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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
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Whats That

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Composition :

PREGABALIN-50MG

Manufacturer/Marketer :

Arches Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pregatel 50 mg Tablet

Pregatel 50 mg Tablet belongs to a group of medications called 'anti-convulsants', primarily used in the prevention of neuropathic pain, epilepsy (seizure episodes), fibromyalgia (musculoskeletal pain), and neuralgia (pain due to damaged/irritated nerve). Neuropathic pain is chronic nerve pain usually caused by damaged nerves due to a variety of diseases like diabetes, shingles (viral infection that causes a painful rash), spinal cord injury, and injuries to tissue, muscles, or joints.

Pregatel 50 mg Tablet contains 'Pregabalin', which works by calming the damaged or overactive nerves in the body that may cause nerve or musculoskeletal pain or seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

In some cases, Pregatel 50 mg Tablet might cause side effects like dizziness, somnolence (sleepiness/drowsiness), dry mouth, oedema (fluid overload with swelling), blurred vision, weight gain and abnormal thinking (difficulty with concentration/attention). Most of these side effects do not require medical attention. However, if the side effects persist or worsen, consult a doctor.

Tell your doctor if you are facing symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle pain, soreness, weakness, kidney, liver, or heart diseases.  Caution is required before giving Pregatel 50 mg Tablet to pregnant or breastfeeding women. The safety and effectiveness in children less than 18 years of age have not been established, so Pregatel 50 mg Tablet should not be given to them.

Uses of Pregatel 50 mg Tablet

Neuropathic pain (nerve pain), Epilepsy (seizures/fits), Fibromyalgia (musculoskeletal pain)

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. Do not crush, chew, or break it.Oral solution/Syrup: Shake the bottle well before use. Take the prescribed dose with the help of a measuring cup/dosing syringe/dropper.

Medicinal Benefits

Pregatel 50 mg Tablet belongs to a group of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by calming the damaged or overactive nerves in the body that may cause pain or seizures, thereby decreasing the number of pain signals sent out by damaged nerves in the body.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pregatel 50 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Blood flow to the brain and the rest of the body is increased by physical activity. This could help you maintain your memory.
  • Reading, solving puzzles, and picking up new skills are examples of mental workouts that can keep the brain engaged and enhance memory retention.
  • Maintaining an active social life enhances memory and brain stimulation.
  • Relaxation methods like yoga, meditation, and deep breathing can help because long-term stress can affect memory.
  • Drink plenty of water and stay hydrated.
  • Limit the intake of alcohol and caffeine.
  • Maintain good hygiene habits.
  • Avoid holding on and empty the bladder at regular intervals.
  • Try to quit smoking.
  • Perform balance exercises like heel raises, standing on one leg, and weight shifts with the guidance of a physical therapist.
  • Focus on strengthening leg muscles and core muscles for better stability.
  • Stay hydrated by drinking plenty of water as dehydration may lead to unsteadiness and dizziness.
  • Wear low-heeled shoes with good tread for better grip.
  • Change your surroundings by removing tripping hazards like clutter, loose rugs and poorly lit areas.
  • Avoid sudden position changes; stand up slowly and take your time to move around.
  • Watch out for rapid head movements that might trigger dizziness.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.

Drug Warnings

Do not take Pregatel 50 mg Tablet if you are known to be allergic to any of its contents. Inform your doctor if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic lung diseases, muscle weakness, heart problems, liver/kidney impairment. Caution is required before giving Pregatel 50 mg Tablet to pregnant or breastfeeding women. The safety and effectiveness of Pregatel 50 mg Tablet in children under 18 years of age have not been established, so Pregatel 50 mg Tablet should not be given to them. Taking Pregatel 50 mg Tablet with opioids analgesics or painkillers like oxycodone can cause respiratory failure, coma, and even leading to death, so avoid its intake together. If you are taking any sleeping pills or tranquillizers, tell your doctor about this as Pregatel 50 mg Tablet interacts with these drugs and causes sleepiness, drowsiness and dizziness and affects your daily activity. Immediately contact a doctor if you have swelling of your face, mouth, tongue, lips, gums, neck, or throat (angioedema).

Drug-Drug Interactions

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PregabalinPethidine
Severe
PregabalinOxycodone
Severe

Drug-Drug Interactions

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PregabalinPethidine
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Pethidine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pethidine and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinOxycodone
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Oxycodone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking oxycodone and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinRemifentanil
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Remifentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking remifentanil and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTapentadol
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Tapentadol together with Pregatel 50 mg Tablet may cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Pregatel 50 mg Tablet with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not exceed the doses or frequency and duration of use advised by the doctor. Do not discontinue any medications without consulting a doctor.
PregabalinKetamine
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Taking Ketamine with Pregatel 50 mg Tablet may increase the risk of side effects.

How to manage the interaction:
Although taking Pregatel 50 mg Tablet and ketamine together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms such as dizziness, drowsiness, confusion, difficulty concentrating, breathing difficulty, consult the doctor. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinMethadone
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Methadone causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking methadone and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinTramadol
Severe
How does the drug interact with Pregatel 50 mg Tablet:
When Tramadol is used with Pregatel 50 mg Tablet, it may possibly lead to side effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Although taking tramadol and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinDezocine
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Dezocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking Dezocine and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinSufentanil
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Sufentanil causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking sufentanil and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.
PregabalinPentazocine
Severe
How does the drug interact with Pregatel 50 mg Tablet:
Using Pregatel 50 mg Tablet together with Pentazocine causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate and loss of consciousness).

How to manage the interaction:
Although taking pentazocine and Pregatel 50 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience impaired judgment, reaction time, and motor coordination, dizziness, sleepiness, and difficulty concentrating, consult the doctor immediately. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Avoid driving or operating dangerous machinery. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a diet rich in fruits, vegetables, whole grains, omega-3 rich foods. Avoid fried foods, high-fat dairy products, pastries, and processed foods, as they may worsen neuropathic pain.
  • Do regular exercise and maintain a healthy weight.
  • Avoid the consumption of alcohol as it may increase dizziness or drowsiness.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Pregatel 50 mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Pregatel 50 mg Tablet works by blocking the pain centre that interferes with pain messages that travel through the brain and spine (central nervous system). In epilepsy, it prevents episodes of fits by reducing the abnormal electrical activity in the brain and calming the overactive nerves.

Yes, Pregatel 50 mg Tablet may cause weight gain because it increases your hunger. However, regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Please consult the doctor if you have any further concerns about keeping your weight stable.

No, you are not recommended to take Pregatel 50 mg Tablet with tramadol as co-administration of these medicines may cause breathing problems, drowsiness, and even lead to a stage of coma. So, before using Pregatel 50 mg Tablet with painkillers like oxycodone or any other opioid analgesics, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Drug-Drug Interactions Checker List

  • MORPHINE
  • FENTANYL
  • OXYCODONE
  • TRAMADOL
  • CODEINE
  • LORAZEPAM
  • DIAZEPAM
  • CLONAZEPAM

Special Advise

Do not take Pregatel 50 mg Tablet for a prolonged time; it may lead to mental or physical dependence on Pregatel 50 mg Tablet .

Disease/Condition Glossary

Neuropathic pain (nerve pain): It is a chronic nerve pain condition usually caused by damaged or irritated nerves due to conditions like diabetes, shingles (viral infection with painful rash), spinal cord injury, or injuries to tissue/muscles/joints. Symptoms of nerve pain sensation are hot, burning, throbbing, shooting, stabbing, sharp, cramping, tingling, and numbness. 

Fibromyalgia (musculoskeletal pain): It is a chronic condition that may cause pain, muscle stiffness and tenderness, tiredness, difficulty falling asleep or staying asleep and mental distress, an impact on physical and social functioning and overall quality of life.

Epilepsy (fits): It is a nervous system disorder with a sudden rush of electricity in the brain due to disturbed nerve cell (neuron) activity in the brain. Seizures are of two types, namely: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures can make people confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

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