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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

PYRIMETHAMINE-25MG

Manufacturer/Marketer :

Vikas Health Care

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pyrimethamine 25 mg Tablet

Pyrimethamine 25 mg Tablet is an antimalarial medicine used in the treatment of malaria. Malaria is a parasitic disease caused by the plasmodium species. The infection occurs when the mosquito bites and enters the human body. Symptoms may include chills, on-and-off fever, and sweating. This medicine is only used to treat the infection. It is not recommended to prevent or treat severe conditions (where the infection is spread to the brain, kidneys, or lungs). Pyrimethamine 25 mg Tablet is also used in the treatment of toxoplasmosis (infection caused by parasites toxoplasma gondii) and also in chemoprophylaxis of malaria.

Pyrimethamine 25 mg Tablet contains Pyrimethamine, which belongs to the class of antimalarial/antiparasitic drugs. It works by increasing the harmful, toxic and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading. In this way, Pyrimethamine 25 mg Tablet is used for the prevention of relapse of malaria caused by parasites.

Pyrimethamine 25 mg Tablet may cause certain side effects such as nausea, dizziness, vomiting, headache, diarrhoea, body pain, stomach discomfort, and injection site reactions. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor immediately. Pyrimethamine 25 mg Tablet should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on the severity of your disease. Always take the medicine on time without skipping any dose.

Pyrimethamine 25 mg Tablet should be avoided if you are allergic to it or any other artemisinin derivatives. It is contraindicated in patients with megaloblastic anemia. Inform your doctor if you have/had any conditions such as anemia,  liver/kidney disease, heart problem, or taking any other medicines before taking Pyrimethamine 25 mg Tablet as it may cause serious side effects under these conditions. If you are pregnant or breastfeeding, inform your doctor before taking Pyrimethamine 25 mg Tablet . This medicine is used in combination with other medicines for the treatment of malaria. 

Uses of Pyrimethamine 25 mg Tablet

Malaria, Toxoplasmosis

Directions for Use

Pyrimethamine 25 mg Tablet should be taken as advised by your doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not chew crush or break the medicine.

Medicinal Benefits

Pyrimethamine 25 mg Tablet contains Pyrimethamine, which belongs to the class of antimalarial/ antiparasitic drugs. It works by increasing the harmful, toxic and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading. In this way, Pyrimethamine 25 mg Tablet is used for the prevention of relapse of malaria caused by plasmodium species. Pyrimethamine 25 mg Tablet is in combination with other antimalarial medicines such as chloroquine or quinine for the treatment of malarial infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Pyrimethamine 25 mg Tablet
  • Eat foods rich in vitamins C and E, and healthy fats.
  • Consider soft foods like smoothies, soups, and scrambled eggs.
  • Take supplements like vitamins C and E, zinc, and omega-3 fatty acids under medical supervision.
  • Include anti-inflammatory foods like omega-3 rich foods, berries, leafy greens, and spices.
  • Avoid allergens and consider an elimination diet.
  • Practice gentle skin care with non-irritating cleansers and moisturizers.
  • Keep skin well-moisturized with fragrance-free products.
  • Monitor for complications like infection and temperature regulation.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Staying hydrated helps prevent hematuria by increasing urine production. You should drink about eight glasses of fluid per day, and more in hot weather.
  • Avoiding smoking as it is linked to urinary tract cancers.
  • Eat berries like Cranberries, blueberries, and raspberries can help promote urinary tract health and protect against infection.
  • Taking Vitamin C can help treat urinary tract infections.
  • Avoid irritants that can contribute to hematuria.
  • Empty the bladder regularly, as it can helps in preventing hematuria.

Drug Warnings

Avoid using Pyrimethamine 25 mg Tablet if you are allergic to it or any other artemisinin derivatives. Inform your doctor if you have/had any conditions such as liver/kidney disease, heart problem, or taking any other medicines before receiving Pyrimethamine 25 mg Tablet as it may cause serious side effects under these conditions. Pyrimethamine 25 mg Tablet is recommended for use in children only if prescribed by the paediatrician, and if administered, proper care and dosing should be checked. This medicine is used alone or in combination with other medicines for the treatment of malaria.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Try to add protein to your diet for malaria-induced weight loss.
  • Eating at the right time and taking proper rest is important for the patient to recover.
  • Avoid eating fried and processed foods, and junk oily and spicy foods can aggravate nausea and disturb the body's digestion process.
  • Eat nutritious food that helps to improve malaria-induced weakness
  • Keep your area and surroundings mosquito-free.
  • Use mosquito-repellent products to avoid the recurrence of infections and any other further complications.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Pyrimethamine 25 mg Tablet contains Pyrimethamine, which belongs to the class of antimalarial/ antiparasitic drugs. It works by increasing the harmful, toxic, and highly reactive free radicals in the blood. This kills the parasite and stops the infection from spreading.

No, do not stop taking Pyrimethamine 25 mg Tablet . It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve. Failure to do so might result in drug resistance, and treating any subsequent infection with the same medicine would be very difficult.

The common side-effects of Pyrimethamine 25 mg Tablet are nausea, vomiting, dizziness, diarrhoea, headache and injection site reactions. These side effects usually do not require any medical attention.

Disease/Condition Glossary

Malaria: It is a life-threatening parasitic disease caused by mosquito bites. When the mosquito bites, the plasmodium parasite enters the body multiplies in the liver, spreads via the bloodstream, and thus causes the infection by releasing toxic chemicals. Four types of plasmodium parasites can infect humans with malaria such as Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Symptoms may include chills, on-and-off fever, sweating, vomiting, etc.

Toxoplasmosis: It is an infection caused by parasites toxoplasma gondii found in contaminated food and cat faeces. It can cause serious complications for pregnant women, such as miscarriage, stillbirths, and damage to the baby’s brain and other organs, particularly the eyes, at birth or early childhood, and people with weakened immune systems. Symptoms include muscle pain, fever, headache, etc.

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