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  1. Home
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  3. PRONATE F TABLET 10'S

PRONATE F TABLET 10'S, Pack of 10
PRONATE F TABLET 10'S, Pack of 10
PRONATE F TABLET 10'S, Pack of 10
Non returnable*
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Whats That

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Composition :

FLUNARIZINE-10MG + PROPRANOLOL-40MG

Manufacturer/Marketer :

Linux Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About PRONATE F TABLET

PRONATE F TABLET belongs to the class of 'anti-migraine drugs' primarily used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

PRONATE F TABLET consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of PRONATE F TABLET include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting PRONATE F TABLET . PRONATE F TABLET may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking PRONATE F TABLET if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with PRONATE F TABLET as it could lead to increased drowsiness.

Uses of PRONATE F TABLET

Migraine.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, crush or break it.

Medicinal Benefits

PRONATE F TABLET is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting PRONATE F TABLET . Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you PRONATE F TABLET . Avoid consuming alcohol along with PRONATE F TABLET as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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PropranololThioridazine
Critical
PropranololTizanidine
Severe

Drug-Drug Interactions

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PropranololThioridazine
Critical
How does the drug interact with Pronate F Tablet:
Coadministration of thioridazine with Pronate F Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Pronate F Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololTizanidine
Severe
How does the drug interact with Pronate F Tablet:
Coadministration of tizanidine and Pronate F Tablet may further lower your blood pressure due to the additive effect.

How to manage the interaction:
Although taking Pronate F Tablet together with Tizanidine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience headache, dizziness, lightheadedness, fainting, and/or changes in heart rate. Do not stop taking any medication without consulting your doctor.
PropranololDisopyramide
Severe
How does the drug interact with Pronate F Tablet:
Taking Pronate F Tablet and disopyramide together can enhance the effects of disopyramide.

How to manage the interaction:
Although there may be an interaction, disopyramide can be taken with Pronate F Tablet if prescribed by your doctor. However, consult your doctor if you experience dizziness, fainting, palpitations, or slow or fast heart rate, consult your doctor immediately. Do not stop using any medications without consulting your doctor.
PropranololIndacaterol
Severe
How does the drug interact with Pronate F Tablet:
Using Pronate F Tablet together with indacaterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pronate F Tablet can cause breathing problems.

How to manage the interaction:
Although taking Pronate F Tablet together with Indacaterol can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololFingolimod
Severe
How does the drug interact with Pronate F Tablet:
Using fingolimod with Pronate F Tablet can cause an excessive lowering of heart rate and can lead to other heart problems.

How to manage the interaction:
Although taking Pronate F Tablet together with Fingolimod can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations. Do not stop using any medicines without consulting a doctor.
PropranololIsoetarine
Severe
How does the drug interact with Pronate F Tablet:
Using Pronate F Tablet together with isoetharine may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pronate F Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Pronate F Tablet together with Isoetarine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololSalmeterol
Severe
How does the drug interact with Pronate F Tablet:
Using Pronate F Tablet together with salmeterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Pronate F Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Pronate F Tablet together with Salmeterol can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololRivastigmine
Severe
How does the drug interact with Pronate F Tablet:
Coadministration of rivastigmine with Pronate F Tablet can cause an abnormally slow heart rate and low blood pressure.

How to manage the interaction:
Although taking Pronate F Tablet together with Rivastigmine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, dizziness, fainting, or irregular heartbeat. Do not discontinue any medicine without consulting a doctor.
PropranololAtenolol
Severe
How does the drug interact with Pronate F Tablet:
Taking atenolol and Pronate F Tablet together may lower your blood pressure excessively which may lead to side effects.

How to manage the interaction:
Combined use of atenolol and Pronate F Tablet may result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololEpinephrine
Severe
How does the drug interact with Pronate F Tablet:
Co-administration of Epinephrine with Pronate F Tablet may cause severe high blood pressure and reduced heart rate.

How to manage the interaction:
Taking Epinephrine with Pronate F Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to PRONATE F TABLET .
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

PRONATE F TABLET Substitute

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Author Details

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Written By

Divya L

PharmaD

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

PRONATE F TABLET is a combination of two drugs: Propranolol and Flunarizine. PRONATE F TABLET treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

PRONATE F TABLET may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

PRONATE F TABLET does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

PRONATE F TABLET is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting PRONATE F TABLET if you have a medical history.

Your doctor will prescribe PRONATE F TABLET to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. PRONATE F TABLET also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using PRONATE F TABLET unless advised by your doctor.

Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • QUETIAPINE
  • ARIPIPRAZOLE
  • ZOLPIDEM
  • DIPHENHYDRAMINE
  • SERTRALINE
  • DULOXETINE
  • FLUOXETINE
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

  • Let your doctor know that you are taking PRONATE F TABLET if you are undergoing any medical tests.
  • Beta-blockers like Propranolol can mask hypoglycaemia symptoms (low blood sugar) or hyperthyroidism (high thyroid levels).
  • It is advised to inform your doctor if you have diabetes or thyroid disease before using PRONATE F TABLET .
  • Beta-blockers can also cause changes in serum lipid profiles. Patients with pre-existing hyperlipidaemia (high lipid levels) should be closely monitored if using PRONATE F TABLET .

Disease/Condition Glossary

Migraine: It is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Symptoms of migraine may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound. Migraine can be triggered by various factors like foods (eggs, tomatoes, onions, dairy products, wheat, pasta, citrus fruits, nitrites found in foods, alcohol, and red wine), hormonal changes, sleep changes, stress, loud noises, and medications.

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