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  3. Qdine 200mg Tablet

Qdine 200mg Tablet, Pack of 1 Tablet
Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

CHLOROQUINE-200MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Qdine 200mg Tablet

Qdine 200mg Tablet belongs to the class of medications called 'quinoline' primarily used to treat malaria. Qdine 200mg Tablet gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. Qdine 200mg Tablet is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis). 

Qdine 200mg Tablet contains 'chloroquine' which acts by killing the malarial parasites, i.e. Plasmodium and stops the formation of the nontoxic heme metabolite hemozoin by the parasite. Heme part of the red blood cells is broken by the malarial, causing parasites. Qdine 200mg Tablet prevents the breakdown of heme part and is actually toxic to the parasite. It kills the parasitic form living in red blood cells that resides in the liver.

Qdine 200mg Tablet should be taken as prescribed by your doctor. The dose of Qdine 200mg Tablet can vary depending upon your condition and the severity of the infection. The common side effects of Qdine 200mg Tablet include vomiting, nausea, hair loss and itchy skin. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.

Before starting Qdine 200mg Tablet, please inform your doctor if you are allergic to chloroquine or have kidney or liver problems. Do not take Qdine 200mg Tablet on your own. Qdine 200mg Tablet is safe to use during pregnancy and breastfeeding. Prolonged use of Qdine 200mg Tablet may have a severe risk on the heart and retina of the eyes leading to pounding heartbeats and permanent vision problems. 

Uses of Qdine 200mg Tablet

Malaria, Intestinal amoebiasis, Rheumatoid arthritis

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Qdine 200mg Tablet falls into a group of medicines known as antimalarials, indicated for treating or preventing malaria. Qdine 200mg Tablet contains chloroquine, which belongs to quinoline. It works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism. Qdine 200mg Tablet is also indicated for the treatment of rheumatoid arthritis and autoimmune diseases like lupus and intestinal infection caused by amoeba (amoebiasis).

Storage

Store in a cool and dry place away from sunlight
Side effects of Qdine 200mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Drug Warnings

Qdine 200mg Tablet does not respond well against all malaria strains, so consult with your doctor if you do not respond well to Qdine 200mg Tablet. This medicine can affect heart health, especially if a person is taking medications, including the antibiotic azithromycin and anticancer like tamoxifen. An individual must consult with the doctor if they are noticing fast or pounding heartbeats and sudden dizziness. This medicine cannot be used for a long duration as it may cause irreversible damage to the eye that could lead to vision problems. Qdine 200mg Tablet cannot be used in persons who have heart disease, heart rhythm disorder, diabetes, a stomach disorder, an allergy to quinine, liver or kidney disease, psoriasis, alcoholism, porphyria (a genetic enzyme disorder that affects the skin or nervous system), a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Consult with your doctor if you are pregnant or breastfeeding as this medicine could only be used if prescribed by the doctor. 

Drug-Drug Interactions

verifiedApollotooltip
ChloroquineMesoridazine
Critical
ChloroquineTelavancin
Critical

Drug-Drug Interactions

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ChloroquineMesoridazine
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking Qdine 200mg Tablet with Mesoridazine together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Mesoridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineTelavancin
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet together with telavancin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Telavancin with Qdine 200mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase alfa
Critical
How does the drug interact with Qdine 200mg Tablet:
When Agalsidase alfa is used with Qdine 200mg Tablet, it may decrease the effectiveness of the Agalsidase alfa.

How to manage the interaction:
Taking Agalsidase alfa with Qdine 200mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineSaquinavir
Critical
How does the drug interact with Qdine 200mg Tablet:
Using saquinavir together with Qdine 200mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Qdine 200mg Tablet with Saquinavir is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquinePazopanib
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking pazopanib with Qdine 200mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pazopanib with Qdine 200mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ChloroquineLevacetylmethadol
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Levacetylmethadol together with Qdine 200mg Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Levacetylmethadol is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ChloroquineBepridil
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet together with bepridil can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Bepridil is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately.
ChloroquineAuranofin
Critical
How does the drug interact with Qdine 200mg Tablet:
Taking Auranofin with Qdine 200mg Tablet can increase the risk of blood disorders and other severe side effects

How to manage the interaction:
Taking Auranofin with Qdine 200mg Tablet is not recommended, as it may lead to an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
ChloroquineAgalsidase beta
Critical
How does the drug interact with Qdine 200mg Tablet:
Using Qdine 200mg Tablet with Agalsidase beta can reduce the effectiveness of agalsidase beta.

How to manage the interaction:
Taking Agalsidase beta with Qdine 200mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ChloroquineThioridazine
Critical
How does the drug interact with Qdine 200mg Tablet:
When Thioridazine and Qdine 200mg Tablet are taken together, can increase the chance of a serious abnormal heart rhythm

How to manage the interaction:
Taking Qdine 200mg Tablet with Thioridazine is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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CHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grape fruit products while using Qdine 200mg Tablet, can increase the risk of irregular heartbeat, which may result in side effects such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Avoid grape fruit and its products while taking Qdine 200mg Tablet.

Diet & Lifestyle Advise

  • Always take Qdine 200mg Tablet with meals for reduced gastric irritation.
  • Adequate nutrition is the key for improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Qdine 200mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:51 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
CHLOROQUINE-200MGDisorders of porphyrin and bilirubin metabolism
Severe
CHLOROQUINE-200MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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CHLOROQUINE-200MGDisorders of porphyrin and bilirubin metabolism
Severe
How does the disease interact with Qdine 200mg Tablet:
Porphyria: In porphyria the use of Qdine 200mg Tablet may aggravate this condition. Avoid Qdine 200mg Tablet use until it is required.

How to manage the interaction:
If the risks aren't expected to outweigh the possible advantages, Qdine 200mg Tablet shouldn't be utilized on these patients.
CHLOROQUINE-200MGOther cardiac arrhythmias
Moderate
How does the disease interact with Qdine 200mg Tablet:
Arrhythmias:Qdine 200mg Tablet has adverse effect like prolongation of QT interval, ventricular arrhythmias and torsades de pointes. Monitor ECG before initiation and during the therapy.

How to manage the interaction:
If you have sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat while taking these medications, whether they are taken together or separately, you should seek immediate assistance from a doctor. A close monitoring of ECG is required.
CHLOROQUINE-200MGEpilepsy
Moderate
How does the disease interact with Qdine 200mg Tablet:
Seizures: Qdine 200mg Tablet may cause epileptic seizures in susceptible patients. Administer Qdine 200mg Tablet in patients with history of epilepsy.

How to manage the interaction:
In those who are vulnerable, Qdine 200mg Tablet may result in epileptic fits. Patients who already have epileptic fits or have a low tolerance for seizures may be at greater risk.
CHLOROQUINE-200MGOther diseases of blood and blood-forming organs
Moderate
How does the disease interact with Qdine 200mg Tablet:
Bone marrow suppression: With the use of Qdine 200mg Tablet adverse effects such as neutropenia, agranulocytosis, aplastic anemia, and thrombocytopenia. In patients with preexisting bone marrow suppression use cautiously and monitor for complete blood count. Discontinue the Qdine 200mg Tablet if any serious blood disorder is suspected.

How to manage the interaction:
It is important to inform your doctor if you have prior conditions like bone marrow suppression, a complete blood picture is advised to be taken if you are on a long term therapy with Qdine 200mg Tablet. If you suspect any blood disorders, please inform it to your doctor immediately.
CHLOROQUINE-200MGOther hearing loss
Moderate
How does the disease interact with Qdine 200mg Tablet:
Ototoxicity: Rarely, Qdine 200mg Tablet was been associated with ototoxicity.The use of Qdine 200mg Tablet has been associated rarely with ototoxicity. With long-term, high-dose Qdine 200mg Tablet therapy which is irreversible nerve-type deafness may occur. In some patients with preexisting auditory damage, tinnitus, decrease in hearing may occur. Use with caution and discontinue therapy if new auditory defects occur or if hearing loss becomes worse.

How to manage the interaction:
If you any existing hearing damage, do not forget to inform it your doctor, so that a close monitoring can be done during the treatment with Qdine 200mg Tablet.
CHLOROQUINE-200MGPsoriasis
Moderate
How does the disease interact with Qdine 200mg Tablet:
In psoriasis patients, the Qdine 200mg Tablet use may exacerbate severe attack of psoriasis. Do not use Qdine 200mg Tablet unless the potential benefits vs risks outweighs.

How to manage the interaction:
It is important to tell your doctor if you have any existing skin conditions like psoriasis. Your doctor may prescribe the medication, if the benefits are more than the risks.
CHLOROQUINE-200MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Qdine 200mg Tablet:
myasthenia gravis Use of Qdine 200mg Tablet may exacerbate new onset of symptoms in patients with previously diagnosed myasthenia gravis. Use cautiously.

How to manage the interaction:
If you are suffering from myasthenia gravis, do not forget to tell it to your doctor. If you are taking Qdine 200mg Tablet and experiencing symptoms like muscle weakness or weakness of the arms and legs, drooping of upper eyelid, difficulty speaking, difficulty swallowing, double vision, tiredness, or shortness of breath please inform your doctor.

FAQs

Qdine 200mg Tablet works by preventing the formation of the nontoxic heme metabolite hemozoin by the parasite. Due to this, the parasite dies from its own toxic by-products released due to haemoglobin's metabolism.

The use of Qdine 200mg Tablet is not allowed in persons who are already taking any antibiotic (azithromycin) as it may cause dangerous effects on the heart.

No such effect has been reported yet. Always consult your doctor for the change of dose regimen or an alternative medicine if needed.

No such harmful interaction has been reported in patients who take this drug under strict doctors' surveillance. However, some patients might experience eye (retina) damage and cause pounding heart, so patient taking Qdine 200mg Tablet is advised to consult a doctor and have regular check-ups cyclically.

There may be a risk of hemolysis in patients with G6PD deficiency while using Qdine 200mg Tablet. Doctor's consultation is mandatory before you start this medication.

Drug-Drug Interactions Checker List

  • PHENYLBUTAZONE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • AMPICILLIN
  • CIMETIDINE
  • TAMOXIFEN

Special Advise

Do not take Qdine 200mg Tablet if you have had a previous reaction to Qdine 200mg Tablet, or if you have certain eye problems involving your retina. Tell your healthcare provider about any problems you may have with your eyes.

Disease/Condition Glossary

Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing, and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point, and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure, and jaundice due to excessive red blood cell death due to plasmodium growth inside them.

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