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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

ABCIXIMAB-10MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Reopro 10 mg Injection 5 ml

Reopro 10 mg Injection 5 ml belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Reopro 10 mg Injection 5 ml is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

Reopro 10 mg Injection 5 ml may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Reopro 10 mg Injection 5 ml should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Reopro 10 mg Injection 5 ml

Myocardial infarction (heart attack)

Directions for Use

A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. Hence, do not self-administer.

Medicinal Benefits

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Reopro 10 mg Injection 5 ml

  • Bleeding
  • Nausea
  • Headache
  • Abdominal pain
  • Hypotension
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection

Drug Warnings

Do not receive Reopro 10 mg Injection 5 ml if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug-Drug Interactions

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AbciximabIbrutinib
Severe
AbciximabProtamine
Severe

Drug-Drug Interactions

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AbciximabIbrutinib
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
When Ibrutinib and Reopro 10 mg Injection 5 ml are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Ibrutinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
AbciximabProtamine
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Coadministration of protamine and Reopro 10 mg Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Protamine with Reopro 10 mg Injection 5 ml can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
AbciximabClopidogrel
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Coadministration of Clopidogrel with Reopro 10 mg Injection 5 ml it increases the risk of bleeding.

How to manage the interaction:
Although there is a interaction between clopidogrel and Reopro 10 mg Injection 5 ml, but it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, and weakness. Do not discontinue any medications without consulting your doctor.
AbciximabDalteparin
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
The combined use of Reopro 10 mg Injection 5 ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Dalteparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as bleeding, severe bleeding, bruising, dark or black stools, severe headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
AbciximabDasatinib
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Using Dasatinib together with Reopro 10 mg Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away - bruising, feeling dizzy or lightheaded, dark stools, intense headaches. Do not stop using any medications without talking to a doctor.
AbciximabFondaparinux
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Taking Reopro 10 mg Injection 5 ml with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Reopro 10 mg Injection 5 ml and Fondaparinux, it can be taken if prescribed by a doctor. However, if you experience bleeding, bruising, feeling dizzy or lightheaded, dark or black stools, severe headache, weakness, bleeding, or vomiting contact a doctor immediately. Do not stop using any medications without a doctor's advice.
AbciximabDeferasirox
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Using deferasirox together with Reopro 10 mg Injection 5 ml may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Reopro 10 mg Injection 5 ml with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.
AbciximabDabigatran etexilate
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Taking Dabigatran etexilate with Reopro 10 mg Injection 5 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Reopro 10 mg Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
AbciximabCangrelor
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Co-administration of Reopro 10 mg Injection 5 ml with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Cangrelor with Reopro 10 mg Injection 5 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.
AbciximabNepafenac
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Using Nepafenac and Reopro 10 mg Injection 5 ml can interfere with clotting and cause bleeding, especially when used regularly or for prolonged periods.

How to manage the interaction:
Although taking Nepafenac and Reopro 10 mg Injection 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood, severe headache, and weakness call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Reopro 10 mg Injection 5 ml Substitute

Substitutes safety advice
  • Faximab 10 Injection 5 ml

    by Others

    1525.20per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • CLOPIDOGREL
  • ENOXAPARIN
  • CAPTOPRIL
  • ENALAPRIL
  • NIFEDIPINE
  • CILNIDIPINE
  • ATENOLOL
  • SOTALOL
  • WARFARIN
  • HEPARIN

Special Advise

  • Before administration of Reopro 10 mg Injection 5 ml, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
  • As Reopro 10 mg Injection 5 ml will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

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