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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Composition :

SOFOSBUVIR-400MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Resof 400 Tablet

Resof 400 Tablet belongs to a class of drugs called antivirals used in the treatment of chronic hepatitis C virus (HCV) infection. Resof 400 Tablet is used in combination with other antiviral medicines. Hepatitis C is a severe liver infection caused by the hepatitis C virus (HCV). It is contagious (spreads from one person to another) and spreads through contact with the infected person’s blood.

Resof 400 Tablet contains Sofosbuvir, which lowers the amount of hepatitis C virus in the body and removes the virus from the blood over a period of time.

Take Resof 400 Tablet as prescribed. You are advised to take Resof 400 Tablet for as long as your doctor has advised it based on your medical condition. In some cases, Resof 400 Tablet may cause common side effects such as fever, chills, headache, nausea, vomiting, diarrhoea, tired and irritable, dizziness or loss of appetite. Most of these side effects of Resof 400 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Sofosbuvir or any other medicines. Avoid pregnancy during treatment with Resof 400 Tablet as it may harm the unborn baby when used in combination with ribavirin. You or your partner must use an effective birth control method during and after this treatment. However, contact your doctor immediately if you become pregnant during treatment or in the months following your treatment with Resof 400 Tablet . Drive only if you are alert, as Resof 400 Tablet may cause dizziness, tiredness, blurred vision and reduced attention.

Uses of Resof 400 Tablet

Chronic hepatitis C virus (HCV) infection

Directions for Use

Take Resof 400 Tablet as advised by your doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Resof 400 Tablet contains Sofosbuvir, an antiviral drug used to treat chronic hepatitis C virus (HCV) infection. It works by lowering the amount of hepatitis C virus in the body and removing the virus from the blood over a period of time. Thus, it helps in reducing the amount of hepatitis C virus in the body. Resof 400 Tablet is commonly used in combination with other antiviral medicines such as Ribavirin (for children and adults) and Peginterferon alfa and ribavirin (for adults).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Resof 400 Tablet

  • Fever
  • Chills
  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Feeling tired and irritable
  • Feeling dizzy
  • Loss of appetite

Drug Warnings

Please tell your doctor if you are allergic to Sofosbuvir or any other medicines. If you are currently taking rifampicin (antibiotic), carbamazepine, phenobarbital and phenytoin (anticonvulsants), or St. John’s wort (herbal medicine used to treat depression), avoid taking Resof 400 Tablet . If you are currently taking or have taken amiodarone (the medicine to treat irregular heartbeats) in the last few months, inform your doctor before taking Resof 400 Tablet as it may result in a life-threatening slow heartbeat; your doctor may prescribe alternate treatments, or if Resof 400 Tablet is prescribed, additional heart monitoring may be recommended. Avoid pregnancy during treatment with Resof 400 Tablet as it may harm the unborn baby when used in combination with ribavirin. You or your partner must use an effective birth control method during and after this treatment. However, contact your doctor immediately if you become pregnant during treatment or in the months following your treatment with Resof 400 Tablet . Drive only if you are alert, as Resof 400 Tablet may cause dizziness, tiredness, blurred vision and reduced attention. You are advised to take proper precautions if you are infected with the hepatitis C virus infection to prevent the spread of infection to others. 

Drug-Drug Interactions

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SofosbuvirCarbamazepine
Severe
SofosbuvirModafinil
Severe

Drug-Drug Interactions

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SofosbuvirCarbamazepine
Severe
How does the drug interact with Resof 400 Tablet:
Taking carbamazepine and Resof 400 Tablet together may possibly reduce the effects of Resof 400 Tablet, which may make the medication less effective.

How to manage the interaction:
Although taking carbamazepine and Resof 400 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SofosbuvirModafinil
Severe
How does the drug interact with Resof 400 Tablet:
Coadministration of Resof 400 Tablet with Modafinil may significantly reduce the blood levels of Resof 400 Tablet.

How to manage the interaction:
Co-administration of Modafinil with Resof 400 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms of stomach pain or swelling, Fatigue, Fever, Yellowing of skin or eyes, Dark urine, loss of appetite, or nausea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
SofosbuvirRifabutin
Severe
How does the drug interact with Resof 400 Tablet:
Taking Rifabutin and Resof 400 Tablet may significantly reduce the blood levels of Resof 400 Tablet, which may make the medication less effective.

How to manage the interaction:
Taking Resof 400 Tablet with Rifabutin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SofosbuvirOxcarbazepine
Severe
How does the drug interact with Resof 400 Tablet:
Oxcarbazepine can drastically lower Resof 400 Tablet levels in the blood, making the medicine less effective in treating.

How to manage the interaction:
Although taking oxcarbazepine with Resof 400 Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
SofosbuvirPhenobarbital
Severe
How does the drug interact with Resof 400 Tablet:
Phenobarbital can drastically lower Resof 400 Tablet levels in the blood, making the medicine less effective.

How to manage the interaction:
Although taking phenobarbital with Resof 400 Tablet can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without consulting a doctor.
SofosbuvirPhenytoin
Severe
How does the drug interact with Resof 400 Tablet:
Using Resof 400 Tablet together with phenytoin may significantly reduce the blood levels of Resof 400 Tablet.

How to manage the interaction:
Although there is a possible interaction between Resof 400 Tablet and Phenytoin, you can take these medicines together if prescribed by a doctor. Doctors can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include plenty of vegetables and fruits, whole grains such as brown rice, oats, quinoa and barley.
  • Eat lean protein such as skinless chicken, fish, beans and egg whites.
  • Include healthy fats like avocados, olive oil and nuts.
  • Eat low-fat or non-fat dairy products to minimise damage to the liver.
  • Drink plenty of water for better processing of food by the body.
  • Avoid sugary foods such as cake, cookies, packaged baked food or soda. Also, avoid heavy salt foods.
  • Avoid foods containing saturated fats such as fried foods, fatty cuts of meat, sour cream, butter and other high-fat dairy products, as they may lead to weight gain and result in fatty liver.
  • Avoid smoking and alcohol consumption as they may increase the risk of liver damage.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Resof 400 Tablet Substitute

Substitutes safety advice
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  • Sovihep 400mg Tablet 28's

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Resof 400 Tablet contains Sofosbuvir, which lowers the amount of hepatitis C virus in the body and removes the virus from the blood over a period of time. Thus, it helps in reducing the amount of hepatitis C virus in the body.

Hepatitis C virus infection is contagious and spreads from one person to another through contact with an infected person’s blood. Therefore, it is recommended to avoid sharing personal items or needles containing an infected person's blood.

Resof 400 Tablet should be used with caution in diabetic patients as it may cause hypoglycaemia (low blood sugar) after starting the treatment. Therefore, if you have diabetes, inform your doctor before taking Resof 400 Tablet . Your doctor may monitor you closely, check your blood sugar levels or adjust your diabetes medication after starting Resof 400 Tablet .

Drug-Drug Interactions Checker List

  • OXCARBAZEPINE
  • CARBAMAZEPINE
  • PHENYTOIN
  • PHENOBARBITAL
  • MODAFINIL
  • RIFABUTIN
  • RIFAMPICIN
  • TIPRANAVIR
  • AMIODARONE

Special Advise

  • Your doctor will recommend blood tests before, during and after your treatment with Resof 400 Tablet to decide what other medicines you should take with Resof 400 Tablet and for how long and also to confirm that your treatment has worked for you.
  • If you are using warfarin or other blood thinners, inform your doctor. Your doctor may increase the frequency of your blood tests to check how well your blood can clot.

Disease/Condition Glossary

Hepatitis C: It is a severe liver infection caused by the hepatitis C virus (HCV). It is contagious (spreads from one person to another) and spreads through contact with the infected person’s blood, sharing needles, using a razor or any other personal items or even transfer from mother to baby during birth. The symptoms may not appear immediately. Some may take between 2 to 12 weeks to appear. Few people may have mild to moderate symptoms such as dark urine, loss of appetite, fever, joint pain, or stomach discomfort. The complications of untreated chronic hepatitis C include liver cancer or liver cirrhosis (scarring).

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