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Reviewed By Hari Kumar , MBBS
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Composition :

ABEMACICLIB-150MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ramiven 150 mg Tablet

Ramiven 150 mg Tablet belongs to the group of anti-cancer drugs called kinase inhibitors used alone or in combination with other anti-cancer drugs to treat certain types of breast cancer. Breast cancer is a type of cancer that develops in the breast when the breast cells begin to grow abnormally.

Ramiven 150 mg Tablet contains Abemaciclib which works by blocking cyclin-dependent kinase 4 and 6 proteins, which are necessary for the growth and division of the cells. Thereby, slows down the growth of cancer cells and delays the progression of cancer.

Take Ramiven 150 mg Tablet in the dose and duration prescribed by your doctor. Ramiven 150 mg Tablet may cause certain common side effects such as nausea, diarrhoea, abdominal pain, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

Avoid taking Ramiven 150 mg Tablet if you are pregnant or breastfeeding. Ramiven 150 mg Tablet may cause dizziness, so drive only if you are alert. Ramiven 150 mg Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Ramiven 150 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Ramiven 150 mg Tablet to rule out any side effects.

Uses of Ramiven 150 mg Tablet

Breast Cancer

Directions for Use

Swallow Ramiven 150 mg Tablet as a whole with water. Do not crush, chew or break it.

Medicinal Benefits

Ramiven 150 mg Tablet is an anti-cancer drug used in the treatment of certain types of breast cancers. Ramiven 150 mg Tablet is used either independently or in conjunction with other chemotherapy medications. Ramiven 150 mg Tablet works by inhibiting cyclin-dependent kinase 4 and 6 (CDK) which are responsible for the uncontrolled growth and proliferation of cancer cells. By inhibiting these, Ramiven 150 mg Tablet helps prevent the progression of the disease, nips the spread and shrinks the tumour tissue.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ramiven 150 mg Tablet
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Your doctor will perform a physical examination and review your medical history to identify possible causes of lymphocytosis, ranging from infections to autoimmune disorders or even blood cancers.
  • Monitor your lymphocytes with regular blood tests.
  • Regular exercise, such as walking or yoga, helps strengthen the immune system.
  • Try to get enough sleep that will be enhancing the immune system for your body's recovery.
  • Give up smoking and drink within limit to keep your immune system and health in good condition.
  • Consult a hematologist or doctor to identify the cause of thrombocytopenia (decreased platelet count) and plan treatment.
  • Foods rich in vitamins B12, C, folate, and iron may help boost platelet count.
  • Avoid heavy lifting, bending, or straining to reduce bleeding risk.
  • Stay hydrated by drinking plenty of water to help prevent bleeding.
  • Avoid alcohol and tobacco to prevent lowering platelet count and reduce bleeding risk.
  • Regular blood tests help monitor platelet count and detect any changes.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.

Drug Warnings

Do not take Ramiven 150 mg Tablet if you are allergic to any of its contents. Talk to your doctor before taking Ramiven 150 mg Tablet if you have liver problems, heart/heart rhythm disorders, blood clot issues, or kidney problems. Avoid taking Ramiven 150 mg Tablet if you are pregnant or breastfeeding. Ramiven 150 mg Tablet may cause dizziness, so drive only if you are alert. Ramiven 150 mg Tablet should not be given to children as safety has not been established. Avoid consuming alcohol along with Ramiven 150 mg Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Ramiven 150 mg Tablet to rule out any side effects.

Drug-Drug Interactions

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AbemaciclibCobicistat
Severe

Drug-Drug Interactions

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How does the drug interact with Ramiven 150 mg Tablet:
Coadministration of Ramiven 150 mg Tablet with Atazanavir can reduce the metabolism and increase the levels of Ramiven 150 mg Tablet in the body. This increases the risk or severity of side effects like liver problems or impaired bone marrow function resulting in the risk of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Atazanavir together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbemaciclibCobicistat
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Cobicistat can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Cobicistat together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ramiven 150 mg Tablet:
Using Ramiven 150 mg Tablet together with ketoconazole can significantly increase the blood levels of Ramiven 150 mg Tablet.

How to manage the interaction:
Taking Ketoconazole and Ramiven 150 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, abdominal pain, decreased appetite, mouth sores, blood clots, hair loss, liver problems, and impaired bone marrow function resulting in low numbers of different types of blood cells, consult a doctor. Do not discontinue any medication without consulting a doctor.
AbemaciclibBoceprevir
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Boceprevir can increase the levels of Ramiven 150 mg Tablet in the body. This increases the risk or severity of liver problems or impaired bone marrow which can increase the risk of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Boceprevir together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in the phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AbemaciclibSaquinavir
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Saquinavir can lead to or increase the risk or severity of developing liver injury or serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Saquinavir together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, abdominal pain, decreased appetite, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Voriconazole can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Voriconazole together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, shortness of breath, abdominal pain, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbemaciclibLomitapide
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Lomitapide can lead to or increase the risk or severity of developing liver damage.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Lomitapide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbemaciclibDelavirdine
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Delavirdine can lead to or increase the risk or severity of developing liver damage or serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Delavirdine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Etanercept can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Etanercept together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbemaciclibVoclosporin
Severe
How does the drug interact with Ramiven 150 mg Tablet:
Taking Ramiven 150 mg Tablet with Voclosporin can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Ramiven 150 mg Tablet with Voclosporin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ABEMACICLIB-150MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ABEMACICLIB-150MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit or Grapefruit juice with Ramiven 150 mg Tablet dose can increase the blood levels of Ramiven 150 mg Tablet. You should avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ramiven 150 mg Tablet. Contact a doctor immediately if you experience symptoms of nausea, vomiting, diarrhea, abdominal pain, decreased appetite, or mouth sores.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ramiven 150 mg Tablet works by inhibiting CDK 4 and 6, which are proteins that cause uncontrolled growth of cancer cells.

Ramiven 150 mg Tablet might cause fertility problems in males and may affect your ability to father a child. Talk to your doctor if you have any concerns regarding this.

Do not stop taking Ramiven 150 mg Tablet on your own. You are advised to take Ramiven 150 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Ramiven 150 mg Tablet.

Diarrhoea is a common side effect of Ramiven 150 mg Tablet which sometimes might be severe. Consult your doctor if you experience diarrhoea while on treatment with Ramiven 150 mg Tablet, your doctor might reduce the dose or ask you to stop taking Ramiven 150 mg Tablet temporarily.

Ramiven 150 mg Tablet might cause neutropenia (low blood cell count). Regular monitoring of white blood cell count before and during treatment with Ramiven 150 mg Tablet is advised.

Avoid taking ketoconazole (anti-fungal medication) while on treatment with Ramiven 150 mg Tablet. Also, avoid grapefruit, and its juice while on treatment with Ramiven 150 mg Tablet as it might increase the amount of Ramiven 150 mg Tablet in blood.

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • LOPINAVIR
  • RITONAVIR
  • DABIGATRAN ETEXILATE
  • DIGITOXIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • ST JOHN'S WORT

Special Advise

  • Women of child-bearing age should use effective contraception during treatment with Ramiven 150 mg Tablet and for 3weeks after the last dose of Ramiven 150 mg Tablet.
  • Avoid breastfeeding during treatment with Ramiven 150 mg Tablet and for 3weeks after the last dose of Ramiven 150 mg Tablet.
  • Regular monitoring of white blood cell count and liver function before and during treatment with Ramiven 150 mg Tablet is advised.
  • Ramiven 150 mg Tablet may cause serious blood clots. Inform your doctor immediately if you experience symptoms of blood clots such as pain, swelling in the arms or legs, rapid breathing, rapid heart rate, chest pain, and shortness of breath.
  • Avoid taking ketoconazole (anti-fungal medication) while on treatment with Ramiven 150 mg Tablet. 

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in the breast when the breast cells begin to grow abnormally. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.

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