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About Posatral 300 Tablet 10's
Posatral 300 Tablet 10's is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections when other antifungal medicines have not worked, or you have had to stop taking them. It is also indicated for preventing invasive Aspergillus and Candida infections in patients at high risk of developing these infections due to being severely immunocompromised, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.
Posatral 300 Tablet 10's contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.
Take Posatral 300 Tablet 10's as prescribed by your doctor. You are advised to take Posatral 300 Tablet 10's for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood. Most of these side effects of Posatral 300 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Inform your doctor if you are allergic or hypersensitive to any component present in Posatral 300 Tablet 10's or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posatral 300 Tablet 10's only if the benefits outweigh the risk. Before taking the Posatral 300 Tablet 10's, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.
Uses of Posatral 300 Tablet 10's
Directions for Use
Medicinal Benefits
Posaconazole is an antifungal medication present in Posatral 300 Tablet 10's. It is effective in treating fungal infections in adults. It is also indicated for preventing invasive Aspergillus and Candida infections in patients who are severely immunocompromised and at high risk of developing these infections, such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD) or those with hematologic malignancies with prolonged neutropenia from chemotherapy.
Storage
Drug Warnings
Inform your doctor if you are allergic or hypersensitive to any component present in Posatral 300 Tablet 10's or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posatral 300 Tablet 10's only if the benefits outweigh the risk. Before taking the Posatral 300 Tablet 10's, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions. And also, let your doctor know before prescribing Posatral 300 Tablet 10's if you have Arrhythmias and QTc Prolongation, liver problems, or low potassium, magnesium, or calcium levels in your blood.
Diet & Lifestyle Advise
Side Effects of Posatral 300 Tablet 10's
Habit Forming
Therapeutic Class
Product Substitutes
We provide you with authentic, trustworthy and relevant information
Posatral 300 Tablet 10's contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Posatral 300 Tablet 10's is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posatral 300 Tablet 10's.
If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.
Like all medicines, this medicine may cause side effects such as diarrhoea, nausea, fever, vomiting, headache, coughing and low potassium levels in the blood, although not everybody gets them. Most of these side effects of Posatral 300 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Take Posatral 300 Tablet 10's as prescribed by your doctor. You are advised to take Posatral 300 Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
Fungal infection: Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by Candida.
Invasive aspergillosis: Invasive aspergillosis occurs when Aspergillus causes serious infection and usually affects people with weakened immune systems, such as those who have had an organ transplant or a stem cell transplant. Invasive aspergillosis most commonly affects the lungs but can also spread to other body parts.
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Alcohol
Caution
It is unknown whether Posatral 300 Tablet 10's alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
Pregnancy
Caution
Posatral 300 Tablet 10's should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posatral 300 Tablet 10's.
Breast Feeding
Caution
There is no substantial research yet on using Posatral 300 Tablet 10's in breastfeeding/nursing mothers. Inform your doctor if you are a nursing mother before taking Posatral 300 Tablet 10's; your doctor will decide whether Posatral 300 Tablet 10's can be taken by breastfeeding mothers.
Driving
Caution
It is unknown whether Posatral 300 Tablet 10's alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.
Liver
Caution
Inform your doctor before receiving the Posatral 300 Tablet 10's if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
Caution
Inform your doctor before receiving the Posatral 300 Tablet 10's if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
Safe if prescribed
Your doctor will weigh the benefits and potential risks before prescribing Posatral 300 Tablet 10's.