Posaone 300 Injection 16.7 ml is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. Besides this, it is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Any disease caused by a fungus is known as a fungal infection.

Posaone 300 Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Posaone 300 Injection 16.7 ml will be administered by a qualified healthcare professional. You may sometimes experience injection site reactions, fever, headache, chills or shaking, stomach pain, constipation, diarrhoea, nosebleeds and coughing. Most of these side effects of Posaone 300 Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posaone 300 Injection 16.7 ml or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posaone 300 Injection 16.7 ml only if the benefits outweigh the risk. Before taking the Posaone 300 Injection 16.7 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. It is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posaone 300 Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

• Injection site reactions
• Fever
• Headache
• Chills or shaking
• Constipation
• Stomach pain
• Diarrhoea
• Nosebleeds
• Coughing

Keep your doctor informed about your health condition and medicines to rule out any side effects. Posaone 300 Injection 16.7 ml is restricted to people sensitive to product constituents or other antifungal medicines. During pregnancy and lactation, posaconazole should only be used after careful risk/benefit considerations, so before taking Posaone 300 Injection 16.7 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is unknown whether it is safe to consume alcohol with Posaone 300 Injection 16.7 ml. However, as a precautionary measure, it is advisable not to take or limit alcohol.

Drug-Drug Interactions: Posaone 300 Injection 16.7 ml may interact with anticoagulant medication (e.g. apixaban).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

• APIXABAN

• Take the medication as directed by the doctor and at regular intervals if you take Posaone 300 Injection 16.7 ml for more than one day.
• Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posaone 300 Injection 16.7 ml.
• Continue taking your normal regular diet unless your doctor prescribes a specific diet.
• It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcoholic beverages and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
• A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during the Posaone 300 Injection 16.7 ml treatment to enhance a healthy lifestyle practice.

Fungal infection: Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by the species Candida.

Invasive aspergillosis: Invasive aspergillosis occurs when Aspergillus causes serious infection and usually affects people with weakened immune systems, such as those who have had an organ transplant or a stem cell transplant. Invasive aspergillosis most commonly affects the lungs but can also spread to other body parts.