Injection 16.7 ml is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanat 300 mg Injection 16.7 ml.

In which conditions should I avoid using the Posanat 300 mg Injection 16.7 ml?

If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.

What are the Possible side effects with Posanat 300 mg Injection 16.7 ml?

Posanat 300 mg Injection 16.7 ml may cause side effects like injection site reactions, diarrhoea, nausea, fever, vomiting, headache and coughing, although not everybody gets them. Most of these side effects of Posanat 300 mg Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Is Posanat 300 mg Injection 16.7 ml causes nosebleeds?

In some cases, using Posanat 300 mg Injection 16.7 ml may lead to nosebleeds as a side effect. It does not require medical attention and gradually resolves over time. However, if the side effects persist or worsen, please consult your doctor.

Drug-Drug Interactions Checker List

APIXABAN

Disease/Condition Glossary

Fungal infection: Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by the species Candida.

Invasive aspergillosis: Invasive aspergillosis occurs when Aspergillus causes serious infection and usually affects people with weakened immune systems, such as those who have had an organ transplant or a stem cell transplant. Invasive aspergillosis most commonly affects the lungs but can also spread to other body parts.