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  3. REGULATE 5MG TABLET

Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

NORETHISTERONE-5MG

Manufacturer/Marketer :

Group Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About REGULATE 5MG TABLET

REGULATE 5MG TABLET belongs to the class of medicines called progestogens used to treat heavy, painful, or irregular periods, premenstrual syndrome (PMS), and endometriosis. Additionally, REGULATE 5MG TABLET may be used in the treatment of breast cancer. Endometriosis is a disorder in which the uterus's tissue lining (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain.

REGULATE 5MG TABLET contains Norethisterone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Take REGULATE 5MG TABLET as prescribed by your doctor. You are advised to take REGULATE 5MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience unusual vaginal bleeding or spotting, dizziness, dry mouth, constipation, nausea, diarrhea, headache, breast pain, and tenderness. Most of these side effects of REGULATE 5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to REGULATE 5MG TABLET or any other medicines, please tell your doctor. REGULATE 5MG TABLET is not recommended for pregnant women as it may harm the unborn baby. If you are breastfeeding, consult a doctor before taking REGULATE 5MG TABLET. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking REGULATE 5MG TABLET. You are advised to stop smoking while taking REGULATE 5MG TABLET as it may increase the risk of adverse effects.

Uses of REGULATE 5MG TABLET

Heavy, painful or irregular periods, Premenstrual syndrome (PMS), Endometriosis, Breast cancer

Directions for Use

Take REGULATE 5MG TABLET with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

REGULATE 5MG TABLET contains Norethisterone, a synthetic hormone that mimics the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to REGULATE 5MG TABLET or any other medicines, please tell your doctor. REGULATE 5MG TABLET is not recommended for pregnant women as it may harm an unborn baby. If you are breastfeeding, consult a doctor before taking REGULATE 5MG TABLET. It is advised to use effective non-hormonal contraceptives such as condoms to avoid pregnancy while taking REGULATE 5MG TABLET. You are advised to stop smoking while taking REGULATE 5MG TABLET as it may increase the risk of adverse effects. If you are about to undergo any surgery, please inform your doctor that you are taking REGULATE 5MG TABLET as it may increase the effect of certain anesthetics. If you experience sudden shortness of breath, rapid heartbeat, sudden, severe, sharp pain in the chest, or cough up blood, stop taking REGULATE 5MG TABLET and consult a doctor immediately as these might be signs of a blood clot in the lungs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Regulate 5mg Tablet:
Coadministration of Regulate 5mg Tablet and primidone can reduce the blood levels and effects of Regulate 5mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Regulate 5mg Tablet and Primidone, they can be taken together if prescribed by a doctor. However, if you experience abnormal bleeding, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regulate 5mg Tablet:
Coadministration of Regulate 5mg Tablet with Tizanidine can cause drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, fainting.

How to manage the interaction:
Taking Regulate 5mg Tablet with Tizanidine together can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NorethisteroneEtretinate
Severe
How does the drug interact with Regulate 5mg Tablet:
Using Etretinate and Regulate 5mg Tablet together can cause severe, birth defects. Never use etretinate if you are pregnant. Both a primary and a secondary form of birth control must be used together and for at least 3 years after stopping therapy.

How to manage the interaction:
Although taking Regulate 5mg Tablet and Etretinate together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, make sure to contact your doctor right away. These symptoms may be related to your birth control. Do not stop using any medications without a doctor's advice.
How does the drug interact with Regulate 5mg Tablet:
Taking carbamazepine and Regulate 5mg Tablet may possibly reduce the effects of Regulate 5mg Tablet which may result in higher risk of breakthrough bleeding and unexpected pregnancy.

How to manage the interaction:
Although taking carbamazepine and Regulate 5mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Contact your doctor if you experience hot flashes, vaginal dryness, or uncontrolled bleeding. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regulate 5mg Tablet:
The combined use of Regulate 5mg Tablet and phenobarbital can reduce the blood levels and effects of Regulate 5mg Tablet.

How to manage the interaction:
Although taking phenobarbital and Regulate 5mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. If you experience any symptoms like abnormal bleeding, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Regulate 5mg Tablet:
Using tranexamic acid together with norethindrone may increase the risk of blood clots.

How to manage the interaction:
Taking Regulate 5mg Tablet with tranexamic acid can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg, contact a doctor immediately .Do not discontinue any medications without consulting a doctor.
NorethisteroneBexarotene
Severe
How does the drug interact with Regulate 5mg Tablet:
Coadministration of Bexarotene and Regulate 5mg Tablet together can decrease the effectiveness of norethindrone and increase the risk of unintended pregnancy.

How to manage the interaction:
Combining Bexarotene with Regulate 5mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like increased hot flashes, vaginal dryness, or menstrual abnormalities, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regulate 5mg Tablet:
Taking griseofulvin with Regulate 5mg Tablet may reduce blood levels and the effects of Regulate 5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Griseofulvin and Regulate 5mg Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Regulate 5mg Tablet:
Co-administration of Regulate 5mg Tablet with Bosentan can reduce the blood levels and effects of norethindrone.

How to manage the interaction:
Taking Regulate 5mg Tablet with Bosentan together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Regulate 5mg Tablet:
Coadministration of Acitretin with Regulate 5mg Tablet may interfere with the contraceptive effect of Regulate 5mg Tablet.

How to manage the interaction:
Acitretin and Regulate 5mg Tablet should be used together only if prescribed by your doctor. Use of at least two methods of effective contraception is mandatory during acitretin therapy and for at least 3 years after stopping therapy.

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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NORETHISTERONE-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice may increase the blood levels of Regulate 5mg Tablet. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Regulate 5mg Tablet dose. Avoid or limit the consumption of grapefruit and grapefruit juice while taking the Regulate 5mg Tablet dose.

Diet & Lifestyle Advise

  • Avoid fried and processed foods.
  • Include fiber-rich foods like whole grains, fruits, and vegetables in your diet.
  • Avoid refined carbohydrates that are high in sugars.
  • Replace animal proteins (like eggs, fish, and meat) with vegetable protein sources (nuts, seeds, and beans).
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, do moderate exercise regularly.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

PROGESTIN

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

REGULATE 5MG TABLET contains Norethisterone, a synthetic hormone that works by mimicking the activity of the natural hormone progesterone. Thereby, it restores hormone levels in the body and regulates the growth and shedding of the womb lining. Thus, it helps to treat menstrual disorders.

REGULATE 5MG TABLET may be used to delay periods. REGULATE 5MG TABLET keeps progesterone levels high and prevents shedding of the womb lining. However, please consult a doctor before using REGULATE 5MG TABLET.

REGULATE 5MG TABLET may increase the risk of a blood clot in the veins of the leg, especially if you are overweight, smoking, or have a history of a blood clot in the lungs or veins, repeated miscarriage or have major surgery, serious injury, or systemic lupus erythematosus (autoimmune disease). Therefore, please inform your doctor if you have any of these conditions before taking REGULATE 5MG TABLET.

You are not recommended to take REGULATE 5MG TABLET with rifampicin as it may decrease the levels of REGULATE 5MG TABLET in blood and reduce its effectiveness. However, please consult a doctor before taking REGULATE 5MG TABLET with other medicines.

Periods usually resume within 3 days of discontinuing REGULATE 5MG TABLET. However, please consult a doctor if you have any concerns regarding this.

REGULATE 5MG TABLET may cause changes in blood sugar levels. Therefore, it is advised to regularly monitor blood sugar levels while taking REGULATE 5MG TABLET and inform your doctor if you have diabetes before taking REGULATE 5MG TABLET.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • NELFINAVIR
  • RITONAVIR
  • AMINOGLUTETHIMIDE
  • COTRIMOXAZOLE
  • RIFAMPICIN
  • TETRACYCLINE
  • CICLOSPORIN

Special Advise

  • REGULATE 5MG TABLET may interfere with certain laboratory tests. Therefore, inform your doctor that you are taking REGULATE 5MG TABLET before undergoing any tests.

Disease/Condition Glossary

Endometriosis: It is a disorder in which the tissue lining the uterus (endometrium) grows on the ovaries, bowel, or tissues lining the pelvis. The most common symptom is pelvic pain. Other symptoms of endometriosis include lower back pain, painful periods, heavy menstrual bleeding, pain following sexual intercourse, or discomfort with bowel movements. 

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