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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

SEVELAMER-400MG

Manufacturer/Marketer :

Zenska Life Sciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Rimsev 400 Tablet

Rimsev 400 Tablet belongs to a group of medications called phosphate binder (which decreases the level of phosphate in the body). It is primarily used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.

Rimsev 400 Tablet contains sevelamer that works by binding phosphate in the gastrointestinal tract and decreasing absorption. It effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes.

Take Rimsev 400 Tablet exactly as directed by your doctor. The most common side effects of Rimsev 400 Tablet are vomiting, upper abdominal pain, nausea, diarrhoea, stomach ache, indigestion, and flatulence. However, if the side effects persist, contact your doctor.

The use of Rimsev 400 Tablet is restricted in persons with a known history of allergic to any of the ingredients present in this medicine, have low levels of phosphate in their blood, and have a bowel obstruction. Rimsev 400 Tablet contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Rimsev 400 Tablet . Tell your doctor if you are facing swallowing problems, motility (movement) in your stomach and bowel, being sick frequently, active inflammation of the bowel,  have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. If you are pregnant or breastfeeding, please consult your doctor before taking Rimsev 400 Tablet .

Uses of Rimsev 400 Tablet

Hyperphosphatemia (high phosphorus level in blood)

Directions for Use

Tablet: Rimsev 400 Tablet should be taken as prescribed by the doctor. Swallow it as a whole with water; do not crush, break or chew it. Dispersible Tablet: Take Rimsev 400 Tablet as prescribed by the doctor. Before taking, disperse the tablet in the prescribed amount of water, mix well and then swallow it. Do not crush, chew or swallow as a whole. Powder/granules: Firstly, shake the container and open the cap. Add the powder of the packet to a cup containing two teaspoonfuls (30 ml) of water. Mix well and make your child drink within 30 minutes. It is advised not to give more than the prescribed dose of medicine.

Key Benefits

Rimsev 400 Tablet belongs to a group of medications called phosphate binder, which works by binding phosphate in the gastrointestinal tract and decreasing its absorption. This lowers the phosphate concentration in the body. It effectively reduces excess phosphate levels in the blood, prevents the unsafe buildup of phosphate in your body, helps keep your bones strong, and decreases the risk of heart disease and strokes. Rimsev 400 Tablet controls hyperphosphataemia (high blood phosphate levels) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine) or peritoneal dialysis (where the fluid is pumped into the abdomen and an internal body membrane filters the blood), and patients with chronic kidney disease.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

You should avoid taking Rimsev 400 Tablet if you are allergic to Rimsev 400 Tablet . Speak to your doctor if you have swallowing disorders, digestive tract surgery, severe constipation, have undergone major surgery on your stomach or bowel, or have serious inflammatory bowel disease. It should be used with caution if you are pregnant or planning to become pregnant. Rimsev 400 Tablet should not be recommended for breastfeeding mothers as it passes into breast milk. Avoid alcohol consumption while taking Rimsev 400 Tablet as it might cause unpleasant side effects. The safety and effectiveness of children under six years of age have not been established, so a Rimsev 400 Tablet should not be given to them. Rimsev 400 Tablet contains lactose (milk sugar). If you have an intolerance to some sugars, contact your doctor before taking Rimsev 400 Tablet . Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is advised while taking Rimsev 400 Tablet .

Diet & Lifestyle Advise

  • Take fresh fruits, vegetables, rice, milk, un-enriched corn and rice cereals, and soda without phosphate additives in your regular diet.
  • Avoid or limit high phosphorus addictive foods (processed meats, instant puddings, sauces, spreadable cheeses, and beverage products).
  •  Avoid intake of alcoholic beverages with Rimsev 400 Tablet as it can make you dehydrated and may increase the side effects. 
  • Make sure you drink plenty of fluids. This will help you clear out the extra phosphate and will help you overcome some.
  • Rimsev 400 Tablet is preferably taken with meals as it can bind to dietary phosphate and prevent its absorption into the bloodstream. Drink it with a full glass of water.
  • Do not stop taking the Rimsev 400 Tablet dose until your doctor says so.
  • Do not use Rimsev 400 Tablet if you have a history of bowel obstruction.

Side Effects of Rimsev 400 Tablet

  • Headache
  • Diarrhoea
  • Stomach upset
  • Constipation

Habit Forming

No

Therapeutic Class

[HYPOPHOSPHATEMIC AGENT]

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Author Details

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FAQs

Drug-Drug Interactions Checker List

  • CIPROFLOXACIN
  • MYCOPHENOLATE SODIUM
  • LEVOTHYROXINE SODIUM
  • ERDAFITINIB

Special Advise

  • Regular monitoring of serum phosphate levels, vitamin D, A, E, K, and folic acid is recommended while taking Rimsev 400 Tablet .

Disease/Condition Glossary

Hyperphosphatemia: Hyperphosphatemia is defined as an increased phosphate level in the blood. This condition is often a complication of chronic kidney disease. Phosphate is an important electrolyte. It strengthens your bones and teeth and produces energy.  When phosphate levels increase in the blood due to kidney impairment (the kidney does not remove extra phosphate out of the body), this can cause muscle problems and increase the risk of weak bones, heart attacks, and strokes. It is more common in people with chronic kidney disease and people on dialysis. Symptoms may include itchy skin, red eyes, bone pain, and fractures.

Have a query?

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Alcohol

Safe if prescribed

You are recommended to avoid alcohol consumption while taking Rimsev 400 Tablet to avoid unpleasant side effects.

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Pregnancy

Consult your doctor

Rimsev 400 Tablet is Category C pregnancy medicine. Please consult your doctor if you have any concerns; your doctor will prescribe you Rimsev 400 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

The safety of Rimsev 400 Tablet has not been established in breastfeeding women. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether the Rimsev 400 Tablet can be given to breastfeeding mothers or not.

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Driving

Safe if prescribed

Rimsev 400 Tablet has no or negligible influence on the ability to drive or operate any machinery.

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Liver

Consult your doctor

Rimsev 400 Tablet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed. Rimsev 400 Tablet should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

For children, SEVELAMER is available in pouches for oral suspension. Please consult your paediatrician for further information. The paediatrician will decide the dose of this medicine.

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