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Reviewed By Sunny S , MBBS
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Non returnable*
COD available

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Manufacturer/Marketer :

Talent India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Preega M-75 SR Tablet

Preega M-75 SR Tablet belongs to a group of medications known as 'anticonvulsants' used to manage neuropathic pain due to damaged nerves. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. 

Preega M-75 SR Tablet is a combination of two drugs: Methylcobalamin/Mecobalamin (vitamin B12) and Pregabalin (anti-convulsant). Mecobalamin protects nerve fibres and rejuvenates nerve cells by producing a substance called myelin. Pregabalin works by changing how nerves send messages to the brain. Together, Preega M-75 SR Tablet helps to treat neuropathic pain (pain due to nerve damage). 

Take Preega M-75 SR Tablet as prescribed by your doctor. Depending on your medical condition, you are advised to take Preega M-75 SR Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience common side effects such as nausea, vomiting, stomach pain, diarrhoea, loss of appetite, heartburn, dry mouth, dizziness, sleepiness, and uncoordinated body movements. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Preega M-75 SR Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Preega M-75 SR Tablet causes drowsiness and dizziness, so drive only if you are alert. Preega M-75 SR Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Preega M-75 SR Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Let your doctor know if you have a history of heart disease, severe kidney disease, disorders of the stomach or gut/bowel, and diabetes before using the Preega M-75 SR Tablet . 

Uses of Preega M-75 SR Tablet

Neuropathic pain

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Preega M-75 SR Tablet is a combination of two drugs: Mecobalamin and Pregabalin. Mecobalamin is used to restore vitamin B12 in the body to treat damaged nerve conditions due to diabetes or other traumatic situations. It also has a neuroprotective activity that helps the nerve cells to function properly and treat neuropathic pain. On the other side, Pregabalin prevents neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in your body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body. Overall it reduces the pain which has been damaged or irritated due to conditions like chronic conditions, diabetes, trauma or epilepsy. Together, Preega M-75 SR Tablet helps to treat neuropathic pain.

Storage

Keep Preega M-75 SR Tablet out of the sight and reach of children.
Side effects of Preega M-75 SR Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

Please do not stop taking Preega M-75 SR Tablet without consulting your doctor as it could cause withdrawal symptoms. Women of child-bearing potential should use effective contraception.  Inform your doctor before taking Preega M-75 SR Tablet if you have heart problems, bipolar syndrome, severe liver disease or porphyria, diabetes, and asthma. Please do not stop taking Preega M-75 SR Tablet without consulting your doctor as it could cause withdrawal symptoms. Avoid consuming alcohol along with Preega M-75 SR Tablet as it could lead to increased drowsiness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies such as killing or harming yourself. Preega M-75 SR Tablet contains Pregabalin, which can decrease sperm count and may affect fertility in men. Do not exceed the prescribed dose or duration of treatment. 

Drug-Drug Interactions

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PregabalinSodium oxybate
Severe

Drug-Drug Interactions

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PregabalinSodium oxybate
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Sodium oxybate together with Preega M-75 SR Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Preega M-75 SR Tablet with Sodium oxybate together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult the doctor. For at least six hours after taking sodium oxybate, avoid operating machinery or engaging in potentially dangerous activities. Also, be careful when getting up from a sitting or lying down posture. Do not stop using any medications without talking to a doctor.
How does the drug interact with Preega M-75 SR Tablet:
Taking Ketamine with Preega M-75 SR Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Preega M-75 SR Tablet and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinHydrocodone
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Hydrocodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydrocodone and Preega M-75 SR Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinCodeine
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Codeine may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Codeine and Preega M-75 SR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinEsketamine
Severe
How does the drug interact with Preega M-75 SR Tablet:
When Preega M-75 SR Tablet and Esketamine are taken together, it may increase the risk of side effects.

How to manage the interaction:
Although taking Preega M-75 SR Tablet and Esketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
How does the drug interact with Preega M-75 SR Tablet:
Using Tapentadol together with Preega M-75 SR Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Preega M-75 SR Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Preega M-75 SR Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Preega M-75 SR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Preega M-75 SR Tablet and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinDezocine
Severe
How does the drug interact with Preega M-75 SR Tablet:
Using Preega M-75 SR Tablet together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Preega M-75 SR Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Side Effects of Preega M-75 SR Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhea
  • Heartburn
  • Dryness in mouth
  • Dizziness
  • Blurred vision

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Preega M-75 SR Tablet is a combination of two drugs: Pregabalin (antiepileptic) and Mecobalamin (vitamin B12). Pregabalin improves nerve signal conduction of damaged nerves. Methylcobalamin is a form of Vitamin B12 that helps in the regeneration of damaged nerves and helps produce the myelin sheath (outer protecting layer of nerves). Thus, Preega M-75 SR Tablet promotes healing of damaged nerve and improves nerve conduction in diabetes or traumatic conditions.

Dry mouth could be a side-effect of Preega M-75 SR Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Preega M-75 SR Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.

Do not discontinue Preega M-75 SR Tablet without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Preega M-75 SR Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Preega M-75 SR Tablet ; your doctor will reduce the dose gradually.

Preega M-75 SR Tablet is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Drug-Drug Interactions Checker List

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  • LISINOPRIL
  • MOEXIPRIL
  • PERINDOPRIL
  • QUINAPRIL
  • RAMIPRIL

Special Advise

  • Preega M-75 SR Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
  • Preega M-75 SR Tablet can cause dry mouth, so in that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Preega M-75 SR Tablet as it may increase drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Preega M-75 SR Tablet ; your doctor will decide whether Preega M-75 SR Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Preega M-75 SR Tablet causes drowsiness, sleepiness, and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Preega M-75 SR Tablet should not be given to children as the safety and efficacy have not been established.

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