apollo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
Insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
  1. Home
  2. Medicine

  3. Relicalm Plus 10 mg Tablet 10's

Relicalm Plus 10 mg Tablet 10's, Pack of 10 TabletS
Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
Non returnable*
Know More
COD available

Online payment accepted

rxMedicinePrescription drug

Whats That

tooltip

Composition :

TRIFLUOPERAZINE-10MG + TRIHEXYPHENIDYL-2MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Relicalm Plus 10 mg Tablet

Relicalm Plus 10 mg Tablet belongs to a class of drugs called 'antipsychotics' used to prevent and treat schizophrenia (a mental illness). Additionally, Relicalm Plus 10 mg Tablet may be used to anxiety and depression over a short period. Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. Depression is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do.

Relicalm Plus 10 mg Tablet combination composed of two different medicines, namely, Trifluoperazine and Trihexyphenidyl. Trifluoperazine inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behaviour, and emotions. Thereby, Relicalm Plus 10 mg Tablet helps in controlling psychotic illness, relieving depression, lightening the mood, and relieving anxiety symptoms such as fear and panic. On the other hand, Trihexyphenidyl is an anticholinergic agent that acts on the nervous system and corrects some of the chemical imbalances that cause some side effects such as shaking of hands and muscle spasms due to Trifluoperazine.

Take Relicalm Plus 10 mg Tablet as prescribed by your doctor. You are advised to take Relicalm Plus 10 mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience nausea, constipation, dryness in the mouth, sedation, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, increased prolactin level in the blood, dizziness, blurred vision, and nervousness. Most of these side effects of Relicalm Plus 10 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Relicalm Plus 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Relicalm Plus 10 mg Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Relicalm Plus 10 mg Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Avoid consuming alcohol along with Relicalm Plus 10 mg Tablet as it could lead to increased drowsiness and dizziness. Consult your doctor before giving this medicine to your child. Keep your doctor informed about your medicines and health condition and rule out any side effects. 

Uses of Relicalm Plus 10 mg Tablet

Schizophrenia, Anxiety, Depression

Directions for Use

Swallow Relicalm Plus 10 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Relicalm Plus 10 mg Tablet combination composed of two different medicines, namely; Trifluoperazine and Trihexyphenidyl used to prevent and treat relapses of schizophrenia (a mental illness). Additionally, Relicalm Plus 10 mg Tablet may be used to anxiety and depression over a short period. Trifluoperazine inhibits the dopamine (chemical messenger) receptors in the brain. Dopamine is involved in regulating mood, behavior, and emotions. Thereby, Relicalm Plus 10 mg Tablet helps in controlling psychotic illness, relieving depression, lighten the mood, and relieve anxiety symptoms such as fear and panic. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms, etc.). On the other hand, Trihexyphenidyl is used to treat and prevent side effects such as involuntary movements (shaking of hands, muscle spasms) caused by Trifluoperazine. Trihexyphenidyl exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Relicalm Plus 10 mg Tablet improves muscle control and reduces stiffness, thereby helps the muscles move naturally. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Relicalm Plus 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Relicalm Plus 10 mg Tablet if you are pregnant, especially in the third trimester, as it may cause adverse effects in the baby such as breathing problems, muscle stiffness or weakness, shaking, etc. Please consult a doctor if you are pregnant or breastfeeding. Relicalm Plus 10 mg Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse reactions. Do not discontinue Relicalm Plus 10 mg Tablet on your own. Inform your doctor before taking Relicalm Plus 10 mg Tablet if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver, or kidney problems. Talk to your doctor immediately if you experience hallucinations. Relicalm Plus 10 mg Tablet may make you sweat less, making you more likely to get heatstroke. Avoid doing things that may cause you to overheat, such as hard work or exercise in hot weather or using hot tubs. When the weather is hot, drink a lot of fluids and dress lightly. Relicalm Plus 10 mg Tablet may cause drowsiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Relicalm Plus 10 mg Tablet as it could lead to increased drowsiness and dizziness. 

Drug-Drug Interactions

verifiedApollotooltip
TrihexyphenidylPotassium citrate
Critical
TrihexyphenidylPotassium chloride
Critical

Drug-Drug Interactions

Login/Sign Up

TrihexyphenidylPotassium citrate
Critical
How does the drug interact with Relicalm Plus 10 mg Tablet:
Co-administration of Relicalm Plus 10 mg Tablet with potassium citrate may increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Relicalm Plus 10 mg Tablet with potassium citrate is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, or black stools contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylPotassium chloride
Critical
How does the drug interact with Relicalm Plus 10 mg Tablet:
Co-administration of Relicalm Plus 10 mg Tablet with potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Relicalm Plus 10 mg Tablet with potassium chloride is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.
TrifluoperazineZiprasidone
Critical
How does the drug interact with Relicalm Plus 10 mg Tablet:
Co-administration of Relicalm Plus 10 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Relicalm Plus 10 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TrifluoperazineMetoclopramide
Critical
How does the drug interact with Relicalm Plus 10 mg Tablet:
Co-administration of Metoclopramide with Relicalm Plus 10 mg Tablet can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Metoclopramide with Relicalm Plus 10 mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping., contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylTopiramate
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Taking Relicalm Plus 10 mg Tablet with topiramate can increase the risk of increase body temperature and reduced sweating.

How to manage the interaction:
Co-administration of Relicalm Plus 10 mg Tablet with Topiramate can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience dizziness or lightheaded, increase body temperature contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
TrihexyphenidylKetamine
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Taking Relicalm Plus 10 mg Tablet with Ketamine can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Relicalm Plus 10 mg Tablet and ketamine, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrihexyphenidylAmantadine
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Coadministration of Allopurinol with Relicalm Plus 10 mg Tablet may increase side effects such as heat intolerance, dry mouth, confusion, constipation, difficulty urinating, and blurred vision especially in the elderly or those with a debilitating (physically weak) condition.

How to manage the interaction:
If you are supposed to take Allopurinol and Relicalm Plus 10 mg Tablet together, your doctor may adjust the dose or monitor you more frequently to safely use both medications.
TrihexyphenidylZonisamide
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Coadministration of Relicalm Plus 10 mg Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Relicalm Plus 10 mg Tablet with Zonisamide together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrihexyphenidylEsketamine
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Taking Relicalm Plus 10 mg Tablet with esketamine can increase the risk of other side effects.

How to manage the interaction:
Although there is a interaction between Relicalm Plus 10 mg Tablet and esketamine, but can be taken together if prescribed by your doctor. However, if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking contact your doctor right away. Do not stop using any medications without talking to your doctor.
TrifluoperazineMoxifloxacin
Severe
How does the drug interact with Relicalm Plus 10 mg Tablet:
Using moxifloxacin together with Relicalm Plus 10 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Relicalm Plus 10 mg Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - an irregular heart rhythm, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - call your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate, and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Relicalm Plus 10 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:38 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

FAQs

Relicalm Plus 10 mg Tablet contains Trifluoperazine and Trihexyphenidyl. Trifluoperazine is a typical antipsychotic which works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is used to treat and prevent side effects such as involuntary movements (shaking of hands, muscle spasms) caused by Trifluoperazine.

Dry mouth could be a side-effect of Relicalm Plus 10 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Antidepressants should be avoided while taking Relicalm Plus 10 mg Tablet as it might increase sedative effects. Consult your doctor before taking Relicalm Plus 10 mg Tablet if you are using depressants.

Relicalm Plus 10 mg Tablet can cause decreased sweating which results in rising in body temperature (hyperthermia). This serious side effect is greater in hot weather so it is advisable to drink plenty of water fluids, especially in summer. However, kidney patients should consult a doctor before drinking any fluid.

Hallucination is a medical condition in which the person may feel, hear or believe things that are not true, see things that are not there, feel unusually suspicious or confused. Trihexyphenidyl in Relicalm Plus 10 mg Tablet may cause hallucination in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Relicalm Plus 10 mg Tablet , please talk to your doctor immediately.

Relicalm Plus 10 mg Tablet should be avoided by dementia (decline in memory, behaviour, thinking and ability to do daily activities) patients as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you are suffering from dementia before taking Relicalm Plus 10 mg Tablet .

Drug-Drug Interactions Checker List

  • GUANETHIDINE
  • CODEINE
  • ATROPINE
  • PROCYCLIDINE
  • PROMAZINE
  • PROCHLORPERAZINE
  • CHLORPROMAZINE
  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • LAMOTRIGINE
  • CLONAZEPAM
  • PREGABALIN
  • LEVODOPA
  • WARFARIN
  • DESFERRIOXAMINE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • AMIODARONE
  • SOTALOL
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Special Advise

  • If you are going to have a special X-ray examination of the spinal cord or brain involving metrizamide (chemical), inform your doctor that you are taking Relicalm Plus 10 mg Tablet .
  • Blood tests are recommended while taking Relicalm Plus 10 mg Tablet to monitor blood counts and liver functioning.
  • This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. The symptoms include hallucinations, thought or movement disorders, delusions (misbelief), lack of emotion, sleep problems, isolation from family and friends and difficulty in doing daily activities.

Anxiety: It is a mental health disorder associated with fear, worry and excessive nervousness that may interfere with daily activities. The anxiety symptoms include feeling more stress than required for that event and lack of ability to set aside restlessness and worry. Anxiety can be treated by psychotherapy (meeting a psychologist) or medications.

Depression: It is a mood disorder associated with symptoms such as sadness, unable to sleep properly or enjoy life as you used to do.

Have a query?

Buy best C.n.s Drugs products by

whatsapp Floating Button
Buy Now
Add to Cart