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  3. R-Cin 300 Capsule 10's

R-Cin 300 Capsule 10's, Pack of 10 CAPSULES
R-Cin 300 Capsule 10's, Pack of 10 CAPSULES
Not for online sale
Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

RIFAMPICIN-300MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About R-Cin 300 Capsule

R-Cin 300 Capsule belongs to the group of medicines called macrolide antibiotics, primarily used in combination with other medicines to treat tuberculosis (TB). Tuberculosis is an infectious respiratory disease that affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It is also used to treat other bacterial infections. R-Cin 300 Capsule does not work against infections caused by the virus, including cold and flu. As R-Cin 300 Capsule is an antibiotic, it does not work against infections caused by the virus, including cold and flu. The bacteria causing tuberculosis (TB) are highly contagious that spread from one person to another via tiny droplets released into the air (through coughs or sneezes).

R-Cin 300 Capsule consists of a drug called 'rifampicin' which works by inactivating a bacterial protein enzyme (RNA-polymerase) and inhibits bacterial cell death.  R-Cin 300 Capsule acts against the bacteria called Mycobacterium tuberculosis, which causes TB (tuberculosis). 

R-Cin 300 Capsule should be taken as recommended by your doctor. It should be taken 30 minutes before food or 2 hours after food on an empty stomach. In some cases, you may experience certain common side effects, such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhea, gas, and numbness or tingling sensation. Most of these side effects are mild and subside over time. However, if any of these effects persist contact your doctor immediately.

R-Cin 300 Capsule may raise liver enzymes like ALT and can cause jaundice if taken longer. Hence, a regular liver function test (LFT) is recommended while taking treatment with R-Cin 300 Capsule . Maintain a gap of one hour between R-Cin 300 Capsule and antacid medicines. R-Cin 300 Capsule is not recommended if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking R-Cin 300 Capsule as it passes into breast milk. R-Cin 300 Capsule may cause dizziness, and vision problems; hence avoid driving vehicles or operating machines that require mental concentration. Avoid alcohol consumption while taking R-Cin 300 Capsule as it could lead to increased drowsiness, dizziness, and liver damage.

Uses of R-Cin 300 Capsule

Tuberculosis (TB)

Directions for Use

Tablet/Capsule: Take R-Cin 300 Capsule 30 minutes before or 2 hours after food on an empty stomach. Swallow R-Cin 300 Capsule as a whole; do not crush or chew the tablet/capsule. The dose and duration of R-Cin 300 Capsule can vary depending on your condition and the severity of the infection.Dispersible tablet (DT): Before taking this, take a glass of water and disperse the tablet in it and then drink it.Suspension: Shake the bottle well. It can be taken 30 minutes before or 2 hours after food on an empty stomach. The dose and duration of R-Cin 300 Capsule can vary depending upon your condition and severity of the infection.

Medicinal Benefits

R-Cin 300 Capsule contains 'Rifampicin' that treats Tuberculosis (TB) by inactivating a bacterial genetic material that allows TB bacteria to make a copy of its protein for further growth inside the host cell (human). R-Cin 300 Capsule is active against gram-positive cocci bacteria like Mycobacteria, Clostridium difficle and gram-negative bacteria like Neisseria meningitides, N. gonorrhoeae and Hemophilus influenzae. R-Cin 300 Capsule is also used as a second-line treatment in the treatment of cholestatic pruritus. It also treats leprosy, severe gram-positive bacterial infections (like osteomyelitis, endocarditis, brain abscess, meningitis and implant infections) in combinations with other antibiotics. 

Storage

Store in a cool and dry place away from sunlight
Side effects of R-Cin 300 Capsule
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink plenty of fluids and stay hydrated.
  • Avoid foods containing sugars, salts and processed food.
  • Avoid consumption of alcohol.
  • Take healthy diet containing fiber, carbohydrates and lean proteins.
  • Exercise regularly and maintain a healthy lifestyle.
Managing Medication-Triggered Pancreatitis: A Step-by-Step Guide:
  • If you take medication and get severe stomach pain, feel nauseous, vomit, or have a fever, get emergency medical help right away. This could be a sign of pancreatitis, an inflammation of the pancreas.
  • Your doctor may alter your treatment plan, provide supportive therapy, or prescribe alternative medications to manage the reaction. They will also perform regular tests to monitor your progress and adjust your treatment as needed.
  • Follow your doctor's advice, including dietary recommendations and lifestyle changes, and avoid triggers like alcohol and fatty foods.
  • Monitor your condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug Warnings

R-Cin 300 Capsule should be avoided if you are allergic to any of its contents. Inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems on priority before starting treatment with R-Cin 300 Capsule . Avoid foods and drinks containing histamines or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while treating with R-Cin 300 Capsule as they might cause interaction. Maintain a gap of one hour between R-Cin 300 Capsule and antacid medicines.

R-Cin 300 Capsule is not recommended for pregnant women. Hence, inform your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while using R-Cin 300 Capsule as it passes into breast milk. R-Cin 300 Capsule should be given to children only if prescribed by the paediatrician. R-Cin 300 Capsule may cause dizziness or drowsiness, so avoid driving vehicles. Avoid alcohol consumption along with R-Cin 300 Capsule as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

verifiedApollotooltip
RifampicinDarunavir
Critical
RifampicinIndinavir
Critical

Drug-Drug Interactions

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RifampicinDarunavir
Critical
How does the drug interact with R-Cin 300 Capsule:
Taking darunavir with R-Cin 300 Capsule can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and R-Cin 300 Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinIndinavir
Critical
How does the drug interact with R-Cin 300 Capsule:
When Indinavir is taken with R-Cin 300 Capsule, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and R-Cin 300 Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinRanolazine
Critical
How does the drug interact with R-Cin 300 Capsule:
When ranolazine is taken with R-Cin 300 Capsule, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and R-Cin 300 Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinVoriconazole
Critical
How does the drug interact with R-Cin 300 Capsule:
Taking Voriconazole with R-Cin 300 Capsule can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with R-Cin 300 Capsule, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with R-Cin 300 Capsule:
Taking saquinavir with R-Cin 300 Capsule can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and R-Cin 300 Capsule, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinPirfenidone
Critical
How does the drug interact with R-Cin 300 Capsule:
Taking pirfenidone with R-Cin 300 Capsule can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and R-Cin 300 Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinDrospirenone
Severe
How does the drug interact with R-Cin 300 Capsule:
Taking drospirenone with R-Cin 300 Capsule can decrease the blood levels of drospirenone, which may make the medication less effective.

How to manage the interaction:
Although taking R-Cin 300 Capsule together with Drospirenone can result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue any medicine without consulting a doctor.
RifampicinLemborexant
Severe
How does the drug interact with R-Cin 300 Capsule:
Taking lemborexant with R-Cin 300 Capsule may reduce the blood levels of lemborexant, which may make the medication less effective in treating your condition.

How to manage the interaction:
Although taking R-Cin 300 Capsule together with Lemborexant can result in an interaction, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
RifampicinLeflunomide
Severe
How does the drug interact with R-Cin 300 Capsule:
Taking leflunomide with R-Cin 300 Capsule can increase the risk of liver problems.

How to manage the interaction:
Although taking R-Cin 300 Capsule together with Leflunomide can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience joint pain or swelling, unusual bleeding, fatigue, abdominal pain, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
RifampicinMycophenolic acid
Severe
How does the drug interact with R-Cin 300 Capsule:
When Mycophenolic acid is taken with R-Cin 300 Capsule, the amount of Mycophenolic acid in the blood may decrease, resulting in reduced effectiveness.

How to manage the interaction:
Taking Mycophenolic acid with R-Cin 300 Capsule together can result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take foods rich in vitamin C such as orange, kiwi, broccoli, and bell pepper which helps in improving the immune system. 
  • Avoid consuming processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine and beer.
  • Smoking and alcohol consumption should be avoided as it causes dizziness.
  • Drinking pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Author Details

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:31 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Do not stop taking R-Cin 300 Capsule despite symptomatic relief. To treat your condition effectually, continue taking R-Cin 300 Capsule for as long as it has been prescribed by doctor and must be taken strictly at proper times.

R-Cin 300 Capsule is a bactericidal drug that means it kills bacteria. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for bacterial survival, thereby killing the bacteria.

R-Cin 300 Capsule has no known serious drug interaction with ibuprofen or aspirin. Inform your doctor about all the medication you are currently taking to avoid harmful interactions that may reduce treatment effectiveness.

Yes, in some cases headache can be caused as a side effect of R-Cin 300 Capsule . A patient must consult a doctor if it progresses with time.

R-Cin 300 Capsule is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with R-Cin 300 Capsule . Please consult your doctor if you have any liver problems before taking R-Cin 300 Capsule as it may worsen the situation. However, prolonged use of R-Cin 300 Capsule can cause raised ALT (liver enzyme), and the person taking the treatment can developed jaundice symptoms like yellowing of eye, skin etc. In this case, stop taking R-Cin 300 Capsule and immediately contact a doctor.

R-Cin 300 Capsule may cause temporary discoloration of urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored. Contact your doctor for further advice.

Drug-Drug Interactions Checker List

  • ACETAMINOPHEN
  • HYDROCODONE
  • ERGOCALCIFEROL
  • ASCORBIC ACID
  • CHOLECALCIFEROL
  • WARFARIN
  • PANTOPRAZOLE
  • DOXYCYCLINE
  • CIPROFLOXACIN
  • AMOXICILLIN
  • DIPHENHYDRAMINE

Special Advise

  • R-Cin 300 Capsule may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
  • R-Cin 300 Capsule may cause temporary discolouration of urine, tears, and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discoloured. Contact your doctor for further advice.
  • Regular liver tests may be advised by your doctor while taking R-Cin 300 Capsule to check how your liver is functioning.
  • R-Cin 300 Capsule may affect test results of some blood tests such as folate, vitamin B12, and liver function tests. Hence inform your doctor or the lab person if any such tests are advised.

Disease/Condition Glossary

Tuberculosis (TB): It is an infectious disease that affects the lungs, but it could also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease that can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

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