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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

AMINOPHYLLINE-400MG

Manufacturer/Marketer :

Regaine Laboratories

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Regain Aminophylin Injection

Regain Aminophylin Injection belongs to the class of drugs called bronchodilators. It is indicated for the relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease. Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Regain Aminophylin Injection contains Aminophylline, which helps to provide relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, thereby it making breathing easier.

Regain Aminophylin Injection is usually administered by a qualified healthcare professional; do not self-administer. Regain Aminophylin Injection may cause certain side effects, including upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability. Most of these side effects of Regain Aminophylin Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before prescribing the Regain Aminophylin Injection, let your doctor know about all your medical conditions, allergic reactions, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Regain Aminophylin Injection may cause insomnia and restlessness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Uses of Regain Aminophylin Injection

Asthma, Chronic obstructive pulmonary disease (COPD)

Directions for Use

Regain Aminophylin Injection will be administered by a trained healthcare professional. Do not self-administer.

Medicinal Benefits

Regain Aminophylin Injection contains Aminophylline. It belongs to the class of drugs called bronchodilators. It is indicated to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease. Aminophylline relaxes and opens air passages in the lungs, making breathing easier. Besides this, it relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Regain Aminophylin Injection

  • Upset stomach
  • Stomach pain
  • Diarrhea
  • Headache
  • Restlessness
  • Insomnia
  • Irritability
  • Injection site reactions

Drug Warnings

Before receiving Regain Aminophylin Injection, let your doctor know about all your medical conditions, such as if you have or have ever had seizures, heart disease, an overactive or underactive thyroid gland, high blood pressure, or kidney or liver disease or if you have a history of alcohol abuse, allergic reactions (especially aminophylline, theophylline’s, theobromine, caffeine or to any of the excipients present in Regain Aminophylin Injection), and all medication history you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before receiving Regain Aminophylin Injection. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
AminophyllineMetoprolol
Severe

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Regain Aminophylin Injection 10ml with Riociguat may significantly lower your blood pressure.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with Riociguat can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetoprolol
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Regain Aminophylin Injection 10ml with Metoprolol together can make metoprolol less effective and increase the effects of Regain Aminophylin Injection 10ml.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with Metoprolol may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetoprolol Tartrate
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Co-administration of Regain Aminophylin Injection 10ml with Metoprolol could increase the effects of Regain Aminophylin Injection 10ml and decrease the effects of Metoprolol.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with Metoprolol can cause an interaction, it can be taken only if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineBisoprolol
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Co-administration of Regain Aminophylin Injection 10ml with Bisoprolol could reduce the metabolism of Regain Aminophylin Injection 10ml which increased the levels and enhance the effects of Regain Aminophylin Injection 10ml.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml and bisoprolol together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllinePropranolol
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Regain Aminophylin Injection 10ml with Propranolol together can make propranolol less effective and increase the effects of Regain Aminophylin Injection 10ml.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with Propranolol can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineTramadol
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Tramadol with Regain Aminophylin Injection 10ml can increase the risk of cause seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml and tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as seizures, dizziness, drowsiness, or difficulty concentrating, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
AminophyllineEnoxacin
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Regain Aminophylin Injection 10ml with Enoxacin together could increase the levels and enhance the effects of Regain Aminophylin Injection 10ml leading to increased risk or severity of side effects.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with enoxacin can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, headache, insomnia, seizures, or heart palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineDeferasirox
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Combining Regain Aminophylin Injection 10ml with Deferasirox may significantly increase the blood levels of Regain Aminophylin Injection 10ml.

How to manage the interaction:
Taking Regain Aminophylin Injection 10ml with Deferasirox can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, loss of appetite, headache, confusion, restlessness, sleeplessness, fits, heart palpitations, or irregular heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineMetrizamide
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Coadministration of Metrizamide with Regain Aminophylin Injection 10ml can increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Co-administration of Regain Aminophylin Injection 10ml with Metrizamide can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AminophyllineBupropion
Severe
How does the drug interact with Regain Aminophylin Injection 10ml:
Bupropion is capable of causing seizures in rare cases, and combining it with Regain Aminophylin Injection 10ml, may enhance the risk.

How to manage the interaction:
Co-administration of bupropion along with Regain Aminophylin Injection 10ml can lead to interaction; it can be taken if recommended by a doctor. Avoid tasks that need mental attention, such as driving or operating dangerous machinery, until you have a better understanding of how the medications impact you. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet specially green leafy vegetables, and strictly do not consume alcohol or caffeine (coffee, tea and cola drinks and chocolate).
  • Drink plenty of fluids daily to thin mucus, making it easier to cough out.
  • Smoking should be avoided while receiving Regain Aminophylin Injection as it can alter the blood levels of aminophylline, which may affect the dosing.
  • It is very important to maintain hygiene, like washing hands after coming from outside, as people with asthma/COPD are at a greater risk of infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

Habit Forming

No

Therapeutic Class

BRONCHODILATOR

Drug-Diseases Interactions

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AMINOPHYLLINE-400MGPeptic ulcer, site unspecified
Severe
AMINOPHYLLINE-400MGOther disorders of kidney and ureter, not elsewhere classified
Severe

Drug-Diseases Interactions

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AMINOPHYLLINE-400MGPeptic ulcer, site unspecified
Severe
How does the disease interact with Regain Aminophylin Injection 10ml:
methylxanthines should be administered with extreme caution in patients with active peptic ulcer disease.

How to manage the interaction:
Regain Aminophylin Injection 10ml therapy is not recommended in patients with peptic ulcer disease as it stimulates acid secretion in the stomach. However, it can be taken if your doctor has advised it. If you experience symptoms such as nausea, vomting, pain or discomfort in stomach, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-400MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Regain Aminophylin Injection 10ml:
theophyllines should be administered cautiously in patients with impaired renal function.

How to manage the interaction:
Regain Aminophylin Injection 10ml therapy is not recommended in patients with kidney disease as it can get accumulated and lead to increased risk or severity of Regain Aminophylin Injection 10ml side effects. It can be taken if your doctor has advised it. However, if you experience any symptoms like nausea, vomiting, dizziness, fatigue, sleeplessness, irritability, headache, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-400MGConvulsions, not elsewhere classified
Severe
How does the disease interact with Regain Aminophylin Injection 10ml:
The use of theophylline's is contraindicated in patients with seizure disorders.

How to manage the interaction:
Regain Aminophylin Injection 10ml therapy is not recommended in patients with a history of seizures or head trauma as it can increase the risk or severity of seizures which can be fatal. It can be taken if your doctor has advised it. However, if you experience any symptoms like nausea, vomiting, dizziness, fatigue, sleeplessness, irritability, headache, jerking movements of arms or legs, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-400MGGastro-oesophageal reflux disease
Moderate
How does the disease interact with Regain Aminophylin Injection 10ml:
methylxanthines should be administered cautiously in patients with significant gastroesophageal reflux.

How to manage the interaction:
Regain Aminophylin Injection 10ml therapy is not recommended in patients with gastric disease as it stimulates acid secretion in the stomach. However, it can be taken if your doctor has advised it. If you experience symptoms such as nausea, vomting, pain or discomfort in stomach, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-400MGCare involving dialysis
Moderate
How does the disease interact with Regain Aminophylin Injection 10ml:
Theophylline is removed by hemodialysis. Doses should either be scheduled for administration after dialysis or supplemental doses be given after dialysis.

How to manage the interaction:
Patients receiving dialysis are not advised to use Regain Aminophylin Injection 10ml because it can be eliminated during the procedure. Dialysis should be secluded before taking the Regain Aminophylin Injection 10ml dose. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-400MGOther cardiac arrhythmias
Moderate
How does the disease interact with Regain Aminophylin Injection 10ml:
theophyllines should be administered caution in patients with tachyarrhythmias.

How to manage the interaction:
Regain Aminophylin Injection 10ml therapy is not recommended in patients with a risk of cardiac diseases, or high or low blood pressure, as this can increase the possibility or severity of side effects.

FAQs

Regain Aminophylin Injection contains Aminophylline, a bronchodilator that works by relaxing and widening the muscles of the airways, thereby making it easier for asthma and COPD patients to breathe easily.

Avoid aerated drinks, fried foods, excess salts (sodium chloride or table salt), dairy products, cruciferous veggies, cold cuts and cured meats. Besides this, avoid consuming high amounts of caffeine-containing tea, coffee, chocolate and cola as this food already consists of aminophylline, an active constituent of Regain Aminophylin Injection. Sulfites in alcoholic beverages can trigger symptoms of asthma and COPD, so avoid consuming alcoholic beverages.

No, you are not recommended to smoke while receiving Regain Aminophylin Injection as it may reduce the effectiveness of Regain Aminophylin Injection and damage your lung's airways (alveoli). Long-term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.

Regain Aminophylin Injection should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Regain Aminophylin Injection so that the dose may be adjusted or an alternate medicine may be prescribed.

No, Regain Aminophylin Injection does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

You are not recommended to take Regain Aminophylin Injection with antibiotics such as erythromycin, tetracycline, amoxicillin, amikacin and gentamicin at the same time as it may reduce the effectiveness of antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of a minimum of 2 hours between taking Regain Aminophylin Injection and antibiotics. However, please consult a doctor before using Regain Aminophylin Injection with antibiotics or other medicines.

Drug-Drug Interactions Checker List

  • CIMETIDINE
  • ERYTHROMYCIN
  • CIPROFLOXACIN
  • FLUCONAZOLE
  • ALLOPURINOL
  • DILTIAZEM
  • PROPRANOLOL
  • FLUVOXAMINE
  • PHENYTOIN
  • CARBAMAZEPINE
  • FUROSEMIDE

Special Advise

  • The doctor may suggest some tests to know the root cause of the respiratory disorder, such a Spirometry (check the narrowing of bronchial tubes) and Peak flow (check how difficult it is to exhale).
  • Please avoid the use of Tobacco and Marijuana as it decreases the efficacy of Regain Aminophylin Injection. 
  • If you have a glucose test or lipid profile test, let your doctor know about this, as prolonged use of Regain Aminophylin Injection may increase glucose levels and free fatty acid in the body. 

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than two times a week and up to 4 nights a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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