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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Renophylline 25 mg Injection 10 ml

Renophylline 25 mg Injection 10 ml belongs to the class of drugs called bronchodilators. It is indicated for the relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease. Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Renophylline 25 mg Injection 10 ml contains Aminophylline, which helps to provide relief of bronchospasm associated with asthma and chronic obstructive pulmonary disease (COPD). Aminophylline relaxes and opens air passages in the lungs, thereby it making breathing easier.

Renophylline 25 mg Injection 10 ml is usually administered by a qualified healthcare professional; do not self-administer. Renophylline 25 mg Injection 10 ml may cause certain side effects, including upset stomach, stomach pain, diarrhoea, headache, restlessness, injection site reactions and irritability. Most of these side effects of Renophylline 25 mg Injection 10 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before prescribing the Renophylline 25 mg Injection 10 ml, let your doctor know about all your medical conditions, allergic reactions, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Renophylline 25 mg Injection 10 ml may cause insomnia and restlessness; therefore, avoid driving vehicles or operating machinery until you return to normal. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Renophylline 25 mg Injection 10 ml

Asthma, Chronic obstructive pulmonary disease (COPD)

Medicinal Benefits

Renophylline 25 mg Injection 10 ml contains Aminophylline. It belongs to the class of drugs called bronchodilators. It is indicated to relieve bronchospasm associated with asthma and chronic obstructive pulmonary disease. Aminophylline relaxes and opens air passages in the lungs, making breathing easier. Besides this, it relieves various symptoms such as cough, wheezing, shortness of breath, and trouble breathing by increasing airflow through the bronchial tubes.

Side Effects of Renophylline 25 mg Injection 10 ml

  • Upset stomach
  • Stomach pain
  • Diarrhea
  • Headache
  • Restlessness
  • Insomnia
  • Irritability
  • Injection site reactions

Directions for Use

Renophylline 25 mg Injection 10 ml will be administered by a trained healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before receiving Renophylline 25 mg Injection 10 ml, let your doctor know about all your medical conditions, such as if you have or have ever had seizures, heart disease, an overactive or underactive thyroid gland, high blood pressure, or kidney or liver disease or if you have a history of alcohol abuse, allergic reactions (especially aminophylline, theophylline’s, theobromine, caffeine or to any of the excipients present in Renophylline 25 mg Injection 10 ml), and all medication history you are using. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before receiving Renophylline 25 mg Injection 10 ml. Avoid the consumption of tobacco. Smoking may affect the effectiveness of aminophylline.

Therapeutic Class

BRONCHODILATOR

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
AminophyllineFluvoxamine
Severe

Drug-Drug Interactions

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AminophyllineRiociguat
Critical
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Riociguat may significantly lower your blood pressure.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Riociguat can cause an interaction, however, it can be taken only if a doctor has advised it. If you experience dizziness, lightheadedness, shortness of breath, fainting, flushing, headache, and nasal congestion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineFluvoxamine
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Fluvoxamine may significantly increases the blood levels of Renophylline 25 mg Injection 10 ml, which may lead to serious side effects.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Fluvoxamine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, difficulty breathing, or loss of appetite (less desire to eat) contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineAtenolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of atenolol with Renophylline 25 mg Injection 10 ml could certainly reduce the efficacy of atenolol and enhance the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking atenolol alongside Renophylline 25 mg Injection 10 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineLabetalol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Combination of Renophylline 25 mg Injection 10 ml with Labetalol can make labetalol less effective and increase the side effects of Renophylline 25 mg Injection 10 ml which can be serious.

How to manage the interaction:
Although taking Labetalol and Renophylline 25 mg Injection 10 ml together can result in an interaction, it can be taken only if a doctor has advised it. However, if you experience irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineEnoxacin
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Enoxacin together could increase the levels and enhance the effects of Renophylline 25 mg Injection 10 ml leading to increased risk or severity of side effects.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with enoxacin can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, diarrhea, headache, insomnia, seizures, or heart palpitations, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineBetaxolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Taking Renophylline 25 mg Injection 10 ml and Betaxolol together may reduce the effectiveness of Betaxolol and increase the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml and Betaxolol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, tremors(shakings), restlessness, irregular heartbeats, or difficulty breathing, contact the doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllinePropranolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Propranolol together can make propranolol less effective and increase the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Propranolol can cause an interaction. However, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineTramadol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Tramadol with Renophylline 25 mg Injection 10 ml can increase the risk of cause seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml and tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as seizures, dizziness, drowsiness, or difficulty concentrating, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
AminophyllineBisoprolol
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Co-administration of Renophylline 25 mg Injection 10 ml with Bisoprolol could reduce the metabolism of Renophylline 25 mg Injection 10 ml which increased the levels and enhance the effects of Renophylline 25 mg Injection 10 ml.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml and bisoprolol together can result in an interaction; it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AminophyllineCiprofloxacin
Severe
How does the drug interact with Renophylline 25 mg Injection 10 ml:
Coadministration of Renophylline 25 mg Injection 10 ml with Ciprofloxacin together could increase the levels and enhance the effects of Renophylline 25 mg Injection 10 ml. Increased levels of Renophylline 25 mg Injection 10 ml can increase the risk or severity of side effects.

How to manage the interaction:
Taking Renophylline 25 mg Injection 10 ml with Ciprofloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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AMINOPHYLLINE-25MGPeptic ulcer, site unspecified
Severe
AMINOPHYLLINE-25MGOther disorders of kidney and ureter, not elsewhere classified
Severe

Drug-Diseases Interactions

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AMINOPHYLLINE-25MGPeptic ulcer, site unspecified
Severe
How does the disease interact with Renophylline 25 mg Injection 10 ml:
methylxanthines should be administered with extreme caution in patients with active peptic ulcer disease.

How to manage the interaction:
Renophylline 25 mg Injection 10 ml therapy is not recommended in patients with peptic ulcer disease as it stimulates acid secretion in the stomach. However, it can be taken if your doctor has advised it. If you experience symptoms such as nausea, vomting, pain or discomfort in stomach, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-25MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Renophylline 25 mg Injection 10 ml:
theophyllines should be administered cautiously in patients with impaired renal function.

How to manage the interaction:
Renophylline 25 mg Injection 10 ml therapy is not recommended in patients with kidney disease as it can get accumulated and lead to increased risk or severity of Renophylline 25 mg Injection 10 ml side effects. It can be taken if your doctor has advised it. However, if you experience any symptoms like nausea, vomiting, dizziness, fatigue, sleeplessness, irritability, headache, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-25MGConvulsions, not elsewhere classified
Severe
How does the disease interact with Renophylline 25 mg Injection 10 ml:
The use of theophylline's is contraindicated in patients with seizure disorders.

How to manage the interaction:
Renophylline 25 mg Injection 10 ml therapy is not recommended in patients with a history of seizures or head trauma as it can increase the risk or severity of seizures which can be fatal. It can be taken if your doctor has advised it. However, if you experience any symptoms like nausea, vomiting, dizziness, fatigue, sleeplessness, irritability, headache, jerking movements of arms or legs, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-25MGGastro-oesophageal reflux disease
Moderate
How does the disease interact with Renophylline 25 mg Injection 10 ml:
methylxanthines should be administered cautiously in patients with significant gastroesophageal reflux.

How to manage the interaction:
Renophylline 25 mg Injection 10 ml therapy is not recommended in patients with gastric disease as it stimulates acid secretion in the stomach. However, it can be taken if your doctor has advised it. If you experience symptoms such as nausea, vomting, pain or discomfort in stomach, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-25MGCare involving dialysis
Moderate
How does the disease interact with Renophylline 25 mg Injection 10 ml:
Theophylline is removed by hemodialysis. Doses should either be scheduled for administration after dialysis or supplemental doses be given after dialysis.

How to manage the interaction:
Patients receiving dialysis are not advised to use Renophylline 25 mg Injection 10 ml because it can be eliminated during the procedure. Dialysis should be secluded before taking the Renophylline 25 mg Injection 10 ml dose. Do not discontinue any medications without first consulting your doctor.
AMINOPHYLLINE-25MGOther cardiac arrhythmias
Moderate
How does the disease interact with Renophylline 25 mg Injection 10 ml:
theophyllines should be administered caution in patients with tachyarrhythmias.

How to manage the interaction:
Renophylline 25 mg Injection 10 ml therapy is not recommended in patients with a risk of cardiac diseases, or high or low blood pressure, as this can increase the possibility or severity of side effects.

Drug-Drug Interactions Checker List

  • CIMETIDINE
  • ERYTHROMYCIN
  • CIPROFLOXACIN
  • FLUCONAZOLE
  • ALLOPURINOL
  • DILTIAZEM
  • PROPRANOLOL
  • FLUVOXAMINE
  • PHENYTOIN
  • CARBAMAZEPINE
  • FUROSEMIDE

Diet & Lifestyle Advise

  • Eat a healthy diet specially green leafy vegetables, and strictly do not consume alcohol or caffeine (coffee, tea and cola drinks and chocolate).
  • Drink plenty of fluids daily to thin mucus, making it easier to cough out.
  • Smoking should be avoided while receiving Renophylline 25 mg Injection 10 ml as it can alter the blood levels of aminophylline, which may affect the dosing.
  • It is very important to maintain hygiene, like washing hands after coming from outside, as people with asthma/COPD are at a greater risk of infections.
  • Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.

Habit Forming

No

Special Advise

  • The doctor may suggest some tests to know the root cause of the respiratory disorder, such a Spirometry (check the narrowing of bronchial tubes) and Peak flow (check how difficult it is to exhale).
  • Please avoid the use of Tobacco and Marijuana as it decreases the efficacy of Renophylline 25 mg Injection 10 ml. 
  • If you have a glucose test or lipid profile test, let your doctor know about this, as prolonged use of Renophylline 25 mg Injection 10 ml may increase glucose levels and free fatty acid in the body. 

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness and cough, especially at night. The symptoms of mild persistent asthma may occur more than two times a week and up to 4 nights a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

Renophylline 25 mg Injection 10 ml Substitute

Substitutes safety advice
  • Aminolin Injection 10 ml

    by Others

    3.24per tablet
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