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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Prethromb-10Mg Tablet

Prethromb-10Mg Tablet belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of having a heart attack, or stroke in future. Prethromb-10Mg Tablet is prescribed after a heart attack, unstable angina, or if you have been treated with a procedure to open blocked arteries or have stents to open blocked/narrowed arteries. 

Prethromb-10Mg Tablet contains 'Prasugrel' which works by inhibiting the clumping of platelets, thereby reducing the chance of having blood clot formation. This results in lower cardiovascular events like myocardial infarction (heart attack) or stroke in future, especially in people who have had heart surgery known as angioplasty.

You are advised to take Prethromb-10Mg Tablet for as long as your doctor has prescribed it for you depending upon your medical consition. In some cases, Prethromb-10Mg Tablet may cause side-effects such as nose bleeds, skin rash, bleeding in the bowels, blood in urine, low haemoglobin, purpura (blood leakage under the skin), indigestion and bruising. You are advised to talk to your doctor if you experience these side-effects persistently.

Do not take Prethromb-10Mg Tablet if you ever had a brain stroke, bleeding in the brain or transient ischemic attack (stroke). Talk to your doctor before taking Prethromb-10Mg Tablet if you weigh below 60 kg, are 75 years or older, have/had a recent severe injury or surgery due to risk of severe bleeding problems. Consult your doctor if you are pregnant or breastfeeding. Prethromb-10Mg Tablet is not recommended for children as efficacy and safety have not been established. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

PRASUGREL-10MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Prethromb-10Mg Tablet

Prevention of Blood clot, Prevention of Heart attack, Prevention of Stroke

Medicinal Benefits

Prethromb-10Mg Tablet belongs to the group of medicines called antiplatelet agents used to prevent the formation of blood clots. Prethromb-10Mg Tablet helps in reducing the chance of having another heart attack or stroke. Prethromb-10Mg Tablet inhibits platelet aggregation and activation through irreversible binding of its active metabolite to the receptors. Prethromb-10Mg Tablet works by inhibiting the clumping of platelets, thereby reduces the chance of blood clot formation. This helps in reducing the rate of cardiovascular events such as myocardial infarction (heart attack) or stroke especially in people who have had heart surgery known as angioplasty.

Side Effects of Prethromb-10Mg Tablet

  • Nose bleeds
  • Skin rash
  • Bleeding in bowels
  • Blood in urine
  • Low haemoglobin
  • Purpura (blood leakage under the skin)
  • Indigestion
  • Bruising

Directions for Use

Swallow Prethromb-10Mg Tablet as a whole with a glass of water. Do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Prethromb-10Mg Tablet if you are allergic to any of its contents, if you have a medical condition that causes bleeding from the stomach or intestine, had a transient ischemic attack (stroke) or if you are suffering from severe liver disease. Talk to your doctor before taking Prethromb-10Mg Tablet if you have bleeding problems, weigh below 60 kg, are 75 years or older, had/have a recent serious injury or surgery, kidney or liver disease. Consult your doctor immediately if you develop a medical condition called thrombotic thrombocytopenic purpura (blood disorder) while taking Prethromb-10Mg Tablet; its symptoms include fever, bruising under the skin which appears as red pinpoint dots, with/without unexplained confusion, tiredness and yellowing of skin and eyes. Consult your doctor if you are pregnant or breastfeeding. Prethromb-10Mg Tablet is not recommended for children as the efficacy and safety have not been established. People affected with active pathological bleeding (peptic ulcer, intracranial or brain haemorrhage) and history of stroke or transient ischemic attack (TIA) should not take Prethromb-10Mg Tablet.

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Drug-Drug Interactions

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PrasugrelMifepristone
Critical
PrasugrelAnistreplase
Severe

Drug-Drug Interactions

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PrasugrelMifepristone
Critical
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Mifepristone with Prethromb-10Mg Tablet can increase the chance of experiencing vaginal bleeding in women.

How to manage the interaction:
Taking Prethromb-10Mg Tablet with Mifepristone can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience prolonged, heavy bleeding, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.
PrasugrelAnistreplase
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Prethromb-10Mg Tablet with Anistreplase can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Co-administration of Prethromb-10Mg Tablet with Anistreplase can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelDrotrecogin alfa (activated)
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Prethromb-10Mg Tablet with Drotrecogin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Prethromb-10Mg Tablet and Drotrecogin alfa (activated), you can take these medicines together if prescribed by your doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelLepirudin
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Prethromb-10Mg Tablet with Lepirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Prethromb-10Mg Tablet and Lepirudin, you can take these medicines together if prescribed by your doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelApixaban
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Apixaban with Prethromb-10Mg Tablet can lower the levels of Apixaban which can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Apixaban with Prethromb-10Mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
PrasugrelAcalabrutinib
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Prethromb-10Mg Tablet with Acalabrutinib can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Prethromb-10Mg Tablet with Acalabrutinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelReteplase
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Taking Prethromb-10Mg Tablet with Reteplase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prethromb-10Mg Tablet with Reteplase can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelAnagrelide
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Anagrelide with Prethromb-10Mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Taking Prethromb-10Mg Tablet with Anagrelide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelEptifibatide
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Eptifibatide with Prethromb-10Mg Tablet can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Prethromb-10Mg Tablet with Eptifibatide can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
PrasugrelSulindac
Severe
How does the drug interact with Prethromb-10Mg Tablet:
Co-administration of Sulindac with Prethromb-10Mg Tablet can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although there is a possible interaction between Prethromb-10Mg Tablet and Sulindac, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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PRASUGREL-10MGHerbal products/medicines

Drug-Food Interactions

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PRASUGREL-10MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill, Aloevera, Cannabis

How to manage the interaction:
Taking herbs during treatment with Prethromb-10Mg Tablet may lead to an interaction. Avoid herbs like garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during treatment with Prethromb-10Mg Tablet.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • HYDROCODONE
  • TRAMADOL
  • CLOPIDOGREL
  • ENOXAPARIN
  • RIVAROXABAN
  • WARFARIN
  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • TICAGRELOR

Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Special Advise

Regular haemoglobin and hematocrit diagnostic tests are recommended if you are taking Prethromb-10Mg Tablet.

Author Details

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Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot, thereby prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow which could lead to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

Prethromb-10Mg Tablet Substitute

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