Can I stop taking RCINEX R CIN + INH 450MG CAPSULE on my own?

Do not stop taking RCINEX R CIN + INH 450MG CAPSULE despite symptomatic relief. To treat your condition effectually, continue taking RCINEX R CIN + INH 450MG CAPSULE for as long as it has been prescribed for you.

Can I take antacids with RCINEX R CIN + INH 450MG CAPSULE?

Do not take RCINEX R CIN + INH 450MG CAPSULE along with antacids as it might decrease the effectiveness of RCINEX R CIN + INH 450MG CAPSULE. Maintain a minimum gap of 1hour between both.

Can I take RCINEX R CIN + INH 450MG CAPSULE with other TB medicines?

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE with other medicines. Medicines used to treat TB such as PAS (P-amino salicylic acid) and cycloserine should be taken 8hours apart from RCINEX R CIN + INH 450MG CAPSULE.

What foods should I avoid while taking RCINEX R CIN + INH 450MG CAPSULE?

RCINEX R CIN + INH 450MG CAPSULE contains isoniazid which might interact with foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer. Avoid these foods while taking RCINEX R CIN + INH 450MG CAPSULE.

Does RCINEX R CIN + INH 450MG CAPSULE affect contraception?

RCINEX R CIN + INH 450MG CAPSULE might decrease the effectiveness of oral contraceptives (birth control pills). This could lead to an unplanned pregnancy. Instead, use a reliable barrier method of contraception such as condoms or the coil while taking RCINEX R CIN + INH 450MG CAPSULE. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.

Does RCINEX R CIN + INH 450MG CAPSULE cause discolouration of teeth?

RCINEX R CIN + INH 450MG CAPSULE may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking RCINEX R CIN + INH 450MG CAPSULE. Do not worry as it is a common side-effect of RCINEX R CIN + INH 450MG CAPSULE.

Does RCINEX R CIN + INH 450MG CAPSULE stain contact lens?

Yes, RCINEX R CIN + INH 450MG CAPSULE might permanently stain soft contact lenses. Use spectacles and avoid wearing contact lens while taking RCINEX R CIN + INH 450MG CAPSULE.

Does RCINEX R CIN + INH 450MG CAPSULE affect diagnostic test results?

RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.

Does RCINEX R CIN + INH 450MG CAPSULE cause liver problems?

Yes, RCINEX R CIN + INH 450MG CAPSULE may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking RCINEX R CIN + INH 450MG CAPSULE to check how your liver is functioning.

RCINEX R CIN + INH 450MG CAPSULE

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Not for online sale

MRP ₹128.5

(Inclusive of all Taxes)

₹19.3 Cashback (15%)

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Prescription drug

Whats That

About RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).

In some cases, you may experience certain common side-effects such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Uses of RCINEX R CIN + INH 450MG CAPSULE

Tuberculosis.

Directions for Use

Take RCINEX R CIN + INH 450MG CAPSULE 30 minutes before food or 2 hours after food. Swallow RCINEX R CIN + INH 450MG CAPSULE as a whole; do not crush or chew it.

Key Benefits

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Storage

Store in a cool and dry place away from sunlight

Side effects of Rcinex R Cin + Inh 450mg Capsule

Burning Or Tingling Sensation

Change positions or take a break from activity to relieve symptoms.
Avoid postures that put a lot of pressure on just one area of the body.
If you have vitamin deficiency, take supplements or change your diet.
Exercise regularly like cycling, walking or swimming.
Avoid sitting with your legs crossed.
Clench and unclench your fists and wiggle your toes.
Massage the affected area.

Abnormal liver function test

High levels of liver enzymes need immediate medical attention.
Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
Regularly do strengthening exercises to control your cholesterol levels.
Avoid drinking alcohol as it can affect your liver.
Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
Practice yoga and meditation to improve liver functioning and overall health.

Reddening Of The Face

Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:

Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Reddish-brown urine color change

Sputum

Tears

Avoid rubbing your eyes, which can exacerbate the issue.
Lubricate your eyes using artificial tears or eye drops.
Wear sunglasses while you are out in the sun to protect your eyes from sun and wind.
Avoid irritants like smoke, dust, and strong chemicals.
Get enough rest and sleep to help your eyes recover.

Changes In The Amount Of Saliva Produced

Inform your doctor about changes in saliva levels. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not take RCINEX R CIN + INH 450MG CAPSULE if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting RCINEX R CIN + INH 450MG CAPSULE, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

RifampicinSaquinavir

Critical

RifampicinIndinavir

Critical

Drug-Drug Interactions

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RifampicinSaquinavir

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking saquinavir with Rcinex R Cin + Inh 450mg Capsule can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinIndinavir

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Indinavir is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinPirfenidone

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking pirfenidone with Rcinex R Cin + Inh 450mg Capsule can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinDarunavir

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking darunavir with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinVoriconazole

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking Voriconazole with Rcinex R Cin + Inh 450mg Capsule can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Rcinex R Cin + Inh 450mg Capsule, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RifampicinRanolazine

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When ranolazine is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

IsoniazidRegorafenib

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Rcinex R Cin + Inh 450mg Capsule is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Rcinex R Cin + Inh 450mg Capsule is not recommended, it taken can be taken if prescribed by the doctor.

IsoniazidLomitapide

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lomitapide is taken with Rcinex R Cin + Inh 450mg Capsule, Rcinex R Cin + Inh 450mg Capsule may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.

IsoniazidLovastatin

Critical

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lovastatin is taken with Rcinex R Cin + Inh 450mg Capsule, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lovastatin is not recommended but can be taken if a doctor has prescribed it.

RifampicinBedaquiline

Severe

How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking bedaquiline with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of bedaquiline, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between bedaquiline and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food

Moderate

Drug-Food Interactions

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ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food

Moderate

Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Coadministration of Rcinex R Cin + Inh 450mg Capsule with foods containing tyramine increases the risk of side effects such as headache, sweating, diarrhea, nausea, vomiting, fast heartbeats, difficulty breathing, and low blood pressure. Avoid foods containing tyramine while being treated with Rcinex R Cin + Inh 450mg Capsule , as it can lead to side effects.

Diet & Lifestyle Advise

Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system.
Avoid processed and fried foods.
Warm ginger tea or warm soup can help in providing relief from cough.
Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
Quit smoking and avoid alcohol consumption.

Side Effects of RCINEX R CIN + INH 450MG CAPSULE

Drowsiness
Dizziness
Headache
Weakness
Muscle pain
Heartburn
Diarrhoea
Gas
Numbness

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:30 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

SAQUINAVIR
RITONAVIR
ACETAMINOPHEN
HYDROCODONE
DULOXETINE
BUPROPION
DILTIAZEM
ETHAMBUTOL
PYRAZINAMIDE
CHOLECALCIFEROL
ERGOCALCIFEROL

Special Advise

RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.
Your doctor may advise you to get regular liver tests while taking RCINEX R CIN + INH 450MG CAPSULE to check how your liver is functioning.

Disease/Condition Glossary

Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it could also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.