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  3. R-Trax 10 Tablet 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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Composition :

METHOTREXATE-10MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About R-Trax 10 Tablet

R-Trax 10 Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis, severe psoriasis, and severe psoriatic arthritis. R-Trax 10 Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).

R-Trax 10 Tablet contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, R-Trax 10 Tablet prevents and stops the growth of cancer cells, thereby helps treat cancer. R-Trax 10 Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.

In some cases, R-Trax 10 Tablet may cause common side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience these side effects persistently.

Take R-Trax 10 Tablet exactly as prescribed by the doctor; daily intake of R-Trax 10 Tablet could lead to serious toxic effects. Do not take R-Trax 10 Tablet if you are pregnant or breastfeeding. R-Trax 10 Tablet may cause dizziness and fatigue, so drive only if you are alert. Avoid consuming alcohol whilst on treatment with R-Trax 10 Tablet . Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your medications and health condition to rule out any unpleasant side effects/interactions.

Uses of R-Trax 10 Tablet

Rheumatoid arthritis, Psoriatic arthritis, Psoriasis, Cancer

Directions for Use

R-Trax 10 Tablet should be taken exactly as prescribed by the doctor. Tablet/capsule: Take it one hour after food in the evening or as advised by the doctor. Swallow the tablet/capsule as a whole with a glass of water whilst standing or sitting upright; do not break or chew it. Oral solution: Take the prescribed quantity by mouth using the dosing syringe.

Medicinal Benefits

R-Trax 10 Tablet belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis (arthritis in children), severe psoriasis, and severe psoriatic arthritis. R-Trax 10 Tablet helps treat rheumatoid arthritis and psoriatic arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. R-Trax 10 Tablet treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. R-Trax 10 Tablet is used alone or in combination with other medicines to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). R-Trax 10 Tablet prevents and stops the growth of cancer cells by interfering with DNA production. R-Trax 10 Tablet may also be used to treat inflammatory bowel disease.

Storage

Keep R-Trax 10 Tablet out of reach and sight of children.
Side effects of R-Trax 10 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.

Drug Warnings

Do not take R-Trax 10 Tablet if you are allergic to any of its contents; if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, chronic liver disease; if you are pregnant or breastfeeding. Talk to your doctor before taking R-Trax 10 Tablet if you have/had liver or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if you are due to have any vaccinations, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. R-Trax 10 Tablet may cause dizziness and fatigue, so drive only if you are alert. Take R-Trax 10 Tablet exactly as directed by the doctor as it may cause serious problems if not taken in the dose and duration prescribed by the doctor. Stop taking R-Trax 10 Tablet and consult your doctor immediately if you have mouth sores, diarrhoea, a fever, dehydration, cough, bleeding, shortness of breath, any signs of infection, or a skin rash.

Drug-Drug Interactions

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MethotrexateEtretinate
Critical

Drug-Drug Interactions

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MethotrexateEtretinate
Critical
How does the drug interact with R-Trax 10 Tablet:
Co-administration of Etretinate with R-Trax 10 Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Taking Etretinate with R-Trax 10 Tablet is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with R-Trax 10 Tablet:
Coadministration of R-Trax 10 Tablet with ibuprofen can increase the effect and side effects of R-Trax 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between R-Trax 10 Tablet and ibuprofen, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, pallor, dizziness or fainting, unusual bruising or bleeding, seizures, infection; as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with R-Trax 10 Tablet:
Coadministration of Everolimus with R-Trax 10 Tablet can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Everolimus with R-Trax 10 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with R-Trax 10 Tablet:
Co-administration of R-Trax 10 Tablet and esomeprazole can increase the blood levels and side effects of R-Trax 10 Tablet.

How to manage the interaction:
Although taking Esomeprazole with R-Trax 10 Tablet can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Trax 10 Tablet:
Coadministration of leflunomide with R-Trax 10 Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and R-Trax 10 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with R-Trax 10 Tablet:
Coadministration of Tenofovir disoproxil with R-Trax 10 Tablet may increase the levels and side effects of Tenofovir disoproxil.

How to manage the interaction:
Although there is a possible interaction between tenofovir disoproxil and R-Trax 10 Tablet, you can take these medicines when prescribed by your doctor. However, if you experience any symptoms such as vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, breathing difficulty, or dizziness, consult your doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with R-Trax 10 Tablet:
Combine use of hydroxychloroquine with R-Trax 10 Tablet may increase the effectiveness of everolimus.

How to manage the interaction:
Although there is a possible interaction between hydroxychloroquine and R-Trax 10 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, dizziness. Consult your doctor. Do not stop using any medications without first consulting to your doctor.
How does the drug interact with R-Trax 10 Tablet:
Co-administration of R-Trax 10 Tablet with Indomethacin can increase the levels and side effects of R-Trax 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between R-Trax 10 Tablet and Indomethacin, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms like mouth sores or ulcers, nausea, vomiting, diarrhea, rash, appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, breathing difficulty, a dry cough, dizziness or fainting, unusual bruising or bleeding, seizures(fits), infection, as well as flu-like signs (fever, chills, body pains, sore throat, and weakening of the muscles), consult a doctor immediately. Do not stop using medications without a doctor's advice.
How does the drug interact with R-Trax 10 Tablet:
Co-administration of R-Trax 10 Tablet with pantoprazole can increase the levels and side effects of R-Trax 10 Tablet.

How to manage the interaction:
Although there is a possible interaction between pantoprazole and R-Trax 10 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with R-Trax 10 Tablet:
Taking deferasirox with R-Trax 10 Tablet may increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between deferasirox and R-Trax 10 Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate

Drug-Food Interactions

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METHOTREXATE-10MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Caffeine may reduce the effectiveness of R-Trax 10 Tablet. Avoid taking caffeine while taking R-Trax 10 Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

Arthritis:

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Psoriasis:

  • Include foods such as cherries, berries, leafy vegetables, salmon, sardines, and fish rich in omega-3 fatty acids.
  • Consume antioxidant-rich spices and herbs like cumin, ginger, sage and thyme.
  • Avoid processed foods, refined sugars, and fatty foods.
  • Limit intake of food that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a good sleep cycle would be helpful.
  • Avoiding getting in contact with harsh soaps, detergents and rough fabrics.

Cancer:

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Side Effects of R-Trax 10 Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Unusual fatigue
  • Dizziness
  • Headache
  • Loss of appetite
  • Elevated liver enzymes
  • Lowered resistance to infections
  • Tingling sensation
  • Leukopenia (decreased number of white blood cells)
  • Soreness of mouth and lips

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

R-Trax 10 Tablet acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.

R-Trax 10 Tablet works by suppressing the overactive immune system that is responsible for causing psoriasis. R-Trax 10 Tablet interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis and psoriatic arthritis.

Diarrhoea might be a side-effect of R-Trax 10 Tablet . Stop taking R-Trax 10 Tablet and consult your doctor if you have diarrhoea. Do not take anti-diarrheal medicine on your own.

R-Trax 10 Tablet can affect egg and sperm production and could lead to birth defects. Women of child-bearing potential and men using R-Trax 10 Tablet must use effective contraception while on treatment with R-Trax 10 Tablet and for at least six months after stopping the treatment. R-Trax 10 Tablet can lead to infertility. Therefore male patients are advised to talk with their doctor regarding the possibility of sperm preservation before starting the treatment with R-Trax 10 Tablet .

R-Trax 10 Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

R-Trax 10 Tablet may cause mouth sores. Stop taking R-Trax 10 Tablet and consult your doctor if you have sores in the mouth. Your doctor may recommend folate supplements to treat mouth sores.

Drug-Drug Interactions Checker List

  • CELECOXIB
  • ACETAMINOPHEN
  • HYDROCODONE
  • DULOXETINE
  • ETANERCEPT
  • ADALIMUMAB
  • ESOMEPRAZOLE
  • HYDROXYCHLOROQUINE

Special Advise

  • Women of child-bearing age must use effective contraception whilst on treatment with R-Trax 10 Tablet and for at least 6 months after the last dose.
  • Male patients are advised to consult their doctor regarding the possibility of sperm preservation before starting the treatment as R-Trax 10 Tablet may cause infertility.
  • R-Trax 10 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
  • Your doctor may advise regular blood tests, kidney and liver tests to monitor your condition.
  • If you miss a dose of R-Trax 10 Tablet , call your doctor and ask if you should take the missed dose or not.

Disease/Condition Glossary

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriatic arthritis: It is a type of inflammatory arthritis which occurs in patients with psoriasis. It could also occur in patients without psoriasis, particularly in those who have relatives with psoriasis. It affects large joints in the lower extremities, distal joints of toes and fingers, back, and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin, and pain.

Psoriasis: It is a chronic autoimmune skin condition that causes the skin to multiply ten times faster than normal. This leads to a rapid build-up of skin cells, causing scaling on the skin surface. Symptoms include inflamed, red, raised patches of skin, soreness around the patches, itching, burning sensations, painful, swollen joints, and dry skin.

Cancer: It is a genetic change in which the cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer, namely benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy. 

Have a query?

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking R-Trax 10 Tablet .

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Pregnancy

Unsafe

R-Trax 10 Tablet may cause serious birth defects. It is not recommended to take R-Trax 10 Tablet while you are pregnant.

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Breast Feeding

Unsafe

R-Trax 10 Tablet passes into breast milk. Avoid breastfeeding whilst on treatment with R-Trax 10 Tablet .

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Driving

Caution

R-Trax 10 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you experience these symptoms.

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Liver

Caution

Do not take R-Trax 10 Tablet if you have chronic liver disease. Please consult your doctor if you have liver impairment before taking R-Trax 10 Tablet .

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking R-Trax 10 Tablet .

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Children

Caution

R-Trax 10 Tablet should be used with caution in children and only if prescribed by the doctor.

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