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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

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Composition :

ESOMEPRAZOLE-40MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Presto-ES Injection

Presto-ES Injection belongs to the class of drugs known as proton pump inhibitors used for the short-term treatment of gastroesophageal reflux disease (GERD) and stomach ulcers caused by NSAIDs. It also reduces the risk of further ulcer bleeding following an endoscopy in adults. Presto-ES Injection is indicated in adults and children aged 1 month or older who have had damage to their oesophagus and are unable to take esomeprazole by mouth.

Presto-ES Injection contains 'Esomeprazole' that works by reducing the amount of acid made in the stomach. As a result, it relieves symptoms of gastroesophageal reflux disease (GERD) and stomach ulcers.

Presto-ES Injection will be administered by a healthcare professional; do not self-administer. In some cases, Presto-ES Injection may cause headache, diarrhoea, stomach pain, constipation, wind (flatulence), nausea, vomiting, and injection site reactions such as pain, itching, swelling or redness. Most of these side effects do not require medical attention and may resolve with time. However, if they persist or worsen, consult a doctor.

Do not take Presto-ES Injection if you have/had any allergy or hypersensitivity to esomeprazole, any other proton pump inhibitor medications (such as pantoprazole, lansoprazole, rabeprazole, or omeprazole), or any of the other ingredients in Presto-ES Injection. Let your doctor know if you are taking nelfinavir (used to treat HIV infection). Consult your doctor if you are breastfeeding, pregnant, or intend to become pregnant. 

Uses of Presto-ES Injection

Gastroesophageal reflux disease (GERD) and stomach ulcers.

Directions for Use

Presto-ES Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Presto-ES Injection contains esomeprazole which belongs to the class of drugs known as proton pump inhibitors used to treat gastroesophageal reflux disease (heartburn) and stomach ulcers caused by the use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). It is also used to reduce the risk of further ulcer bleeding following an endoscopy in adults. Presto-ES Injection works by irreversibly blocking the proton pump gate (which secretes stomach acid), thereby reducing stomach acid and treating acidity-related conditions.

Storage

Keep out of sight and reach of children.
Side effects of Presto-ES Injection
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.

Drug Warnings

You should avoid taking Presto-ES Injection if you are allergic to any of its components, other proton pump inhibitors or if you are taking certain HIV medications such as nelfinavir. Keep your doctor informed about your health condition and all the medicines you take to rule out any side effects/interactions. Consult your doctor if you are a pregnant woman/nursing mother. Let your doctor know if you have liver/kidney problems or if you are due to undergo Chromogranin A test. Taking Presto-ES Injection for more than a year may modestly raise your risk of hip, wrist, or spine fracture. If you use corticosteroids (which can increase the risk of osteoporosis) or have osteoporosis, tell your doctor.

Drug-Drug Interactions

verifiedApollotooltip
EsomeprazoleRilpivirine
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows. Instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid alcohol and smoking. Alcohol can raise the production of stomach acid leading to heartburn and acid reflux. On the other hand, smoking damages the sphincter, which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre-containing foods, berries, cherries, leafy green vegetables (kale, spinach) and black peppers in your meal. These foods are full of antioxidants, calcium and vitamin B 12 that can help cope with the long-term effects of the medicine.
  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H pyroli infection.
  • Avoid sitting continuously as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Presto-ES Injection impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach, thereby helps treat GERD.

No. Gas and acidity are two different conditions. Acidity is caused due to improper functioning of the valve (sphincter) located at the junction of the stomach and food pipe. As a result, stomach acid backflows and enters the upper part of the food pipe, causing heartburn. On the other hand, gas is the result of the digestion of food and drinks, eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc., from the body.

On long-term treatment, Presto-ES Injection may cause low magnesium levels. Low magnesium levels can make you tired, confused, and dizzy and cause muscle cramps, shakiness, and an irregular heartbeat. Inform the doctor if you experience any of these symptoms.

Presto-ES Injection may alter certain medical tests like secretin stimulation tests and urine screening tests for tetrahydrocannabinol (THC). So, if you are undergoing diagnostic tests inform your doctor that you are taking Presto-ES Injection.

Presto-ES Injection may slightly increase the risk of hip, wrist, or spine fracture, especially if you take it for longer than a year. Let your doctor know if you have osteoporosis or are taking corticosteroids (which can increase the risk of osteoporosis).

Drug-Drug Interactions Checker List

  • CLOPIDOGREL
  • WARFARIN
  • ATAZANAVIR
  • NELFINAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERLOTINIB
  • METHOTREXATE
  • DIAZEPAM
  • CILOSTAZOL
  • CISAPRIDE
  • DIGOXIN
  • CITALOPRAM
  • IMIPRAMINE
  • PHENYTOIN
  • TACROLIMUS
  • RIFAMPICIN
  • ST JOHN'S WORT

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): Gastroesophageal reflux disease (GERD) is a condition in which stomach acid flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. GERD symptoms include chest pain, difficulty swallowing, regurgitation (expulsion of food from the pharynx or oesophagus) of food/sour fluids, and a burning sensation in the chest.

Stomach ulcers: Stomach ulcers are sores (small, shallow wounds) that form on the lining of the stomach as a result of erosion of the stomach's protective coating. Symptoms include nausea, changes in appetite, bloody or dark faeces, unexplained weight loss, vomiting, and indigestion. If the ulcer is not treated, it can cause internal bleeding, peritonitis (inflammation of the abdominal wall), and pyloric stenosis (obstruction of the gastric outlet).

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