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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About PROMISTIN 1MILLION IU INJECTION

PROMISTIN 1MILLION IU INJECTION belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. PROMISTIN 1MILLION IU INJECTION does not work against infections caused by a virus.

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor. You are advised to take PROMISTIN 1MILLION IU INJECTION for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of PROMISTIN 1MILLION IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly.

Uses of PROMISTIN 1MILLION IU INJECTION

Several bacterial infections

Directions for Use

PROMISTIN 1MILLION IU INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. PROMISTIN 1MILLION IU INJECTION binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. PROMISTIN 1MILLION IU INJECTION is used when other antibiotics are not suitable.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PROMISTIN 1MILLION IU INJECTION

  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

Drug Warnings

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly. Inform your anesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor for effective results.

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
ColistinKanamycin
Severe

Drug-Drug Interactions

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ColistinBCG vaccine
Critical
How does the drug interact with Promistin 1million Iu Injection:
Coadministration of Promistin 1million Iu Injection along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking Promistin 1million Iu Injection with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinKanamycin
Severe
How does the drug interact with Promistin 1million Iu Injection:
Coadministration of Promistin 1million Iu Injection with Kanamycin can increase the level and risk of Promistin 1million Iu Injection side effects.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Kanamycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinAtracurium
Severe
How does the drug interact with Promistin 1million Iu Injection:
Coadministration of Atracurium with Promistin 1million Iu Injection can increase the risk of Atracurium side effects.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Atracurium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, slurred speech, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinPipecuronium bromide
Severe
How does the drug interact with Promistin 1million Iu Injection:
Coadministration of Pipecuronium bromide with Promistin 1million Iu Injection may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and pipecuronium bromide, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinPancuronium
Severe
How does the drug interact with Promistin 1million Iu Injection:
Using Pancuronium with Promistin 1million Iu Injection can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinTenofovir alafenamide
Severe
How does the drug interact with Promistin 1million Iu Injection:
Combining Promistin 1million Iu Injection with Tenofovir alafenamide may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Tenofovir alafenamide, you can take these medicines together if prescribed by your doctor. However, consult a doctor if you experience an upset stomach, rash, dizziness, or fever. Do not stop using any medications without a doctor's advice.
ColistinAdefovir dipivoxil
Severe
How does the drug interact with Promistin 1million Iu Injection:
Combining Promistin 1million Iu Injection with Adefovir dipivoxil may decrease Promistin 1million Iu Injection's excretion rate, which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Adefovir dipivoxil, you can take these medicines together if prescribed by your doctor. However, if you experience any irregular urination, swelling, shortness of breath, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinIohexol
Severe
How does the drug interact with Promistin 1million Iu Injection:
Combining Promistin 1million Iu Injection with Iohexol can increase the effect or side effects of Iohexol.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Iohexol, you can take these medicines if prescribed by your doctor. However, if you experience vomiting, loss of appetite, irregular urination, swelling, shortness of breath, muscle cramps, or weakness, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinEverolimus
Severe
How does the drug interact with Promistin 1million Iu Injection:
Coadministration of Promistin 1million Iu Injection with Everolimus can increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction between Promistin 1million Iu Injection and Everolimus, it can be taken if prescribed by a doctor. However, if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, or weakness, consult a doctor. Do not discontinue any medications without consulting a doctor.
ColistinHuman immunoglobulin
Severe
How does the drug interact with Promistin 1million Iu Injection:
Taking Human immunoglobulin with Promistin 1million Iu Injection, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Promistin 1million Iu Injection, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of PROMISTIN 1MILLION IU INJECTION to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking PROMISTIN 1MILLION IU INJECTION.
  • Avoid alcohol consumption as it may increase adverse effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMIKACIN
  • NETILIMICIN
  • TOBRAMYCIN
  • GENTAMICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN

Special Advise

  • Regular blood tests are recommended to monitor the levels of PROMISTIN 1MILLION IU INJECTION in blood and kidney functioning.
  • Inform your anaesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anaesthesia.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grows in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have cell wall). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness.

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