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Composition :

PRIMAQUINE-7.5MG

Manufacturer/Marketer :

Zenlabs Ethica Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

About Primaquine 7.5 Tablet

Primaquine 7.5 Tablet belongs to the class 'anti-malarials' primarily used for the treatment of malaria. A disease caused by a plasmodium parasite, transmitted by the bite of infected mosquitoes. The severity of malaria varies based on the species of plasmodium. Symptoms are chills, fever and sweating, usually occurring a few weeks after being bitten. People travelling to areas where malaria is common typically take protective drugs before, during and after their trip. 

Primaquine 7.5 Tablet contains 'primaquine'. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Primaquine 7.5 Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite.

Primaquine 7.5 Tablet should be taken as prescribed by your doctor, preferably with a meal to avoid stomach upset and at fixed intervals every day for best results. The dose of Primaquine 7.5 Tablet can vary depending upon your condition and the severity of the infection. It is recommended to complete medicine and take this medicine as prescribed by your doctor before visiting a malaria-prone area. The common side effects of Primaquine 7.5 Tablet include rash, vomiting, headache, dizziness, hives, stomach pain, nausea, abdominal pain, itching, heartburn, gastrointestinal discomfort, upper abdominal pain. Everyone need not experience the above side effects. In case of any discomfort, stop the medicine and speak with your doctor.

Before starting Primaquine 7.5 Tablet , please inform your doctor if you are allergic to Primaquine 7.5 Tablet . Do not take Primaquine 7.5 Tablet on your own. Primaquine 7.5 Tablet is used in caution with Pregnant/breast-feeding mother. Primaquine 7.5 Tablet is not recommended in patients with heart disease, liver, kidney problems and rheumatoid-arthritis.

Uses of Primaquine 7.5 Tablet

Malaria.

Directions for Use

Take it with food to decrease the risk of stomach upset. Swallow it as a whole. Do not chew, crush or break it. Do not skip any doses and finish the full course of treatment even if you feel better.

Key Benefits

Primaquine 7.5 Tablet belongs to the class 'anti-malarials' primarily used for the treatment of malaria. Primaquine 7.5 Tablet contains 'primaquine'. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Primaquine 7.5 Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite. Primaquine 7.5 Tablet  can also be given in combination with clindamycin for the treatment of Pneumocystis carinii pneumonia (PCP).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before starting Primaquine 7.5 Tablet , please inform your doctor if you are allergic to Primaquine 7.5 Tablet . Do not take Primaquine 7.5 Tablet on your own. Primaquine 7.5 Tablet is used in caution with Pregnant/breast-feeding mother. Primaquine 7.5 Tablet is not recommended in patients of heart disease, liver, kidney problems and rheumatoid arthritis. Primaquine 7.5 Tablet is not recommended in patients of diabetes. Primaquine 7.5 Tablet  is not recommended for use in acutely ill patients suffering from a systemic disease like rheumatoid arthritis and lupus erythematosus. There is a marked decrease in the number of granulocytes in such conditions. Primaquine 7.5 Tablet is also not recommended for use if you are receiving a medication that can cause anaemia or suppression of the immune system by affecting bone marrow cells as a side effect. Medicine is not recommended for use if you are consuming Quinacrine or any other combination medicine containing quinacrine (anti-malarial drug). Patients should avoid pregnancy during treatment. It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so might result in drug resistance. Sexually active women can take effective Contraceptive pills and men should use a condom during and 3months after stopping the treatment. Primaquine 7.5 Tablet should be discontinued immediately when leukopenia (reduced white blood cells) occurs.

Diet & Lifestyle Advise

  • Adequate nutrition is the key to improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover
  • Avoid eating fried and processed foods, junk oily and spicy foods can aggravate nausea and can disturb the digestion process in the body.
  • High fibre foods like whole-grain cereals must be avoided by malaria patients. Instead, the intake of fruits and pulses should be increased as they provide adequate nutrition

Side Effects of Primaquine 7.5 Tablet

  • Rash
  • Vomiting
  • Headache
  • Stomach pain
  • Dizziness
  • Lightheadedness
  • Hives
  • Dark-coloured urine
  • Abdominal pain
  • Confusion
  • Weakness
  • Itching
  • Heartburn
  • Nausea
  • Gastrointestinal discomfort
  • Upper abdominal pain

Habit Forming

No

Therapeutic Class

[ANTI- MALARIALS]

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FAQs

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • ASPIRIN
  • PYRIMETHAMINE
  • TRIMETHOPRIM
  • PENICILLAMINE
  • PHENYTOIN
  • DEXAMETHASONE
  • CHOLECALCIFEROL
  • ASCORBIC ACID
  • RIBOFLAVIN (VITB2)
  • PYRIDOXINE (VITB6)
  • VALPROIC ACID
  • ACETAMINOPHEN

Special Advise

  • Always take Primaquine 7.5 Tablet with meals for reduced gastric irritation.
  • Eye examination prior to and at 3–6 monthly intervals during use is required if patients are receiving Primaquine at continuous high doses for a longer duration.
  • It may cause low blood sugar level. Monitor your blood sugar level regularly, if you are diabetic.
  • When Primaquine 7.5 Tablet used long term, your doctor may monitor the amounts of the different types of blood cells in your blood regularly.

Disease/Condition Glossary

Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure and jaundice because of excessive red blood cell death due to plasmodium growth inside them.

Have a query?

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Alcohol

Safe if prescribed

Interaction of Primaquine 7.5 Tablet with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Consult your doctor

Primaquine 7.5 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations, if the benefits are more than the potential risks. Please consult your doctor.

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Breast Feeding

Consult your doctor

Primaquine 7.5 Tablet is recommended for use in breastfeeding women only after diagnostic tests are performed to confirm normal G6PD enzyme levels. Consult your doctor before using this medicine

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Driving

Safe if prescribed

Primaquine 7.5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Consult your doctor

Primaquine 7.5 Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Primaquine 7.5 Tablet

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Kidney

Consult your doctor

Primaquine 7.5 Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Primaquine 7.5 Tablet .

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Children

Safe if prescribed

Safe to use in children (<12) yet dose adjustment by a doctor will be done on the basis of age, weight and severity of the infection.

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