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Composition :

ESTRADIOL-2MG

Manufacturer/Marketer :

Bayer Zydus Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Progynova 2 mg Tablet

Progynova 2 mg Tablet contains a semi-synthetic female hormone Estradiol, indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. Progynova 2 mg Tablet is prescribed when the body is not producing a sufficient amount of natural estrogen.

Progynova 2 mg Tablet contains estradiol which regulates the menstrual cycle and ovulation. Progynova 2 mg Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. 

You are advised to take Progynova 2 mg Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience headache, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Progynova 2 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Progynova 2 mg Tablet . While taking Progynova 2 mg Tablet , your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Progynova 2 mg Tablet . 

Uses of Progynova 2 mg Tablet

Hormonal replacement therapy, Hypoestrogenism (estrogen deficiency), Osteoporosis (thinning of bones), Symptoms associated with menopause (itching, dryness in vagina, hot flushes)

Directions for Use

Swallow Progynova 2 mg Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Progynova 2 mg Tablet contains a synthetic female hormone that regulates ovulation and menstruation in women. Progynova 2 mg Tablet is given as a hormone replacement therapy for estrogen. It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Progynova 2 mg Tablet
  • Mild physical activity can increase blood flow and lessen pain from tense or irritated muscles.
  • Pain might be reduced with a supportive, properly fitting bra, particularly when exercising.
  • Limit or stay away from items that can cause breast pain, like spicy and caffeine-containing foods.
  • vitamin E medication which could ease breast pain and encourage rest.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Wash the vulva with warm water and a mild, unscented soap, avoiding harsh soaps or scrubbing.
  • Do not douche as it can disrupt the natural balance of bacteria in the vagina.
  • After bathing, pat the vulva completely dry with a soft towel.
  • Wear loose-fitting cotton underwear to allow air circulation.
  • Change wet or sweaty clothing regularly.
  • Avoid using scented products like feminine hygiene sprays, lotions, and toilet paper.
  • Wear loose-fitting pants and skirts.
  • Stress can increase itching, so practice relaxation techniques like meditation and yoga.

Drug Warnings

Do not take Progynova 2 mg Tablet if you are allergic to any of its ingredients. Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure, if you are pregnant or breastfeeding. Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Progynova 2 mg Tablet . Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Progynova 2 mg Tablet . 

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolLenalidomide
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Progynova 2 mg Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Progynova 2 mg Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolLenalidomide
Severe
How does the drug interact with Progynova 2 mg Tablet:
Coadministration of Progynova 2 mg Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Progynova 2 mg Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolClindamycin
Severe
How does the drug interact with Progynova 2 mg Tablet:
When taken in combination, clindamycin can lower the amount or action of Progynova 2 mg Tablet.

How to manage the interaction:
Co-administration of Progynova 2 mg Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolDantrolene
Severe
How does the drug interact with Progynova 2 mg Tablet:
The usage of Progynova 2 mg Tablet with dantrolene might have significant adverse effects on your liver.

How to manage the interaction:
Taking Progynova 2 mg Tablet with Dantrolene together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have a fever, chills, joint pain or swelling, severe fatigue or weakness, unusual bleeding or bruising, skin rash or itching, lack of appetite, nausea, vomiting, or yellowing of the skin or whites of your eyes, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolTranexamic acid
Severe
How does the drug interact with Progynova 2 mg Tablet:
Co-administration of Progynova 2 mg Tablet with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Progynova 2 mg Tablet with Tranexamic acid can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolExemestane
Severe
How does the drug interact with Progynova 2 mg Tablet:
Using Progynova 2 mg Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Progynova 2 mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolThalidomide
Severe
How does the drug interact with Progynova 2 mg Tablet:
Taking thalidomide together with Progynova 2 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Progynova 2 mg Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolLetrozole
Severe
How does the drug interact with Progynova 2 mg Tablet:
Letrozole may have a negative effect when used with Progynova 2 mg Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Progynova 2 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Progynova 2 mg Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Progynova 2 mg Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Progynova 2 mg Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolPomalidomide
Severe
How does the drug interact with Progynova 2 mg Tablet:
Co-administration of Progynova 2 mg Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Progynova 2 mg Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The rate of absorption of oral estrogens may be increased by coadministration with grapefruit juice. Avoid or restrict the consumption of grapefruit juice while taking Progynova 2 mg Tablet.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flashes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flashes and night sweats. Take minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Progynova 2 mg Tablet Substitute

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Progynova 2 mg Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

Do not use Progynova 2 mg Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have/had any cancer (breast or uterus cancer), or undergoing any other estrogen treatment. Tell your doctor if you had a heart attack, stroke, blood clot, or liver problems, if you are pregnant, breastfeeding, or planning to get pregnant.

No, Progynova 2 mg Tablet should not be taken if you are undergoing surgery. You should inform your doctor, and he might ask you to stop hormone replacement therapy about 4 to 6 weeks before surgery to reduce the risk of blood clots.

Progynova 2 mg Tablet may cause either weight gain or weight loss. It is a common side effect of Progynova 2 mg Tablet . Regular exercise and eating a healthy diet can help prevent weight gain.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • GRISEOFULVIN
  • RIFAMPICIN
  • RITONAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • BOSENTAN
  • ASPIRIN

Disease/Condition Glossary

Hypoestrogenism: It refers to the lowered secretion of the natural female sex hormone known as estrogen. It is an umbrella term used for estrogen deficiency in various conditions. Its abnormalities may lead to infertility, bone loss, and lipid abnormalities.

Osteoporosis: Osteoporosis means the bone has become porous. It is a disease in which too much bone is lost, and the body makes relatively little bone. As a result, bones become weak and can break easily if you fall.

Hormone replacement therapy (HRT): It is a treatment to relieve symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.

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