RISOFOS 150MG TABLET belongs to the class of medicines called bisphosphonates used to treat or prevent osteoporosis (weak and brittle bones) caused by menopause or taking steroids for a long time. Also, RISOFOS 150MG TABLET is used to treat Paget’s disease of bone. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women.  As the density of bones decreases, they weaken and are more likely to break.

RISOFOS 150MG TABLET contains Risedronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

Take RISOFOS 150MG TABLET as prescribed by your doctor. You are advised to take RISOFOS 150MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience headache, nausea, indigestion, stomach pain, cramps or discomfort, constipation, diarrhea, pain in the muscles, joints, or bones, feeling of fullness or bloating. Most of these side effects of RISOFOS 150MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to RISOFOS 150MG TABLET, any sugars, or any other medicines, please tell your doctor. Avoid taking RISOFOS 150MG TABLET if you are pregnant or breastfeeding and consult a doctor. RISOFOS 150MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking RISOFOS 150MG TABLET if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Avoid drinking alcohol as heavy drinking may also cause bone loss. Avoid smoking as it may decrease bone mineral density and increase the risk of fractures. RISOFOS 150MG TABLET may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

Risedronate (risedronate sodium) helps your bones stay as strong as possible. RISOFOS 150MG TABLET is used to treat osteoporosis and Paget’s disease. In osteoporosis, risedronate slows down the cells that break down bone. This maintains bone density and makes your bones stronger and less likely to break. In Paget's disease of bone, risedronate reduces the abnormal bone turnover that this condition causes. This helps to reduce deformity and pain and makes your bones stronger and less likely to break.

• Headache
• Nausea
• Indigestion
• Stomach pain, cramps or discomfort
• Constipation
• Diarrhoea
• Pain in the muscles, joints or bones
• Feeling of fullness
• Bloating

If you are allergic to RISOFOS 150MG TABLET,  or any other medicines, please tell your doctor. Avoid taking RISOFOS 150MG TABLET if you are pregnant or breastfeeding and consult a doctor. RISOFOS 150MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking RISOFOS 150MG TABLET if you have hypocalcaemia (low calcium levels in the blood) and severe kidney problems. Avoid drinking alcohol as heavy drinking may also cause bone loss. If you have parathyroid hormone abnormalities, lack of vitamin D, swelling, numbness or pain in the jaw, loose tooth, heavy jaw feeling or had  Barrett’s oesophagus (abnormal change in the cells lining the lower oesophagus), inform your doctor before taking RISOFOS 150MG TABLET. Avoid smoking as it may decrease bone mineral density and increase the risk of fractures. RISOFOS 150MG TABLET may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. Your doctor may prescribe calcium and vitamin D supplements if you do not take sufficient from your diet.

Drug-Drug Interaction: RISOFOS 150MG TABLET may interact with antacids (magnesium hydroxide, aluminium hydroxide), iron and calcium supplements.

Drug-Food Interaction: Avoid taking RISOFOS 150MG TABLET with milk as it contains calcium and may reduce the effectiveness of RISOFOS 150MG TABLET.

Drug-Disease Interaction: Avoid taking RISOFOS 150MG TABLET if you have hypocalcaemia (low calcium levels in the blood) and severe kidney problems. If you have parathyroid hormone abnormalities, lack of vitamin D, swelling, numbness or pain in the jaw, loose tooth, heavy jaw feeling or had  Barrett’s oesophagus (abnormal change in the cells lining the lower oesophagus), inform your doctor before taking RISOFOS 150MG TABLET.

• CALCIUM
• IRON
• MAGNESIUM HYDROXIDE
• ALUMINIUM HYDROXIDE

• Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.
• Eat daily a serving of broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables.
• Snack on calcium-rich nuts like Brazil nuts or almonds.
• Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
• Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
• Replace the meat with tofu or tempeh for extra calcium in your food.

You are advised to inform your dentist that you are taking RISOFOS 150MG TABLET before undergoing any dental surgery.

Osteoporosis: It is a bone disease that weakens and thins bones by decreasing bone density.  As the density of bones decreases, they weaken and are more likely to break. Post-menopausal women are more likely to develop osteoporosis than men because, at menopause, women’s ovaries stop producing oestrogen (a female hormone) that is essential to keep bones healthy. Following menopause, bone loss occurs, making bones weak and more likely to break. Also, long term use of steroids may affect bone strength and cause osteoporosis in both men and women. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, a bone that breaks much more easily than expected.

Paget’s bone disease: In Paget’s disease, bone remodelling (removal of old bone and replacement with new bone material) is too quick, and new bone is formed in a disordered manner making it weaker than normal. If left untreated, the bone may become deformed, painful and break.