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  3. Rasilez 300 mg Tablet 7's

Rasilez 300 mg Tablet 7's, Pack of 7 TabletS
Rasilez 300 mg Tablet 7's, Pack of 7 TabletS
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

ALISKIREN-300MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rasilez 300 mg Tablet

Rasilez 300 mg Tablet belongs to the class of drugs called direct renin inhibitors used in the treatment of essential hypertension. Essential hypertension is high blood pressure without a known secondary cause. 

Rasilez 300 mg Tablet contains Aliskiren which works by inhibiting the action of renin, an enzyme that helps the body to make angiotensin I, which is converted to angiotensin II (tightens and narrows blood vessels which increases the blood pressure). Thus, it reduces the production of angiotensin I and II. This helps to relax and widen the blood vessels and lower blood pressure. 

Take Rasilez 300 mg Tablet as prescribed. Your doctor will advise how often you take Rasilez 300 mg Tablet based on your medical condition. Sometimes, Rasilez 300 mg Tablet may cause common side effects such as dizziness, headache, back pain, diarrhoea, high levels of potassium in the blood or tiredness. Most of these side effects of Rasilez 300 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Aliskiren or any other ingredients of Rasilez 300 mg Tablet or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, and may cause difficulty breathing) to an ACE inhibitor medicine, inform your doctor. Rasilez 300 mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause injury and death to the developing fetus. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Rasilez 300 mg Tablet. Rasilez 300 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established. 

Uses of Rasilez 300 mg Tablet

Essential hypertension (high blood pressure)

Directions for Use

Take Rasilez 300 mg Tablet as advised by your doctor. Swallow it as a whole with a glass of water daily at the same time for effective results. Do not crush, chew or break it.

Medicinal Benefits

Rasilez 300 mg Tablet contains Aliskiren used in the treatment of essential hypertension (high blood pressure). It inhibits the action of renin, an enzyme that helps the body to produce angiotensin II (tightens and narrows blood vessels which increases blood pressure). Thus, it reduces the production of angiotensin II. This helps to relax and widen the blood vessels and lower blood pressure. Thereby, it helps to reduce the risk of heart failure, stroke, heart attack or kidney failure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Rasilez 300 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.

Drug Warnings

If you are allergic to Aliskiren or any other ingredients of Rasilez 300 mg Tablet or if you have ever had a reaction called angioedema (swelling of the face, lips, tongue, throat, arms, and legs, and may cause difficulty breathing) to an ACE inhibitor medicine, inform your doctor. Rasilez 300 mg Tablet is not recommended for pregnant women, especially in the second and third trimesters, as it may cause injury and death to the developing fetus. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking Rasilez 300 mg Tablet. Rasilez 300 mg Tablet is not recommended for children below 18 years as the safety and effectiveness were not established. Do not consume alcohol with Rasilez 300 mg Tablet as it may worsen dizziness. Avoid potassium supplements with Rasilez 300 mg Tablet as they may lead to high potassium levels in the blood. If you have severe and persistent diarrhoea, you are recommended to stop taking Rasilez 300 mg Tablet.

Drug-Drug Interactions

verifiedApollotooltip
AliskirenAzilsartan medoxomil
Critical
AliskirenEnalapril
Critical

Drug-Drug Interactions

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AliskirenAzilsartan medoxomil
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Taking Rasilez 300 mg Tablet with Azilsartan medoxomil can increase the risk of low blood pressure and high potassium levels in the body.

How to manage the interaction:
Taking Azilsartan medoxomil with Rasilez 300 mg Tablet is generally avoided as it may lead to an interaction, it can be taken if prescribed by the doctor. Consult the doctor if you experience vomiting, weakness, tingling in your hands and feet, or palpitations. Make sure to hydrate while taking these medications. It is advised to reduce the intake of potassium-rich foods. Do not discontinue any medications without a doctor's advice.
AliskirenEnalapril
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Using Rasilez 300 mg Tablet together with enalapril may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood.

How to manage the interaction:
Taking enalapril with Rasilez 300 mg Tablet is not recommended, but it can be taken together if your doctor advises. However, contact your doctor if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, or feelings of heaviness in the legs. Do not stop taking any medications without consulting a doctor.
AliskirenRamipril
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Taking Rasilez 300 mg Tablet together with ramipril may increase the risk of serious side effects such as kidney problems, low blood pressure, and high potassium levels in the blood. High levels of potassium can develop into a condition known as hyperkalemia, which in severe cases can lead to kidney problems, muscle paralysis and irregular heart rhythm.

How to manage the interaction:
Taking Ramipril with Rasilez 300 mg Tablet is not recommended, but can be taken if prescribed by a doctor. However, consult your doctor if you feel nausea, vomiting, weakness, confusion, tingling in the hands and feet, a sensation of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. You must drink enough fluids while taking these medications. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes. Do not discontinue any medications without a doctor's advice.
AliskirenPerindopril
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Combining Rasilez 300 mg Tablet with Perindopril can increase the risk of low blood pressure, high potassium levels, and kidney damage.

How to manage the interaction:
Taking Perindopril with Rasilez 300 mg Tablet is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AliskirenOlmesartan medoxomil
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Using Rasilez 300 mg Tablet together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Olmesartan medoxomil with Rasilez 300 mg Tablet is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AliskirenLisinopril
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Combining Rasilez 300 mg Tablet with Lisinopril can increase the potassium levels in the blood.

How to manage the interaction:
Although taking Rasilez 300 mg Tablet and lisinopril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience symptoms including weakness, tiredness, confusion, numbness or tingling, and irregular heartbeats. Do not discontinue any medications without a doctor's advice.
AliskirenTelmisartan
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Co-administration of Rasilez 300 mg Tablet with Telmisartan can increase the risk of hyperkalemia (high potassium levels in the blood).

How to manage the interaction:
Taking Telmisartan with Rasilez 300 mg Tablet can possibly lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
AliskirenValsartan
Critical
How does the drug interact with Rasilez 300 mg Tablet:
Using Rasilez 300 mg Tablet together with Valsartan may increase the risk of serious side effects (kidney problems, low blood pressure, or high potassium levels).

How to manage the interaction:
Taking Valsartan with Rasilez 300 mg Tablet is not advised as it can result in an interaction, it can be taken if a doctor has advised it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
AliskirenDapagliflozin
Severe
How does the drug interact with Rasilez 300 mg Tablet:
Co-administration of Dapagliflozin with Rasilez 300 mg Tablet may increase the risk of dehydration and low blood pressure.

How to manage the interaction:
If you are supposed to use Dapagliflozin and Rasilez 300 mg Tablet together, a doctor may adjust the dose and monitor you more frequently. However, if you experience dizziness, fainting, headache, lightheadedness, and/or changes in pulse or heart rate, contact a doctor. Do not discontinue the medication without consulting a doctor.
AliskirenCiclosporin
Severe
How does the drug interact with Rasilez 300 mg Tablet:
The combined use of Rasilez 300 mg Tablet and ciclosporin can significantly increase the blood levels and effects of Rasilez 300 mg Tablet, which may lead to low blood pressure, hyperkalemia (high potassium levels) in the body. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythms. If you are elderly, dehydrated, or have kidney disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Taking Rasilez 300 mg Tablet and ciclosporin will lead to an interaction, they can be taken together if your doctor has prescribed them. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. It is advised to reduce intake of potassium-rich foods such as tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and potassium-containing salt substitutes.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
  • Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:16 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rasilez 300 mg Tablet contains Aliskiren which works by inhibiting the action of renin, an enzyme that helps the body to produce angiotensin II (tightens and narrows blood vessels which increases blood pressure). Thus, it reduces the production of angiotensin II. This helps to relax and widen the blood vessels and lower blood pressure.

You are not recommended to take potassium supplements with Rasilez 300 mg Tablet as it may increase the levels of potassium in the blood (hyperkalaemia). However, please consult a doctor before taking other medicines or supplements with Rasilez 300 mg Tablet.

You are not recommended to take ibuprofen with Rasilez 300 mg Tablet as co-administration of these two medicines may reduce the effect of Rasilez 300 mg Tablet and increase the risk of impaired kidney function. However, if you experience loss of appetite, sudden weight loss or weight gain, weakness, muscle cramps, vomiting, nausea, decreased or increased urination, irregular heart rhythm and fluid retention, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Drug-Drug Interactions Checker List

  • ATORVASTATIN
  • FUROSEMIDE
  • TORASEMIDE
  • KETOCONAZOLE
  • CYCLOSPORINE
  • IBUPROFEN
  • NAPROXEN
  • LISINOPRIL
  • ENALAPRIL
  • RAMIPRIL
  • VERAPAMIL
  • TELMISARTAN
  • VALSARTAN
  • IRBESARTAN

Special Advise

  • Your blood pressure, kidney function, and the amount of electrolytes (e.g. potassium) in your blood may be monitored by your doctor at regular intervals.

Disease/Condition Glossary

Essential hypertension: It is high blood pressure without a known secondary cause. Hypertension (high blood pressure) is a medical condition in which the blood pressure is elevated persistently in the arteries. High blood pressure is mostly caused by obesity, diabetes, smoking, high salt intake, stress, lack of physical activity, or ageing. Normal blood pressure lies between 90/60 mmHg and 120/80 mmHg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure. If it is left untreated, it may lead to heart disease and stroke. 

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