Pregaprime Tablet 10's is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or malfunctioning of the nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

Pregaprime Tablet 10's is a combination of three drugs: Pregabalin, methylcobalamin and alpha-lipoic acid. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Together, Pregaprime Tablet 10's helps in providing relief from neuropathic pain.

You are advised to take Pregaprime Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Pregaprime Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Pregaprime Tablet 10's should not be given to children as the safety and effectiveness have not been established. Avoid consuming alcohol along with Pregaprime Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Pregaprime Tablet 10's is used to treat neuropathic pain. Pregaprime Tablet 10's is a combination of three drugs: Pregabalin, methylcobalamin and alpha-lipoic acid. Pregabalin is an anticonvulsant which affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Methylcobalamin is a form of vitamin B12 which helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant which helps in providing a protective effect on the nerve tissues and brain. Together, Pregaprime Tablet 10's helps in providing relief from neuropathic pain.

• Dizziness
• Tiredness
• Nausea
• Dry mouth
• Constipation
• Vomiting

Do not take Pregaprime Tablet 10's if you are allergic to any of its contents. Inform your doctor before taking Pregaprime Tablet 10's if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Pregaprime Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Pregaprime Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregaprime Tablet 10's as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions: Pregaprime Tablet 10's may interact with antidepressant medications (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline), anticonvulsants (gabapentin), anti-anxiety medications (diazepam, alprazolam), anti-diabetic medications (metformin), antibiotic medications (chloramphenicol), and pain killers (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol).

Drug-Food Interactions: Avoid consumption of alcohol while taking Pregaprime Tablet 10's as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Inform your doctor if you have suicidal tendencies, angioedema, creatine kinase elevations, peripheral oedema, malabsorption or anaemia.

• AMITRIPTYLINE
• DULOXETINE
• MIRTAZAPINE
• FLUOXETINE
• SERTRALINE
• CODEINE
• FENTANYL
• HYDROCODONE
• MORPHINE
• OXYCODONE
• TRAMADOL
• GABAPENTIN
• DIAZEPAM
• ALPRAZOLAM
• METFORMIN
• CHLORAMPHENICOL

• Include food rich in vitamin B and D in your diet.
• Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
• Exercising regularly helps in improving overall health and combating pain. 
• Rest well, and get plenty of sleep.
• Try taking a warm bath, as it can be soothing.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
• Acupuncture can be helpful by stimulating pressure points.
• Using essential oils for massages can help increase circulation.

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).