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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Benz Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Remethyl PG Capsule

Remethyl PG Capsule belongs to the class of medications ‘anticonvulsants’ used in the treatment of neuropathic pain. Neuropathic pain is a chronic (long-term) progressive nerve disease that causes nerve pain due to nerve damage or the nervous system's malfunctioning. It is mostly seen in patients who had suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV.

Remethyl PG Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Pregabalin acts by decreasing the pain signals sent by a damaged nerve in the body. On the other hand, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell - neuron).

You should take this medicine as prescribed by your doctor. The common side-effects of Remethyl PG Capsule are dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Inform your doctor if any of these side effects persist.

Do not take Remethyl PG Capsule if you are allergic to ‘Pregabalin’ and ‘Methylcobalamin’ or any contents before taking Remethyl PG Capsule if you have a history of heart diseases, liver or kidney disease, alcoholism, or drug abuse.  It should not be used in children and adolescents below 18 years. Inform your doctor if you are pregnant and breastfeeding. Do not drive or operate heavy machinery as Remethyl PG Capsule may cause dizziness or drowsiness. Remethyl PG Capsule contains lactose, so inform your doctor if you have any intolerance to sugars. Do not discontinue treatment without telling your doctor. 

Uses of Remethyl PG Capsule

Neuropathic pain

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Remethyl PG Capsule is a combination of two drugs: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that affects the brain's chemicals that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels (responsible for excitatory response), thereby decreasing brain activity. This effect helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cells). Together, Remethyl PG Capsule helps in providing relief from neuropathic pain and improved nerve signal conduction.  

 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Remethyl PG Capsule

  • Dizziness
  • Drowsiness
  • Headache
  • Anorexia (loss of appetite)
  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Sore throat
  • Vision problems
  • Hot sensation (burning pain)
  • Diaphoresis (sweating)
  • Weight gain

Drug Warnings

Remethyl PG Capsule may increase the risk of heart failure in patients with heart diseases. It may cause dizziness and somnolence (sleepiness). So, it might increase the risk of accidental injury in elderly patients. Remethyl PG Capsule may also cause temporary vision problems. However, if this condition is persistent, consult your doctor immediately. Patients with diabetes who gain weight with Remethyl PG Capsule may need a change in diabetic medicines. If you notice decreased urination while taking Remethyl PG Capsule , inform your doctor as Remethyl PG Capsule may cause kidney failure in some cases. It may increase suicidal tendencies, though it is rare. You may experience convulsions after discontinuing Remethyl PG Capsule . In such cases, inform your doctor immediately.  

Drug-Drug Interactions

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Folic acidSulfadiazine
Severe
Folic acidFluorouracil
Severe

Drug-Drug Interactions

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Folic acidSulfadiazine
Severe
How does the drug interact with Remethyl PG Capsule:
Sulfadiazine may decrease the blood levels and effects of Remethyl PG Capsule.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
Folic acidFluorouracil
Severe
How does the drug interact with Remethyl PG Capsule:
Co-administration of Remethyl PG Capsule with Fluorouracil may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Fluorouracil, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
Folic acidColestyramine
Severe
How does the drug interact with Remethyl PG Capsule:
Coadministration of Remethyl PG Capsule and Cholestyramine may interfere with the absorption of Remethyl PG Capsule.

How to manage the interaction:
Although taking Cholestyramine and Remethyl PG Capsule together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
Folic acidTrimethoprim
Severe
How does the drug interact with Remethyl PG Capsule:
Trimethoprim may decrease the blood levels and effects of Remethyl PG Capsule.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
Folic acidFluorouracil
Severe
How does the drug interact with Remethyl PG Capsule:
Coadministration of Remethyl PG Capsule and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
Folic acidCarbamazepine
Severe
How does the drug interact with Remethyl PG Capsule:
Coadministration of Remethyl PG Capsule and Carbamazepine may reduce the blood levels of Remethyl PG Capsule.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
Folic acidCapecitabine
Severe
How does the drug interact with Remethyl PG Capsule:
Co-administration of Remethyl PG Capsule with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Remethyl PG Capsule and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Remethyl PG Capsule:
Coadministration of Remethyl PG Capsule with Neomycin can impair the absorption of Remethyl PG Capsule and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Remethyl PG Capsule with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminChloramphenicol
Moderate
How does the drug interact with Remethyl PG Capsule:
Coadministration of Remethyl PG Capsule with Chloramphenicol can impair absorption and increase the levels of Remethyl PG Capsule which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Remethyl PG Capsule with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

 

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Remethyl PG Capsule Substitute

Substitutes safety advice
  • Neugaba M 75 mg Capsule 15's

    by Others

    19.50per tablet
  • Pregeb M 75 Capsule 10's

    by Others

    19.62per tablet
  • Pregalin M 75 Capsule 15's

    by Others

    20.88per tablet
  • Maxgalin M 75 Capsule 15's

    by Others

    17.76per tablet
  • Pregastar M 75 Capsule 15's

    by AYUR

    21.96per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Remethyl PG Capsule is a combination of two medicines: Pregabalin and Methylcobalamin. Remethyl PG Capsule block the brain's pain signals and protect nerve cells from further damage, thereby improving nerve signal conduction to the whole body parts. These effects help to reduce pain in patients with neuropathic pain.

Remethyl PG Capsule should not be given to children and adolescents under the age of 18 years as it may increase suicidal thoughts.

Remethyl PG Capsule should not be stopped abruptly as it may cause withdrawal reactions such as trouble sleeping, headache, nausea, feeling anxious, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating, and dizziness. Remethyl PG Capsule should be stopped gradually over a minimum of 1 week.

Remethyl PG Capsule can be used in patients with diabetes if they have neuropathic pain. However, inform your doctor if you notice any weight gain while using Remethyl PG Capsule . Your doctor may change your diabetic medicines to stop weight gain. Also, take some measures to control weight such as eating a balanced diet and exercising regularly.

Remethyl PG Capsule may cause drowsiness. So, it is advised to refrain from activities such as driving or operating heavy machinery if you feel sleepy after taking Remethyl PG Capsule .

You may notice pain improvement within 2-3 days after taking Remethyl PG Capsule . However, it may take 2-3 months for your symptoms to improve depending on your health condition.

Drug-Drug Interactions Checker List

  • OXYCODONE
  • LORAZEPAM
  • OMEPRAZOLE
  • COLCHICINE
  • NEOMYCIN

Special Advise

  • Remethyl PG Capsule may increase suicidal thoughts. Extreme caution is advised with people suffering from suicidal tendencies or psychological problems.
  • Remethyl PG Capsule is known to cause dizziness and sleepiness, so it is advised to refrain from driving or doing any work that requires attention or concentration.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease, infection, or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sense is also a common symptom of neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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