PRONATE F TABLET 10'S
MRP ₹121
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₹18.1 Cashback (15%)
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About PRONATE F TABLET
PRONATE F TABLET belongs to the class of 'anti-migraine drugs' primarily used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.
PRONATE F TABLET consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It is also used to treat vertigo (spinning sensation).
Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of PRONATE F TABLET include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting PRONATE F TABLET . PRONATE F TABLET may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking PRONATE F TABLET if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with PRONATE F TABLET as it could lead to increased drowsiness.
Uses of PRONATE F TABLET
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Directions for Use
Key Benefits
PRONATE F TABLET is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine.
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- If you experience a persistent cough after taking medication, consult your doctor to determine the best course of action.
- Your doctor will assess and adjust your medication regimen if necessary to minimize the cough.
- Your doctor may recommend cough medications, such as expectorants, to help loosen and clear mucus.
- Stay hydrated by drinking plenty of fluids, and consider a soothing lifestyle, such as a warm, humid environment, avoiding irritants like smoke and dust, and getting plenty of rest.
- If your cough persists or worsens, follow up with your doctor for further evaluation and treatment.
- Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
- Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
- Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
- Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
- Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
- Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
- Restlessness is related to mental health and needs medical attention if it's severe.
- Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
- Prevent smoking as it can impact your calmness of body and mind.
- Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
- Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
- Keep regular sleeping hours.
- Don’t consume nicotine, caffeine, or alcohol in the hours leading up to bed.
- Practice relaxation exercises before bedtime.
- Regular physical activity can promote deeper and better sleep. However, avoid intense exercise within 2-3 hours of bedtime, as it can disrupt your sleep.
- If nightmares continue, cognitive behavioral therapy (CBT) may be a helpful treatment option. Your doctor may recommend CBT to address underlying issues and provide coping strategies to manage nightmares.
Drug Warnings
Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting PRONATE F TABLET . Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you PRONATE F TABLET . Avoid consuming alcohol along with PRONATE F TABLET as it could lead to increased dizziness and drowsiness.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of thioridazine with Pronate F Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.
How to manage the interaction:
Although there is an interaction between Pronate F Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Taking atenolol and Pronate F Tablet together may lower your blood pressure excessively which may lead to side effects.
How to manage the interaction:
Combined use of atenolol and Pronate F Tablet may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Using Pronate F Tablet together with salmeterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pronate F Tablet can sometimes cause breathing problems.
How to manage the interaction:
Although taking Pronate F Tablet together with Salmeterol can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Co-administration of Epinephrine with Pronate F Tablet may cause severe high blood pressure and reduced heart rate.
How to manage the interaction:
Taking Epinephrine with Pronate F Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Coadministration of Pronate F Tablet and levosalbutamol can increase the risk of breathing problems.
How to manage the interaction:
Although there is an interaction between Pronate F Tablet and levosalbutamol, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Using Pronate F Tablet together with isoetharine may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pronate F Tablet can sometimes cause breathing problems.
How to manage the interaction:
Although taking Pronate F Tablet together with Isoetarine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Coadministration of rivastigmine with Pronate F Tablet can cause an abnormally slow heart rate and low blood pressure.
How to manage the interaction:
Although taking Pronate F Tablet together with Rivastigmine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.
Using Pronate F Tablet and salbutamol together can reduce the effects or increase the risk of narrowing of the airways.
How to manage the interaction:
The combined use of Pronate F Tablet and salbutamol can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Using Pronate F Tablet together with Theophylline makes the Pronate F Tablet less effective in controlling blood pressure, and it also increases the effects of theophylline
How to manage the interaction:
Although taking Pronate F Tablet together with Theophylline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience nausea, vomiting, sleeplessness, tremors, restlessness, irregular heartbeats, or difficulty breathing. Do not stop using any medication without consulting a doctor.
Combining ceritinib with Pronate F Tablet can decrease heart rate and increase the risk of an irregular heart rhythm.
How to manage the interaction:
Although taking Posaconazole together with Ceritinib can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, generalized weakness, dizziness, or shortness of breath, consult a doctor immediately. Do not stop using any medications consulting a doctor.
Drug-Food Interactions
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Diet & Lifestyle Advise
- Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to PRONATE F TABLET .
- Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
- You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
- Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
- Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
- You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
- Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.
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Alcohol
Safe if prescribed
You are recommended to avoid alcohol consumption while taking PRONATE F TABLET . Alcohol intake, along with PRONATE F TABLET , may cause increased dizziness and drowsiness.
Pregnancy
Consult your doctor
Please consult your doctor if you are pregnant or planning to conceive before using PRONATE F TABLET .
Breast Feeding
Consult your doctor
Please consult your doctor before taking PRONATE F TABLET if you are a lactating mother.
Driving
Safe if prescribed
PRONATE F TABLET may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.
Liver
Consult your doctor
Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.
Kidney
Consult your doctor
Plasma clearance of Propranolol in PRONATE F TABLET is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.
Children
Safe if prescribed
PRONATE F TABLET is safe to use for children below 12 years of age when prescribed by the doctor.
FAQs
PRONATE F TABLET is a combination of two drugs: Propranolol and Flunarizine. PRONATE F TABLET treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.
PRONATE F TABLET may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.
PRONATE F TABLET does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.
PRONATE F TABLET is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting PRONATE F TABLET if you have a medical history.
Your doctor will prescribe PRONATE F TABLET to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. PRONATE F TABLET also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using PRONATE F TABLET unless advised by your doctor.
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Reference
- https://www.drugs.com/dosage/propranolol.html
- http://ahckids.org/wp-content/uploads/2015/02/SibeliumInsert.pdf
- https://ijpsr.com/bft-article/formulation-evaluation-and-estimation-of-propranolol-hydrochloride-and-flunarizine-dihydrochloride-conventional-tablets-in-combined-dosage-form-and-its-comparison-with-marketed-formulations/?view=fulltext
- https://pubchem.ncbi.nlm.nih.gov/compound/Propranolol#section=Drug-and-Medication-Information
- https://www.gosh.nhs.uk/medical-information-0/search-medical-conditions/medicines-information/flunarizine-prevent-migraine
