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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Pregabrit Plus Capsule 10's

Pregabrit Plus Capsule 10's is a combination of medicine indicated in the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. Symptoms of neuropathic pain include shooting and burning pain followed by tingling and numbness (loss of sensation). Neuropathic pain can be caused due to amputation of limbs, diabetic neuropathy (nerve damage due to excess blood sugar level), excessive alcohol intake (alcoholism) and cancer treatment via chemotherapy.

Pregabrit Plus Capsule 10's is a combination of five drugs: Pregabalin, Methylcobalamin, Alpha-lipoic acid, Pyridoxine, and Folic acid. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in delivering essential nutrients to the nerves. Together, Pregabrit Plus Capsule 10's provides relief from neuropathic pain.

Take Pregabrit Plus Capsule 10's with or without food. Swallow Pregabrit Plus Capsule 10's as a whole with a glass of water; do not chew, or break it. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, nausea, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Pregabrit Plus Capsule 10's may cause drowsiness and dizziness, so drive only if you are alert. Pregabrit Plus Capsule 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabrit Plus Capsule 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

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Uses of Pregabrit Plus Capsule 10's

Neuropathic pain

Medicinal Benefits

Pregabrit Plus Capsule 10's is a combination of five drugs: Pregabalin (anti-convulsant or antiepileptic), methylcobalamin (vitamin B12), alpha-lipoic acid (antioxidant), pyridoxine (vitamin B6), and folic acid (vitamin B9). Pregabrit Plus Capsule 10's is used to treat neuropathic pain. Pregabalin affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. Methylcobalamin and Pyridoxine help in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Folic acid helps in providing essential nutrients to the nerves. Together, Pregabrit Plus Capsule 10's helps in providing relief from neuropathic pain.

Side Effects of Pregabrit Plus Capsule 10's

  • Dizziness
  • Sleepiness
  • Tiredness
  • Nausea
  • Vomiting

Directions for Use

Take Pregabrit Plus Capsule 10's with or without food. Swallow Pregabrit Plus Capsule 10's as a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Pregabrit Plus Capsule 10's if you are allergic to any of its contents. Inform your doctor if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Pregabrit Plus Capsule 10's may cause drowsiness and dizziness, so drive only if you are alert. Pregabrit Plus Capsule 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabrit Plus Capsule 10's as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Therapeutic Class

ANTICONVULSANT

Drug-Drug Interactions

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PregabalinBuprenorphine
Severe
PregabalinPethidine
Severe

Drug-Drug Interactions

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PregabalinBuprenorphine
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Buprenorphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Buprenorphine and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinPethidine
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinAlfentanil
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Alfentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Pregabrit Plus Capsule 10's and Alfentanil together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinDezocine
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinNalbuphine
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Nalbuphine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Nalbuphine and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTramadol
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
When Tramadol is used with Pregabrit Plus Capsule 10's, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinKetamine
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Taking Ketamine with Pregabrit Plus Capsule 10's may increase the risk of side effects.

How to manage the interaction:
Although taking Pregabrit Plus Capsule 10's and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinFentanyl
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Fentanyl can increase the risk of side effects.

How to manage the interaction:
Although taking fentanyl together with Pregabrit Plus Capsule 10's can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you have dizziness, sleepiness, difficulty concentrating, or impairment in judgment. Do not stop taking any medication without consulting a doctor.
PregabalinHydromorphone
Severe
How does the drug interact with Pregabrit Plus Capsule 10's:
Using Pregabrit Plus Capsule 10's together with Hydromorphone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Hydromorphone and Pregabrit Plus Capsule 10's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • MIRTAZAPINE
  • FLUOXETINE
  • SERTRALINE
  • CODEINE
  • FENTANYL
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • GABAPENTIN
  • PHENOBARBITAL
  • PHENYTOIN
  • DIAZEPAM
  • ALPRAZOLAM
  • METFORMIN
  • METHOTREXATE
  • SULFASALAZINE
  • CHLORAMPHENICOL
  • LEVODOPA

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

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Author Details

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Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of senses is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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