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Reviewed By Sunny S , MBBS
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Composition :

CYCLOSPORINE-100MG

Manufacturer/Marketer :

Rockmed Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Psortude-100 mg Softgel Capsule 5's

Psortude-100 mg Softgel Capsule 5's belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Psortude-100 mg Softgel Capsule 5's contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Psortude-100 mg Softgel Capsule 5's as prescribed. You are advised to take Psortude-100 mg Softgel Capsule 5's for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Psortude-100 mg Softgel Capsule 5's may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Psortude-100 mg Softgel Capsule 5's inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Psortude-100 mg Softgel Capsule 5's if you are pregnant or breastfeeding. Psortude-100 mg Softgel Capsule 5's increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Psortude-100 mg Softgel Capsule 5's

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches)

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not break or chew the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup provided by the pack. Shake the pack well before use.

Medicinal Benefits

Psortude-100 mg Softgel Capsule 5's belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Psortude-100 mg Softgel Capsule
  • Get plenty of fresh air.
  • Take regular sips of a cold drink.
  • Take ginger containing foods like ginger tea and ginger biscuits.
  • Do not take heavy meals at a time, take small and frequent meals.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Using a cold compress may help relieve itching and inflammation associated with conjunctivitis.
  • A warm compress and washing the eyes with water can help with crusting on the eyelids.
  • Avoid wearing contact lens until you feel better; use spectacles instead.
  • Do not rub the eyes.
  • Practise good hand hygiene and avoid touching the eyes to prevent the spread of infection.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Increase protein intake by eating protein-rich foods like eggs, fish, lean meat, beans, and nuts to support nail strength.
  • Include biotin-rich foods like salmon, avocado, bananas, almonds, and whole grains in your diet to promote nail health.
  • Boost iron intake by consuming iron-rich foods like spinach, red meat, lentils, and fortified cereals to prevent iron deficiency.
  • Moisturize your nails and cuticles regularly by applying cuticle oil or hand cream multiple times a day.
  • Keep your nails short to reduce the risk of breakage and snagging.
  • Avoid biting your nails, as it can cause significant damage to your nails and cuticles.
  • Consider taking biotin supplements after consulting your doctor, as they may help strengthen brittle nails.

Drug Warnings

Do not take Psortude-100 mg Softgel Capsule 5's if you are allergic to any of the components. Let your doctor know before using Psortude-100 mg Softgel Capsule 5's if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Psortude-100 mg Softgel Capsule 5's may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Psortude-100 mg Softgel Capsule 5's inform your doctor if you have any type of cancer. Do not take Psortude-100 mg Softgel Capsule 5's if you are pregnant or planning for pregnancy. Psortude-100 mg Softgel Capsule 5's should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Psortude-100 mg Softgel Capsule:
Combining Psortude-100 mg Softgel Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Psortude-100 mg Softgel Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Psortude-100 mg Softgel Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
How does the drug interact with Psortude-100 mg Softgel Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Psortude-100 mg Softgel Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Psortude-100 mg Softgel Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Psortude-100 mg Softgel Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Coadministration of pitavastatin with Psortude-100 mg Softgel Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Psortude-100 mg Softgel Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinVenetoclax
Severe
How does the drug interact with Psortude-100 mg Softgel Capsule:
Co-administration of venetoclax with Psortude-100 mg Softgel Capsule may significantly increase the blood levels and effects of venetoclax.

How to manage the interaction:
Although there is a possible interaction between venetoclax and Psortude-100 mg Softgel Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience any symptoms such as nausea, paleness, vomiting, diarrhea and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Taking cyclosporine and hydroxychloroquine can increases the blood levels of ciclosporine.

How to manage the interaction:
Co-administration of cyclosporine and hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Coadministration of deferasirox with Psortude-100 mg Softgel Capsule may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between deferasirox and Psortude-100 mg Softgel Capsule, they can be taken together if your doctor has prescribed them. However, contact your doctor immediately if experience nausea, vomiting, loss of hunger, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm. Do not stop using any medications without talking to a doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Coadministration of sulfasalazine with Psortude-100 mg Softgel Capsule may significantly increase the side effects on kidneys.

How to manage the interaction:
Although there is a possible interaction between sulfasalazine and Psortude-100 mg Softgel Capsule, they can be taken together if your doctor has prescribed them. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without first talking to a doctor.
How does the drug interact with Psortude-100 mg Softgel Capsule:
Taking tacrolimus with Psortude-100 mg Softgel Capsule may cause serious side effects on the kidneys.

How to manage the interaction:
Although taking tacrolimus and Psortude-100 mg Softgel Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, body aches, and severe pain in your upper stomach spreading to your back. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CYCLOSPORINE-100MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Psortude-100 mg Softgel Capsule can increase the effects of Psortude-100 mg Softgel Capsule. Avoid consuming grapefruit and grapefruit juice while taking Psortude-100 mg Softgel Capsule.

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Psortude-100 mg Softgel Capsule 5's Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Psortude-100 mg Softgel Capsule 5's acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.

If you miss a dose of Psortude-100 mg Softgel Capsule 5's, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Psortude-100 mg Softgel Capsule 5's. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Psortude-100 mg Softgel Capsule 5's may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Psortude-100 mg Softgel Capsule 5's is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and use sunscreen regularly.

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

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