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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Composition

AMBRISENTAN-5MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Pulmonext 5 Tablet 10's

Pulmonext 5 Tablet 10's belongs to the class of ‘anti-hypertensive drugs’, primarily used to treat high blood pressure in the arteries of lungs (pulmonary arterial hypertension). Hypertension is a medical condition, in which the blood exerts high pressure (force exerted by circulating blood) against the walls of blood vessels. This condition makes the heart to work harder in pumping the blood to the whole body. Pulmonary hypertension affects arteries in the lungs and the right side of the heart.

Pulmonext 5 Tablet 10's contains ‘Ambrisentan,’ which belongs to the class of ‘endothelin receptor blockers’. Ambrisentan works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. Pulmonext 5 Tablet 10's widens the constricted pulmonary arteries (blood vessels that carry blood from the heart to the lungs) and increases blood supply to the lungs, thus lowering the blood pressure.

In some cases, Pulmonext 5 Tablet 10's can cause side effects like headache, dizziness, palpitations, breathlessness, runny nose, feeling sick, diarrhoea, and fatigue. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Pulmonext 5 Tablet 10's or any other medicines, before starting Pulmonext 5 Tablet 10's. Inform your doctor if you have low blood pressure, lung, heart, kidney or liver problems, and anaemia (lack of blood cells). It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Do not stop taking Pulmonext 5 Tablet 10's without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. Do not consume alcohol with Pulmonext 5 Tablet 10's as it may increase the risk of low blood pressure. 

Uses of Pulmonext 5 Tablet 10's

Pulmonary arterial hypertension.

Directions for Use

Swallow Pulmonext 5 Tablet 10's as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Medicinal Benefits

Pulmonext 5 Tablet 10's is an anti-hypertensive medicine that treats high blood pressure in the arteries of lungs (pulmonary arterial hypertension (PAH)). It contains ‘Ambrisentan,’ an endothelin receptor blocker. Pulmonext 5 Tablet 10's works by inhibiting the action of Endothelin, a natural substance that constricts blood vessels and raises blood pressure. In people with PAH, the pulmonary arteries get narrower making the heart work harder to pump blood through them. Pulmonext 5 Tablet 10's widens these constricted arteries and makes it easier for the heart to pump blood, thus lowering the blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pulmonext 5 Tablet 10's

  • Headache
  • Dizziness
  • Swelling in your hands, legs, ankles, or feet
  • Palpitations
  • Breathlessness
  • Chest pain or discomfort
  • Stuffy nose, sinus pain
  • Flushing (redness of the skin)
  • Feeling sick
  • Diarrhoea
  • Feeling tired
  • Rash

Drug Warnings

Brief your medical history if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure) before starting Pulmonext 5 Tablet 10's. Pulmonext 5 Tablet 10's is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Pulmonext 5 Tablet 10's if you are a breastfeeding mother. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Do not drive or operate machinery since Pulmonext 5 Tablet 10's may cause side effects like dizziness and weakness, affecting your ability to concentrate and drive. Avoid consumption of alcohol with Pulmonext 5 Tablet 10's as it may increase the risk of low blood pressure. Pulmonext 5 Tablet 10's is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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AmbrisentanCiclosporin
Severe
AmbrisentanMipomersen
Severe

Drug-Drug Interactions

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AmbrisentanCiclosporin
Severe
How does the drug interact with Pulmonext 5 Tablet:
When Pulmonext 5 Tablet is taken with cyclosporine, this increases the blood levels of Pulmonext 5 Tablet. This can increase the risk of serious side effects such as liver problems, anemia, and fluid accumulation (particularly in the lungs).

How to manage the interaction:
Co-administration of ciclosporin with Pulmonext 5 Tablet can result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms such as fever with shivering, pain in your joints, swelling, bleeding or bruising easily, a rash or itchy skin, not feeling hungry, feeling tired, dark color urine, looking pale, dizziness, gaining weight suddenly, or breathing problem, consult a doctor. Do not stop using any medications without talking to a doctor.
AmbrisentanMipomersen
Severe
How does the drug interact with Pulmonext 5 Tablet:
Taking Pulmonext 5 Tablet with Mipomersen can increase the risk or severity of liver problems.

How to manage the interaction:
Taking Pulmonext 5 Tablet with Mipomersen together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AmbrisentanTizanidine
Severe
How does the drug interact with Pulmonext 5 Tablet:
Coadministration of Tizanidine with Pulmonext 5 Tablet may increase the risk or severity of developing low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Pulmonext 5 Tablet and Tizanidine, you can take these medicines together if your doctor advises. If you notice any symptoms like headache, dizziness, shortness of breath, chest pain, or sweating, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AmbrisentanLeflunomide
Severe
How does the drug interact with Pulmonext 5 Tablet:
Taking leflunomide and Pulmonext 5 Tablet can lead to or increase the risk or severity of developing liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and Pulmonext 5 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AmbrisentanTeriflunomide
Severe
How does the drug interact with Pulmonext 5 Tablet:
When Pulmonext 5 Tablet and Teriflunomide are taken together, the risk or severity of developing liver injury increases.

How to manage the interaction:
Although taking Pulmonext 5 Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmbrisentanLomitapide
Severe
How does the drug interact with Pulmonext 5 Tablet:
Taking Pulmonext 5 Tablet with Lomitapide can lead to or increase the risk or severity of developing liver problems.

How to manage the interaction:
Although there is a possible interaction, Pulmonext 5 Tablet can be taken with Lomitapide if prescribed by the doctor. Consult the prescriber if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Reduce sodium intake in your diet to maintain your blood pressure.
  • Eat natural and healthy foods by cutting down on high on sodium processed foods.
  • Lose those extra pounds, since being obese can be a risk factor for hypertension.
  • Exercise regularly to maintain good heart health.
  • Avoid smoking and alcohol intake.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • EPOPROSTENOL
  • SILDENAFIL
  • RIFAMPICIN
  • CYCLOSPORINE
  • ILOPROST

Special Advise

  • Keep a check on your daily blood pressure and if you notice any fluctuations, please consult a doctor.
  • You may be asked by your doctor to undergo blood and urine tests if you have been suffering from vomiting or dehydration.
  • If you have diabetes, using Pulmonext 5 Tablet 10's may affect your blood sugar levels. Inform your doctor so that your diabetes medication may be adjusted accordingly.
  • Your dietician may prescribe you a suitable exercise program and diet to manage your blood pressure.
  • Your doctor may also suggest liver function tests since Pulmonext 5 Tablet 10's may cause a change in liver enzymes.

Disease/Condition Glossary

Hypertension: It is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered as an essential risk factor for cardiovascular diseases and can be caused due to obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing. Blood pressure is measured in the ratio of systolic pressure to diastolic pressure. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure range lies in between 90/60 mmHg and 120/80 mmHg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.

Pulmonary Arterial Hypertension: It is referred to as high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs. Symptoms include shortness of breath, dizziness, and chest pressure.

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