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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS

About Repoitin 4000IU Injection 1's

Repoitin 4000IU Injection 1's belongs to the class of medication called 'blood-forming agent'  primarily used to treat anaemia (low red blood cell count) in persons with chronic kidney disease (CKD), patients affected with HIV, and those receiving chemotherapy for cancer (except for bone marrow or blood cells' cancer). Anaemia occurs when the body has a lower amount of red blood cells or haemoglobin. In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia.

Repoitin 4000IU Injection 1's contains a human-made protein known as 'Epoetin alfa' which works by providing signals to the bone marrow to make more red blood cells (RBCs). Repoitin 4000IU Injection 1's helps to reverse anaemia and reduce the need for blood transfusion. Repoitin 4000IU Injection 1's is a biologic response modifier and erythropoiesis-stimulating protein. In chronic kidney disease, when the kidney fails to produce sufficient 'erythropoietin protein' which aids in the formation of red blood cells, Repoitin 4000IU Injection 1's stimulates the production of this protein in the bone marrow. 

Repoitin 4000IU Injection 1's will be administered by a healthcare professional; do not self-administer. The most common side effects of Repoitin 4000IU Injection 1's are shortness of breath,  cough, low blood pressure during dialysis, headache, body aches, diarrhoea, injection site pain and abdominal pain. Most of these side effects of Repoitin 4000IU Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you have uncontrolled/untreated high blood pressure or red cell aplasia (a type of anaemia) due to epoetin alfa or darbepoetin alfa, please inform your doctor before taking Repoitin 4000IU Injection 1's to avoid any complications. Inform your doctor immediately, if you feel weak, lightheaded, tired, or short of breath, or if your skin looks pale as it may be a sign that the body has stopped responding to Repoitin 4000IU Injection 1's. It is not known whether Repoitin 4000IU Injection 1's will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant and breastfeeding before starting treatment with this medicine. Repoitin 4000IU Injection 1's is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might be lost. Do not store in the freezer or the fridge.

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Repoitin 4000IU Injection 1's

Anemia in cancer, Anemia in chronic kidney disease, Anemia in HIV

Medicinal Benefits

Repoitin 4000IU Injection 1's is a human-made form of naturally occurring erythropoiesis-stimulating protein or erythropoietin (a hormone produced by the kidney's specialized cells and is responsible for protecting red blood cells against destruction and also stimulates the cells of bone marrow to produce more amount of red blood cells). Deficiency of erythropoietin happens when a person is suffering from chronic kidney diseases, which in turn causes low red blood cells count causing anemia.  This medicine is primarily indicated for treating anemia (low red blood cell count) in persons with long-term serious (chronic) kidney disease, persons receiving chemotherapy for some types of cancer except for bone marrow or blood cells cancer, and persons taking zidovudine to treat HIV(human immunodeficiency virus). Repoitin 4000IU Injection 1's is also used to reduce the need for red blood cell transfusions in adults having certain types of surgery. Repoitin 4000IU Injection 1's contains a protein 'Epoetin alfa' which works by providing signals to the bone marrow to make more red blood cells. 

Side Effects of Repoitin 4000IU Injection 1's

  • Shortness of breath Cough
  • Hypertension (high blood pressure)
  • High blood sugar
  • Headache
  • Body aches
  • Diarrhoea
  • Injection site pain 
  • Abdominal pain (stomach pain) 

Directions for Use

Repoitin 4000IU Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Repoitin 4000IU Injection 1's can enhance the risk of blood clots and serious heart problems including heart attack so tell your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding. This medicine may speed up tumor growth, or shorten remission or survival time in some people with certain types of cancer. Inform your doctor before taking Repoitin 4000IU Injection 1's if you have heart disease, high blood pressure, kidney disease, stroke, heart attack, blood clot, seizure, or latex allergy. Do not take Repoitin 4000IU Injection 1's if you are pregnant or breastfeeding unless prescribed by the doctor. Repoitin 4000IU Injection 1's should not be given to children below 1 month of age, as safety and effectiveness have not been established. Do not use Repoitin 4000IU Injection 1's from a multi-dose vial when giving medicine to a baby. The multi-dose vial contains an ingredient (benzyl alcohol) that can cause serious side effects or death in very young infants or premature babies. Repoitin 4000IU Injection 1's may affect a person's ability to drive as it may cause convulsions during the initial days of treatment, so a person taking Repoitin 4000IU Injection 1's should avoid driving or operating any machine. Avoid consuming alcohol along with Repoitin 4000IU Injection 1's as it could lead to increased dizziness and sleepiness. 

Therapeutic Class

ERYTHROPOIESIS STIMULATING AGENTS (ESAs)

Drug-Drug Interactions

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ErythropoietinPomalidomide
Severe
ErythropoietinThalidomide
Severe

Drug-Drug Interactions

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ErythropoietinPomalidomide
Severe
How does the drug interact with Repoitin 4000IU Injection 1's:
Pomalidomide can cause serious blood clots and taking it alongside Repoitin 4000IU Injection 1's may enhance the risk.

How to manage the interaction:
Co-administration of Repoitin 4000IU Injection 1's with Pomalidomide can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ErythropoietinThalidomide
Severe
How does the drug interact with Repoitin 4000IU Injection 1's:
Taking thalidomide with Repoitin 4000IU Injection 1's may increase the risk or severity of thromboembolism(a circulating blood clot that gets stuck and causes an obstruction).

How to manage the interaction:
Although taking Repoitin 4000IU Injection 1's and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ErythropoietinCarfilzomib
Severe
How does the drug interact with Repoitin 4000IU Injection 1's:
Carfilzomib can cause serious blood clots and taking it alongside Repoitin 4000IU Injection 1's may enhance the risk.

How to manage the interaction:
Co-administration of Repoitin 4000IU Injection 1's with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience chest pain, breathing difficulty, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
ErythropoietinLenalidomide
Severe
How does the drug interact with Repoitin 4000IU Injection 1's:
Combining Repoitin 4000IU Injection 1's with Lenalidomide can increase the risk of Thrombosis(formation of a blood clot ).

How to manage the interaction:
Although there is an interaction between Repoitin 4000IU Injection 1's and Lenalidomide, it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • LENALIDOMIDE
  • CYCLOSPORINE
  • CAPTOPRIL
  • ENALAPRIL
  • LISINOPRIL
  • CARFILZOMIB
  • POMALIDOMIDE
  • MOEXIPRIL

Diet & Lifestyle Advise

  • Limit the consumption of fluids, salt, potassium, phosphorous, and other electrolytes.
  • Eat a low-protein diet, and get enough calories from the foods if you are losing weight.
  • Eat foods that are high in vitamin B12, iron, and folic acid can fulfill the deficiencies of happed in kidney disease.
  • Include a little number of healthy fats in your diet that gives you enough energy to be active during the day; however, try to limit fats that make you fat. Try to include olive oil, peanut oil, and corn oil in your diet.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Special Advise

  • Certain diagnostic tests like Complete blood count (CBC) can help check the count of red blood cells.
  • Have regular hemoglobin tests to check whether there is an improvement in the level of red blood cells after taking Repoitin 4000IU Injection 1's or not.
  • You should not use Repoitin 4000IU Injection 1's if you have uncontrolled high blood pressure (hypertension), or if you have ever had pure red cell aplasia (PRCA, a type of anemia) caused by using Repoitin 4000IU Injection 1's. 
  • Call your doctor at once if you experience any sign of a blood clot, sudden numbness or weakness, blur vision, speech problem, chest pain, trouble breathing, pain or cold feeling in leg or arm. 
  • Discard any leftover medicine in a multi-dose vial of Repoitin 4000IU Injection 1's 21 days after the first use.

Author Details

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Disease/Condition Glossary

Anaemia: It occurs when the body has a lower amount of red blood cells or haemoglobin than normal haemoglobin (iron-rich protein responsible for allowing red blood cells to carry more oxygen from the lungs to the rest of the body).  In chronic kidney disease, the kidney gets damaged and doesn't filter the blood, leading to anaemia. Symptoms of anaemia in chronic kidney disease include fatigue or tiredness, shortness of breath, ashen skin, weakness, body aches, chest pain, dizziness, fainting, fast or irregular heartbeat, headache, sleep problems, and trouble concentrating. 

Repoitin 4000IU Injection 1's Substitute

Substitutes safety advice
  • WEPOX SAFE 4000IU INJECTION PFS

    1374.30per tablet
  • EPOTRUST 4000IU INJECTION 1ML

    1212.75per tablet
  • EPOTRUST 4000IU INJECTION 0.4ML

    1465.20per tablet
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