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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Proxym-XT Tablet

Proxym-XT Tablet belongs to the class of medications called ‘analgesics’ used to treat pain associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, etc. Osteoarthritis is a degenerative bone disease in which the tissue supporting the joints wears down. Rheumatoid arthritis is a condition in which the immune system attacks its own tissue leading to joint pain and inflammation. Ankylosing spondylitis is the inflammation of the spine and large joints.

Proxym-XT Tablet contains Etodolac and Paracetamol. Etodolac is a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol is an analgesic. They act by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation. The inhibition of these substances can cause a decrease in symptoms such as pain, joint stiffness, and tenderness.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Proxym-XT Tablet are nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, dizziness, headache, tiredness, rash, ringing in your ears, clay or black-colored stools, and increased heartbeat. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

It is not recommended to take Proxym-XT Tablet if you are allergic to any contents of it. Proxym-XT Tablet should not be used in patients with a history of ulcers in the stomach or intestine, have had an allergic reaction to NSAIDs have severe liver, kidney, heart failure, and alcoholic liver disease. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly patients. It is not advised to consume alcohol as it may increase the risk of stomach bleeding. Proxym-XT Tablet may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Proxym-XT Tablet

Pain associated with Osteoarthritis, Rheumatoid arthritis, and Ankylosing spondylitis, etc.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Proxym-XT Tablet is used in the treatment of pain, swelling, and inflammation associated with chronic (long-term) conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. It contains Etodolac and Paracetamol. It acts by blocking the production of chemical substances called prostaglandins that cause pain, swelling, and inflammation.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Proxym-XT Tablet , inform your doctor if you have high blood pressure, high cholesterol, diabetes, heart disease, heart attack or stroke, blood clot, stomach bleeding, asthma, edema (fluid overload), smoking habit, and liver, kidney disease. Inform your doctor immediately if you cough up or vomit blood or notice black or tarry stools, as it can be a sign of stomach bleeding. Proxym-XT Tablet increases skin sensitivity to the sun, so avoid prolonged exposure to sunlight, sunlamps, and tanning beds.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Co-administration of Proxym-XT 200 mg/325 mg Tablet with Meloxicam can raise the adverse consequences in the digestive system, including inflammation, bleeding, ulceration, and, in rare cases, perforation(rupture).

How to manage the interaction:
Taking Meloxicam with Proxym-XT 200 mg/325 mg Tablet is not recommended can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Using ketorolac together with Proxym-XT 200 mg/325 mg Tablet may increase the risk of side effects in the gastrointestinal tract (inflammation, bleeding and ulceration).

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Ketorolac is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Co-administration of Proxym-XT 200 mg/325 mg Tablet with Prasugrel can increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Proxym-XT 200 mg/325 mg Tablet and Prasugrel together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Co-administration of Proxym-XT 200 mg/325 mg Tablet and Rivaroxaban can increase the risk of bleeding problems, including severe hemorrhage.

How to manage the interaction:
Co-administration of Proxym-XT 200 mg/325 mg Tablet and Rivaroxaban can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
The use of acalabrutinib in conjunction with Proxym-XT 200 mg/325 mg Tablet may raise the risk of bleeding. Treatment with acalabrutinib alone has been linked to severe haemorrhage.

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Acalabrutinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, a severe headache, and/or weakness, consult your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking Indomethacin with Proxym-XT 200 mg/325 mg Tablet can increase the risk of side effects (inflammation, bleeding, ulceration, and perforation of the stomach).

How to manage the interaction:
Although there is a possible interaction between Proxym-XT 200 mg/325 mg Tablet and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
When Proxym-XT 200 mg/325 mg Tablet is taken with Dabigatran etexilate may increase the risk or severity of bleeding and hemorrhage.

How to manage the interaction:
Taking Dabigatran etexilate with Proxym-XT 200 mg/325 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you happen to have any unusual bleeding or bruising, or other signs and symptoms of bleeding, such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Co-administration of methotrexate with Proxym-XT 200 mg/325 mg Tablet can increase the level and effects of methotrexate. This can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Proxym-XT 200 mg/325 mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
EtodolacDicoumarol
Severe
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
Taking Proxym-XT 200 mg/325 mg Tablet with dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Proxym-XT 200 mg/325 mg Tablet and Dicoumarol, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Proxym-XT 200 mg/325 mg Tablet:
When tolmetin is used with Proxym-XT 200 mg/325 mg Tablet, there is an increased risk of significant gastrointestinal toxicity (inflammation, bleeding, ulceration, and perforation).

How to manage the interaction:
Taking Proxym-XT 200 mg/325 mg Tablet with Tolmetin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on the treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
  • In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize levels of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible, and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel at the back of your spine curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Proxym-XT Tablet Substitute

Substitutes safety advice

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Proxym-XT Tablet contains Etodolac and Paracetamol. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) whereas Paracetamol is an analgesic. Proxym-XT Tablet acts by blocking the production of chemical substances called prostaglandins, that cause pain, swelling, and inflammation. The inhibition of these substances can cause a decrease in symptoms such as pain, joint stiffness, and tenderness.

The common side-effects of Proxym-XT Tablet are nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, dizziness, headache, tiredness, rash, ringing in your ears, and increased heartbeat. These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.

Proxym-XT Tablet should not be taken with aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aceclofenac. It may increase the risk of gastrointestinal (stomach and intestine) side-effects. In addition, do not take any over-the-counter (OTC) medicines without consulting a doctor as most of the OTC cold or pain medicines contain an NSAID.

Proxym-XT Tablet is usually well-tolerated in most of the patients. However, it should be used with caution in patients with high blood pressure and high cholesterol as it increases the risk of a heart attack in higher doses. So, inform your doctor about all the illnesses you have before taking this medicine.

Proxym-XT Tablet may cause a change in consistency and color of the stools. You may notice clay or black-colored stool while using this medicine. Consult a doctor if the condition persists.

Proxym-XT Tablet contains Etodolac and Paracetamol, which may cause liver damage when used in higher doses or longer durations. So, take this medicine for a dose and duration as intended by your doctor. Also, avoid alcohol intake while using this medicine, as alcohol may increase the risk of liver damage and stomach bleeding.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CYCLOSPORINE
  • METHOTREXATE
  • LITHIUM
  • PREDNISONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE

Special Advise

  • Do not take any over-the-counter (OTC) allergy or pain medicines without consulting your doctor. Most of these medicines contain an NSAID or analgesic (pain reliever), similar to Etodolac or Paracetamol present in Proxym-XT Tablet .
  • It may take up to 2 weeks to improve your symptoms. So, inform your doctor if your symptoms don’t improve within 2 weeks.
  • Your doctor may monitor liver and kidney function if Proxym-XT Tablet is prescribed for the long term.

Disease/Condition Glossary

Osteoarthritis: Osteoarthritis is the common type of arthritis in which the cartilage that cushions the bone's ends erodes due to wear and tear over time. Common symptoms are joint pain and stiffness.

Rheumatoid arthritis (RA): Rheumatoid arthritis (RA) is an autoimmune disease in which the immune cells attack the joints and cause bone erosion leading to severe pain and swelling. It may lead to joint deformity if left untreated.

Ankylosing spondylitis: Ankylosing spondylitis is a type of arthritis in which inflammation is seen in the spine and large joints. It led to pain and stiffness in the back and affected joints.

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