R-Cinex 600 Tablet 3's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

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Whats That

About R-Cinex 600 Tablet

R-Cinex 600 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

R-Cinex 600 Tablet contains Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

In some cases, R-Cinex 600 Tablet may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Let your doctor know if your child is allergic to any of the components in R-Cinex 600 Tablet. Keep your doctor informed about your child's health condition and medications to rule out any side effects/interactions.

Uses of R-Cinex 600 Tablet

Tuberculosis.

Directions for Use

R-Cinex 600 Tablet should be given on an empty stomach, i.e., one hour prior or two hours after meals.Liquid: Administer the prescribed dose using a measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Medicinal Benefits

R-Cinex 600 Tablet belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. R-Cinex 600 Tablet contains two anti-mycobacterial agents, Rifampicin and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, R-Cinex 600 Tablet kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Side effects of R-Cinex 600 Tablet

Nerve Damage Causing Weakness, Pain And Numbness In Limbs

If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
Use compression socks and make sure to rest for a while to get relief from pain.
Avoid smoking and intake of alcohol or fluids that aggravate the pain.
Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Loose/ Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Redness Of The Skin

Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug Warnings

Do not give R-Cinex 600 Tablet to the child if he/she is allergic to any of the components in R-Cinex 600 Tablet, if he/she has acute liver disease, drug-induced liver disease, if the child has experienced liver damage linked to rifampicin or isoniazid, or if the child is taking anti-fungal (voriconazole) or medicines for HIV infection (protease inhibitors). R-Cinex 600 Tablet may cause liver damage; consult your doctor if the child experiences symptoms such as unexplained loss of appetite, nausea, vomiting, jaundice, dark urine, persistent fatigue for more than 3 days, abdominal pain and tenderness. Consult a doctor if your child gets flu-like symptoms such as headache, fever, or muscle ache. Inform the doctor if your child has HIV infection, epilepsy, psychiatric disorder, diabetes, porphyria, phenylketonuria (metabolic disorder), peripheral neuropathy (tingling sensation in hands and feet), kidney or liver problems, if your child is allergic to ethionamide or niacin (nicotinic acid), or if your child is taking cortisone or any cortisone-like drug.

Drug-Drug Interactions

IsoniazidLomitapide

Critical

IsoniazidRegorafenib

Critical

Drug-Drug Interactions

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IsoniazidLomitapide

Critical

How does the drug interact with R-Cinex 600 Tablet:
When Lomitapide is taken with R-Cinex 600 Tablet, R-Cinex 600 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.

IsoniazidRegorafenib

Critical

How does the drug interact with R-Cinex 600 Tablet:
When R-Cinex 600 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with R-Cinex 600 Tablet is not recommended, it taken can be taken if prescribed by the doctor.

IsoniazidLovastatin

Critical

How does the drug interact with R-Cinex 600 Tablet:
When Lovastatin is taken with R-Cinex 600 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking R-Cinex 600 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.

RifampicinPirfenidone

Critical

How does the drug interact with R-Cinex 600 Tablet:
Taking pirfenidone with R-Cinex 600 Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinRanolazine

Critical

How does the drug interact with R-Cinex 600 Tablet:
When ranolazine is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinSaquinavir

Critical

How does the drug interact with R-Cinex 600 Tablet:
Taking saquinavir with R-Cinex 600 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinIndinavir

Critical

How does the drug interact with R-Cinex 600 Tablet:
When Indinavir is taken with R-Cinex 600 Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinVoriconazole

Critical

How does the drug interact with R-Cinex 600 Tablet:
Taking Voriconazole with R-Cinex 600 Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with R-Cinex 600 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinDarunavir

Critical

How does the drug interact with R-Cinex 600 Tablet:
Taking darunavir with R-Cinex 600 Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and R-Cinex 600 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

IsoniazidOmeprazole

Severe

How does the drug interact with R-Cinex 600 Tablet:
When Omeprazole is taken with R-Cinex 600 Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Omeprazole with R-Cinex 600 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help in improving the immune system.
Avoid processed and fried foods.
Warm ginger tea or warm soup can help in providing relief from cough.

Side Effects of R-Cinex 600 Tablet

Nausea
Vomiting
Diarrhoea
Stomach pain
Loss of appetite

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:48 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does R-Cinex 600 Tablet work?

R-Cinex 600 Tablet works by killing Mycobacterium tuberculosis which causes TB (tuberculosis).

Does R-Cinex 600 Tablet cause discolouration of tears?

R-Cinex 600 Tablet may cause reddish-orange discolouration of body fluids such as tears, sputum and urine; this is not harmful and does not require medical attention. However, consult your doctor if you have any concerns.

Does R-Cinex 600 Tablet stain contact lens?

R-Cinex 600 Tablet might stain soft contact lenses. The child should use spectacles and avoid wearing contact lens while taking R-Cinex 600 Tablet.

Drug-Drug Interactions Checker List

VORICONAZOLE
SAQUINAVIR
RITONAVIR
DISULFIRAM

Disease/Condition Glossary

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight.