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Reviewed By Sunny S , MBBS

About Poziglim 2 Tablet 10's

Poziglim 2 Tablet 10's belongs to a group of medicines known as 'antidiabetics', used to treat type 2 (non-insulin-dependent) diabetes mellitus. In type 2 diabetes the body doesn't make enough insulin, or the insulin is not effectively used by the body. This is a type of diabetes that usually develops in adulthood. Insulin is a natural substance released by the body to break down the sugar of the body.

Poziglim 2 Tablet 10's is a combination of two drugs namely 'Pioglitazone' and 'Glimepiride'. Pioglitazone belongs to the class of thiazolidinedione (TZD) also called 'glitazones' which helps control the level of sugar in your blood by helping your body to make better use of the insulin it produces. Glimepiride belongs to a class of medicines known as 'sulfonylureas', which works by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This drug also works best for individuals whose bodies naturally produce insulin. 

Take Poziglim 2 Tablet 10's as suggested by the doctor. You are advised to take Poziglim 2 Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as upper respiratory tract infection, headache, sinusitis, myalgia (muscle pain) and pharyngitis. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these undesirable effects persistently.

Poziglim 2 Tablet 10's should not be taken if you have type 1 diabetes mellitus, if you are hypersensitive (allergic) to Poziglim 2 Tablet 10's or any of the other ingredients of Poziglim 2 Tablet 10's, have heart failure or have had heart failure in the past, diabetic ketoacidosis (a complication of diabetes causing rapid weight loss, nausea or vomiting), severe kidney or liver disease, bladder cancer. Please inform your doctor if you have any heart disease or planning to get pregnant or breastfeeding. Safety and efficacy of Poziglim 2 Tablet 10's in children under 18 years have not been established, so it should not be given to them. Poziglim 2 Tablet 10's is safe to taken by elderly persons whose age is 65 or over if prescribed by the doctor.

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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Poziglim 2 Tablet 10's

Type 2 diabetes mellitus

Medicinal Benefits

Poziglim 2 Tablet 10's is an antidiabetic drug used along with a proper diet and exercise to control high blood sugar (hyperglycemia) in patients with type 2 diabetes. Poziglim 2 Tablet 10's works by helping to restore your body's appropriate response to insulin, thereby lowering your blood sugar. Poziglim 2 Tablet 10's may be used on its own in patients who are unable to take metformin and where treatment with diet and exercise has failed to control blood sugar. As Poziglim 2 Tablet 10's helps to control the high blood sugar levels in the body, so it prevents the risk of blindness, nerve problems, kidney damage and other serious medical issues like a heart attack.

Side Effects of Poziglim 2 Tablet 10's

  • Headache
  • Sinusitis
  • Myalgia (muscle pain)
  • Upper respiratory tract infection
  • Urinary tract infection
  • Diarrhea
  • Nausea
  • Pharyngitis (inflammation of pharynx located back of neck)

Directions for Use

Take Poziglim 2 Tablet 10's as advised by the doctor. Swallow it as a whole with a full glass of water. Do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Poziglim 2 Tablet 10's should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Poziglim 2 Tablet 10's suddenly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney damage (nephropathy), and nerve damage (neuropathy). Poziglim 2 Tablet 10's is used to lower the blood sugar however if your sugar level gets reduced to a very low level and you start experiencing symptoms including hunger, sweating, dizziness, headache and feeling shaky. To treat such a condition, it is suggested to keep a fast-acting source of sugar in your bag that includes hard candy, raisins, and non-diet soda. Fluid retention (edema) may occur and can lead to congestive heart failure so, combination use with insulin and use in heart failure may increase the risk in patients taking Poziglim 2 Tablet 10's. You should not take Poziglim 2 Tablet 10's if you have kidney disease, as measured by a blood test. Poziglim 2 Tablet 10's, when used with or without insulin, tends to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Increased fractures may be reported in some women taking Poziglim 2 Tablet 10's. Patients with bladder cancer and macular edema (fluid build-up in the macula part of the retina of the eye) should consult the doctor before using Poziglim 2 Tablet 10's.

Therapeutic Class

ANTIDIABETICS

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
GlimepirideBisoprolol
Severe

Drug-Drug Interactions

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PioglitazoneGatifloxacin
Critical
How does the drug interact with Poziglim 2 Tablet 10's:
Co-administration of Poziglim 2 Tablet 10's with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, excessive sweating, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without a doctor's advice.
GlimepirideBisoprolol
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Concomitant use of bisoprolol with Poziglim 2 Tablet 10's may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar). It may also mask some of the symptoms of hypoglycemia such as palpitation, tremor, and rapid heartbeat, making it more difficult to recognize an oncoming episode.

How to manage the interaction:
Although there may be an interaction, bisoprolol can be taken with Poziglim 2 Tablet 10's if prescribed by the doctor. Consult the prescriber if you develop symptoms of low blood sugar like shakiness, dizziness, sweating, nausea, hunger, weakness, or lightheadedness.
GlimepirideKetoprofen
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Taking Ketoprofen with Poziglim 2 Tablet 10's may increase the risk of hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with Ketoprofen if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
GlimepirideAmprenavir
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Co-administration of Amprenavir and Poziglim 2 Tablet 10's may interfere with blood glucose control and reduce the effectiveness of Poziglim 2 Tablet 10's.

How to manage the interaction:
Although taking Poziglim 2 Tablet 10's and Amprenavir together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideCiprofloxacin
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Taking ciprofloxacin with Poziglim 2 Tablet 10's can cause both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking ciprofloxacin and Poziglim 2 Tablet 10's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat or increased thirst, increased hunger, and increased urination. Do not discontinue the medications without consulting a doctor.
GlimepirideBumetanide
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Bumetanide may interfere with blood glucose control and reduce the effectiveness of Poziglim 2 Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with bumetanide if prescribed by the doctor. Monitoring of blood glucose levels is advised.
GlimepirideParoxetine
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Taking Poziglim 2 Tablet 10's with Paroxetine may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideVoriconazole
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Co-administration of Poziglim 2 Tablet 10's with Voriconazole may increase the blood levels and effects of Poziglim 2 Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with voriconazole if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideCitalopram
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Taking Poziglim 2 Tablet 10's with Citalopram may increase the risk of low blood sugar.

How to manage the interaction:
Although there is a possible interaction, Poziglim 2 Tablet 10's can be taken with Citalopram if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideGrepafloxacin
Severe
How does the drug interact with Poziglim 2 Tablet 10's:
Co-administration of Poziglim 2 Tablet 10's with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.

How to manage the interaction:
Although there is a possible interaction between Poziglim 2 Tablet 10's and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • GEMFIBROZIL
  • RIFAMPICIN
  • COLESEVELAM
  • METOPROLOL
  • PROPRANOLOL
  • TIMOLOL

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins and a quarter with whole grains.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with whole grain foods and increase intake of fruits and veggies and other fiber-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yogurt, fat-free milk, and cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

Special Advise

  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice. 
  • Take short frequent meals, avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits, or 3 teaspoons of honey/sugar, and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • It is always better that your physician knows about any underlying conditions like kidney disease or liver disease, prior heart attack, alcohol intake, etc before the doctor prescribes you this medicine.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
  • Try to quit smoking and reduce intake of carbohydrate-rich food like potatoes, rice, mangoes, bread, sugar, etc.

Disease/Condition Glossary

Type 2 diabetes: It is a condition where the body is unable to make sufficient insulin, or the insulin that it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycemia). Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also include neuropathy (nerve problems), nephropathy (kidney problems) and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction and increase chance of heart attack or stroke.

Poziglim 2 Tablet 10's Substitute

Substitutes safety advice
  • Pioglar-G Tablet 10's

    14.76per tablet
  • Pozitive-G2 Tablet 10's

    10.08per tablet
  • Piogood G2 Tablet 10's

    8.10per tablet
  • Pionorm-G Tablet 10's

    6.75per tablet
  • ZOREP 2MG TABLET

    7.15per tablet
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