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Religrast 300mcg Injection 0.5 ml

Religrast 300mcg Injection 0.5 ml

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Prescription drug
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Religrast 300mcg Injection 0.5 ml

Religrast 300mcg Injection 0.5 ml belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, bacterial infections or other conditions. Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections.

Religrast 300mcg Injection 0.5 ml contains ' Filgrastim ' that stimulates the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Religrast 300mcg Injection 0.5 ml is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection, and before stem cell donation.

You are advised to take Religrast 300mcg Injection 0.5 ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as thrombocytopenia (low platelets level), anaemia (low red blood cell), headache, diarrhoea, vomiting, nausea, alopecia (unusual hair loss), tiredness, soreness, swelling of the digestive tract, fever. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Religrast 300mcg Injection 0.5 ml for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Religrast 300mcg Injection 0.5 ml if you are pregnant or planning for pregnancy. Religrast 300mcg Injection 0.5 ml should not be taken by breastfeeding mothers unless prescribed. Religrast 300mcg Injection 0.5 ml should be given to children under strict medical supervision. Please tell your doctor before using Religrast 300mcg Injection 0.5 ml if you have sickle cell anaemia, as Religrast 300mcg Injection 0.5 ml may cause sickle cell crisis and osteoporosis (bone disease). Regular blood tests will be taken to monitor the number of white blood cells in the body. Inform your doctor about your health condition and medicines to rule out unpleasant side effects. Religrast 300mcg Injection 0.5 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees celsius else its efficacy might get lost. Do not store in the freezer or the fridge.

Uses of Religrast 300mcg Injection 0.5 ml

Neutropenia (low number of white blood neutropenia cells),  Neutropenia during Chemotherapy,  Neutropenia after Bone marrow transplantation,  Neutropenia in patients with HIV infection,  peripheral blood stem cell mobilisation (to stimulate stem cells to enter the bloodstream to be collected and used in bone marrow transplantation)

Medicinal Benefits

Religrast 300mcg Injection 0.5 ml contains ‘Filgrastim’ is a white blood cell growth factor. It belongs to a group of proteins called cytokines and is very similar to a natural protein (granulocyte-colony stimulating factor) produced by your body. Religrast 300mcg Injection 0.5 ml works by stimulating the bone marrow (the tissue where new blood cells are made) to produce more white blood cells that help fight infection. Religrast 300mcg Injection 0.5 ml is used to improve white blood cells during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells), neutropenia in patients with HIV infection and before stem cell donation.

Directions for Use

Religrast 300mcg Injection 0.5 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Religrast 300mcg Injection 0.5 ml

  • Thrombocytopenia (low platelets level)
  • Anaemia (low red blood cell)
  • Headache
  • Diarrhoea
  • Vomiting
  • Nausea
  • Alopecia (unusual hair loss)
  • Tiredness
  • Soreness and swelling of the digestive tract
  • Fever

Drug Warnings

Do not take Religrast 300mcg Injection 0.5 ml if you are allergic to Religrast 300mcg Injection 0.5 ml or any of its ingredients it may contain inactive ingredients (such as dry natural rubber/latex in the needle cover on the prefilled syringe), which can cause allergic reactions or other problems. Before starting treatment with Religrast 300mcg Injection 0.5 ml, inform your doctor if you have sickle cell anaemia, osteoporosis (bone disease), kidney disease, liver disease, spleen problems, heart problems, and radiation treatment. Religrast 300mcg Injection 0.5 ml can cause the spleen to become enlarged, and it could rupture (tear). Inform your doctor right away if you have sudden or severe pain in your left upper stomach spreading up to your shoulder. If you receive chemotherapy or bone marrow transplant, do not use Religrast 300mcg Injection 0.5 ml within 24 hours before or 24 hours after you receive chemotherapy or bone marrow transplant.  Do not take Religrast 300mcg Injection 0.5 ml if you are pregnant or breastfeeding unless prescribed by the doctor. Religrast 300mcg Injection 0.5 ml can be given safely to children only when prescribed. Religrast 300mcg Injection 0.5 ml may cause dizziness, so drive only if you are alert. Avoid consuming alcohol along with Religrast 300mcg Injection 0.5 ml as it could lead to increased drowsiness. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. 

Drug Interactions

Drug-Drug Interaction: Religrast 300mcg Injection 0.5 ml may have interaction with other hematopoietic agents (pegfilgrastim), medicines used to treat cancer (altretamine, bendamustine, carboplatin, busulfan, cladribine, alemtuzumab, bevacizumab, dinutuximab, gemtuzumab, procarbazine, dacarbazine. ) 

Drug-Food Interaction: Avoid alcohol consumption while taking Religrast 300mcg Injection 0.5 ml as it may increase dizziness and side effects.

Drug-Disease Interaction: Religrast 300mcg Injection 0.5 ml may cause interactions with disease conditions such as leukocytosis (high levels of white blood cells), sepsis (a life-threatening complication of an infection), glomerulonephritis (kidney impairment), thrombocytopenia (low number of platelets in the blood), have any unusual bleeding or bruising liver dysfunction, myeloid tumours (a solid composed of immature white blood cells), sickle cell disease (red blood cells to become misshapen and break down).

Drug-Drug Interactions Checker List

  • ALTRETAMINE
  • BUSULFAN
  • CLADRIBINE
  • PROCARBAZINE
  • PEGFILGRASTIM
  • DACARBAZINE
  • GEMTUZUMAB
  • DINUTUXIMAB
  • BEVACIZUMAB
  • ALEMTUZUMAB
  • CARBOPLATIN
  • BENDAMUSTINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a well-balanced and healthy diet, as it helps you to recover quickly. A dietitian will help you to create a diet plan based on your health condition. 

  • Avoid eating raw or undercooked food. 

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Limit alcohol consumption and quit smoking. 

Special Advise

  • Constantly monitors the number of blood cells in your blood, and your bone density level while you are receiving treatment with Religrast 300mcg Injection 0.5 ml.

  • Do not take any kind of immunization or vaccination without your doctor's approval while using Religrast 300mcg Injection 0.5 ml.

Disease/Condition Glossary

Neutropenia is a condition in which the number of neutrophils (a type of white blood cell) in the blood is decreased. White blood cells (neutrophils) protect the body from infections. Without enough neutrophils, the body can not fight off bacteria which increases the risk of many types of infections. It can be caused by diseases that damage the bone marrow like cancer chemotherapy, HIV or AIDS, infections or deficiencies in vitamins or minerals, such as vitamin B12, folate, or copper, and autoimmune diseases, including Crohn's disease, lupus, and rheumatoid arthritis. Severe chronic neutropenias arise from the failure of the bone marrow to produce adequate numbers of neutrophils that circulate in the blood. It appears that patients with severe chronic neutropenias are at greater risk of developing leukaemia (blood cancer) than are other people.

Country of origin

INDIA

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Other Info - REL0078

FAQs

Religrast 300mcg Injection 0.5 ml contains 'Filgrastim' is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
No, Religrast 300mcg Injection 0.5 ml is not recommended to patients with spleen disorder. It may cause your spleen to become enlarged, and it could rupture. If you experience pain in the left upper stomach/abdominal area or left shoulder, contact your doctor immediately.
If you are being treated for severe chronic neutropenia for a longer period, Religrast 300mcg Injection 0.5 ml may cause blood in your urine (haematuria). Your doctor may regularly test your urine if you experience this side effect or if a protein is found in your urine (proteinuria).
Religrast 300mcg Injection 0.5 ml should be used with caution in patients with kidney diseases. Dose adjustments may be necessary. Religrast 300mcg Injection 0.5 ml cause breathlessness (dyspnoea), tachycardia & wheeze, and even death. If you have had a history of asthma, the more possibility of these systemic allergic-like reactions. Please inform your doctor.
Religrast 300mcg Injection 0.5 ml to be taken with caution, especially if you have had heart problems. The dose may have to be adjusted by your doctor. In some cases, Religrast 300mcg Injection 0.5 ml causes inflammation of the aorta (the large blood vessel which transports blood from the heart to the body) symptoms can include fever, abdominal pain, malaise, back pain, and increased inflammatory markers. Tell your doctor if you experience those symptoms. Please inform your doctor before taking Religrast 300mcg Injection 0.5 ml.
Yes, Religrast 300mcg Injection 0.5 ml may interfere with certain lab tests such as bone imaging and blood tests (elevation in lactate dehydrogenase and alkaline phosphate), possibly causing false test results. Make sure your doctor and laboratory staff know you use Religrast 300mcg Injection 0.5 ml.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

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Alcohol

Caution

Avoid alcohol consumption while taking Religrast 300mcg Injection 0.5 ml. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

It is not known whether this Religrast 300mcg Injection 0.5 ml will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

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Breast Feeding

Caution

It is unknown whether Religrast 300mcg Injection 0.5 ml passes over into the breast milk. Please inform your doctor if you are breastfeeding before taking Religrast 300mcg Injection 0.5 ml.

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Driving

Caution

Religrast 300mcg Injection 0.5 ml may cause dizziness, drowsiness, and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

If you have liver problems, inform your doctor before receiving Religrast 300mcg Injection 0.5 ml. Your doctor may adjust the dose based on your condition or prescribe a suitable alternative.

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Kidney

Caution

Religrast 300mcg Injection 0.5 ml should be used with caution in patients with kidney diseases. Dose adjustments may be necessary. In some case, Religrast 300mcg Injection 0.5 ml cause kidney injury. Inform your doctor immediately if you experience puffiness in your face or ankles, blood in your urine, or brown-coloured urine, or you notice you urinate less than usual.

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Children

Safe if prescribed

Religrast 300mcg Injection 0.5 ml is used to treat children who are receiving chemotherapy or who suffer from severe low white blood cell count (neutropenia). The doctor will decide the dose of Religrast 300mcg Injection 0.5 ml based on the age, body weight and condition of your child.

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