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  3. Reopro 10 mg Injection 5 ml

Reopro 10 mg Injection 5 ml, Pack of 1 INJECTION
Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

ABCIXIMAB-10MG

Manufacturer/Marketer :

Eli Lilly and Company (India) Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Reopro 10 mg Injection 5 ml

Reopro 10 mg Injection 5 ml belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. Reopro 10 mg Injection 5 ml is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

Reopro 10 mg Injection 5 ml may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Reopro 10 mg Injection 5 ml should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of Reopro 10 mg Injection 5 ml

Myocardial infarction (heart attack)

Directions for Use

A trained healthcare professional will administer Reopro 10 mg Injection 5 ml. Hence, do not self-administer.

Medicinal Benefits

Reopro 10 mg Injection 5 ml contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. Reopro 10 mg Injection 5 ml results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Reopro 10 mg Injection 5 ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not receive Reopro 10 mg Injection 5 ml if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. Reopro 10 mg Injection 5 ml is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving Reopro 10 mg Injection 5 ml if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. Reopro 10 mg Injection 5 ml is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug-Drug Interactions

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AbciximabDabigatran etexilate
Severe
AbciximabDasatinib
Severe

Drug-Drug Interactions

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AbciximabDabigatran etexilate
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Taking Dabigatran etexilate with Reopro 10 mg Injection 5 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Reopro 10 mg Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
AbciximabDasatinib
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Using Dasatinib together with Reopro 10 mg Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away - bruising, feeling dizzy or lightheaded, dark stools, intense headaches. Do not stop using any medications without talking to a doctor.
AbciximabHeparin
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Taking Reopro 10 mg Injection 5 ml with Heparin may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Reopro 10 mg Injection 5 ml with Heparin can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AbciximabPrasugrel
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Co-administration of Reopro 10 mg Injection 5 ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Taking Prasugrel with Reopro 10 mg Injection 5 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of the following symptoms: unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
AbciximabDalteparin
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
The combined use of Reopro 10 mg Injection 5 ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Dalteparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as bleeding, severe bleeding, bruising, dark or black stools, severe headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.
AbciximabIbrutinib
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
When Ibrutinib and Reopro 10 mg Injection 5 ml are taken together, there is a chance that bleeding and haemorrhage risk or severity will rise.

How to manage the interaction:
Taking Reopro 10 mg Injection 5 ml with Ibrutinib together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness, consult a doctor. Do not discontinue any medications without a doctor's advice.
AbciximabClopidogrel
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Coadministration of Clopidogrel with Reopro 10 mg Injection 5 ml it increases the risk of bleeding.

How to manage the interaction:
Although there is a interaction between clopidogrel and Reopro 10 mg Injection 5 ml, but it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, and weakness. Do not discontinue any medications without consulting your doctor.
AbciximabFondaparinux
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Taking Reopro 10 mg Injection 5 ml with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Reopro 10 mg Injection 5 ml and Fondaparinux, it can be taken if prescribed by a doctor. However, if you experience bleeding, bruising, feeling dizzy or lightheaded, dark or black stools, severe headache, weakness, bleeding, or vomiting contact a doctor immediately. Do not stop using any medications without a doctor's advice.
AbciximabProtamine
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Coadministration of protamine and Reopro 10 mg Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Protamine with Reopro 10 mg Injection 5 ml can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
AbciximabCangrelor
Severe
How does the drug interact with Reopro 10 mg Injection 5 ml:
Co-administration of Reopro 10 mg Injection 5 ml with Cangrelor can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Cangrelor with Reopro 10 mg Injection 5 ml can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: difficulty with bleeding, complications, bruising, feeling dizzy or lightheaded, dark or sticky stools, intense headache, weakness, or bleeding or vomiting. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Managing stress with meditation, yoga, and massage.
  • Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Reopro 10 mg Injection 5 ml Substitute

Substitutes safety advice

Product Substitutes

Author Details

Lakshmithulasi YarraguntaDoctor badge

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Reopro 10 mg Injection 5 ml contains Abciximab, which works by blocking the activity of glycoprotein IIb/IIIa receptor and thereby prevents platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

Reopro 10 mg Injection 5 ml is usually administered along with heparin and aspirin, so it might increase the risk of bleeding. Inform the doctor immediately if you notice excess bleeding.

Reopro 10 mg Injection 5 ml may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • CLOPIDOGREL
  • ENOXAPARIN
  • CAPTOPRIL
  • ENALAPRIL
  • NIFEDIPINE
  • CILNIDIPINE
  • ATENOLOL
  • SOTALOL
  • WARFARIN
  • HEPARIN

Special Advise

  • Before administration of Reopro 10 mg Injection 5 ml, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
  • As Reopro 10 mg Injection 5 ml will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.

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