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  3. RISPERDAL CONSTA 37.5MG INJECTION

RISPERDAL CONSTA 37.5MG INJECTION, Pack of 1 Injection
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Composition :

RISPERIDONE-37.5MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About RISPERDAL CONSTA 37.5MG INJECTION

RISPERDAL CONSTA 37.5MG INJECTION belongs to the group of medicines called 'atypical antipsychotics' used to treat schizophrenia. It is also used alone or in combination with other medicines to treat bipolar disorder. Schizophrenia is a mental disorder which causes unusual or disturbed thinking, inappropriate emotions and loss of interest in life. 

RISPERDAL CONSTA 37.5MG INJECTION contains 'Risperidone' that works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin), thereby helps in improving mood, behaviour and thoughts. 

RISPERDAL CONSTA 37.5MG INJECTION will be administered by a healthcare professional; In some cases, RISPERDAL CONSTA 37.5MG INJECTION may cause common side-effects such as headache, dizziness, drowsiness, fatigue, constipation, weight gain, and dry mouth. You are advised to talk to your doctor if you experience these side-effects persistently.

Avoid breastfeeding while on treatment with RISPERDAL CONSTA 37.5MG INJECTION. Consult your doctor if you are pregnant or planning for pregnancy. Avoid driving or operating machinery as RISPERDAL CONSTA 37.5MG INJECTION may cause dizziness. Do not consume alcohol along with RISPERDAL CONSTA 37.5MG INJECTION as it could lead to increased dizziness. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of RISPERDAL CONSTA 37.5MG INJECTION

Schizophrenia, Bipolar disorder

Directions for Use

RISPERDAL CONSTA 37.5MG INJECTION will be administered by a qualified healthcare professional; do not self-administer.

Medicinal Benefits

RISPERDAL CONSTA 37.5MG INJECTION belongs to the group of medicines called antipsychotics used to treat schizophrenia. It is also used alone or in combination with other medicines to treat bipolar disorder. RISPERDAL CONSTA 37.5MG INJECTION works by blocking the effects of chemical messengers in the brain (i.e. dopamine and serotonin), thereby helps in improving mood, behaviour, and thoughts.

Storage

Store in a cool and dry place away from sunlight
Side effects of Risperdal Consta 37.5mg Injection
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Drug Warnings

Do not take RISPERDAL CONSTA 37.5MG INJECTION if you are allergic to any of its contents. Inform your doctor if you have diabetes, high blood pressure, heart problems, low white blood cell count, seizures, breast cancer, low bone mineral density, Parkinson's disease, dehydration, phenylketonuria (accumulation of amino acid-phenylalanine in the body), liver or kidney problems. Rise slowly from sitting or lying position as RISPERDAL CONSTA 37.5MG INJECTION may cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). Consult your doctor if you are pregnant or planning for pregnancy. Avoid breastfeeding while on treatment with RISPERDAL CONSTA 37.5MG INJECTION and for at least 12 weeks after the last dose. 

Drug-Drug Interactions

verifiedApollotooltip
RisperidonePramipexole
Critical
RisperidoneSparfloxacin
Critical

Drug-Drug Interactions

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RisperidonePramipexole
Critical
How does the drug interact with Risperdal Consta 37.5mg Injection:
Taking Risperdal Consta 37.5mg Injection with Pramipexole may reduce the effectiveness of Pramipexole.

How to manage the interaction:
Taking Risperdal Consta 37.5mg Injection with Pramipexole is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneSparfloxacin
Critical
How does the drug interact with Risperdal Consta 37.5mg Injection:
Coadministration of Risperdal Consta 37.5mg Injection with sparfloxacin can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Sparfloxacin with Risperdal Consta 37.5mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneMetoclopramide
Critical
How does the drug interact with Risperdal Consta 37.5mg Injection:
Co-administration of Metoclopramide with Risperdal Consta 37.5mg Injection can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Risperdal Consta 37.5mg Injection with Metoclopramide is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, shaking, jitteriness, restlessness, pacing, and foot tapping contact a doctor immediately. Do not stop using any medications without a doctor’s advice.
RisperidoneCisapride
Critical
How does the drug interact with Risperdal Consta 37.5mg Injection:
When Risperdal Consta 37.5mg Injection is taken with Cisapride, it can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking cisapride together with Risperdal Consta 37.5mg Injection is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
RisperidoneZiprasidone
Critical
How does the drug interact with Risperdal Consta 37.5mg Injection:
Co-administration of Risperdal Consta 37.5mg Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Risperdal Consta 37.5mg Injection with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RisperidoneChloroquine
Severe
How does the drug interact with Risperdal Consta 37.5mg Injection:
Taking chloroquine with Risperdal Consta 37.5mg Injection together can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking chloroquine and Risperdal Consta 37.5mg Injection together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidoneArsenic trioxide
Severe
How does the drug interact with Risperdal Consta 37.5mg Injection:
Taking arsenic trioxide with Risperdal Consta 37.5mg Injection can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Risperdal Consta 37.5mg Injection with Arsenic trioxide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.
RisperidoneTetrabenazine
Severe
How does the drug interact with Risperdal Consta 37.5mg Injection:
Co-administration of Tetrabenazine and Risperdal Consta 37.5mg Injection can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Taking Tetrabenazine and Risperdal Consta 37.5mg Injection together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like muscle spasms or movements that you can't stop or control, such as dizziness, palpitations, drowsiness, lip smacking, chewing, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, restlessness, and foot tapping, fever, heat intolerance, excessive sweating, stiffness, difficulty moving or swallowing, sudden dizziness, lightheadedness, fainting, and fast or pounding heartbeats, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RisperidonePhenobarbital
Severe
How does the drug interact with Risperdal Consta 37.5mg Injection:
Taking Risperdal Consta 37.5mg Injection with phenobarbital may significantly reduce the blood levels of Risperdal Consta 37.5mg Injection.

How to manage the interaction:
Although taking phenobarbital and Risperdal Consta 37.5mg Injection together can possibly result in an interaction, but can be taken if your doctor has prescribed it. In case you experience any unusual side effects, consult a doctor.Do not stop using any medications without a doctor's advice.
RisperidoneNilotinib
Severe
How does the drug interact with Risperdal Consta 37.5mg Injection:
Taking Risperdal Consta 37.5mg Injection and Nilotinib can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although there is a possible interaction between Nilotinib and Risperdal Consta 37.5mg Injection, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor's treatment plan.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

RISPERDAL CONSTA 37.5MG INJECTION works by balancing the chemical messengers called neurotransmitters and blocking the effect of dopamine and serotonin located in the brain, thereby helping to improve mood, behaviour, and thoughts.

Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

RISPERDAL CONSTA 37.5MG INJECTION may cause weight gain. Therefore, avoid excessive eating and follow a healthy diet. Consult your doctor if you have any concerns.

RISPERDAL CONSTA 37.5MG INJECTION may impair fertility in females of reproductive potential due to an increase in serum prolactin levels. However, this effect may be reversible. Consult your doctor if you have any concerns.

Orthostatic hypotension could be a side-effect of RISPERDAL CONSTA 37.5MG INJECTION. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LORAZEPAM
  • DULOXETINE
  • FLUOXETINE
  • ESCITALOPRAM
  • DIVALPROEX SODIUM
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • LITHIUM
  • QUETIAPINE

Special Advise

  • If you are due to undergo surgery or dental procedure, inform the doctor that you are taking RISPERDAL CONSTA 37.5MG INJECTION.
  • Consult your doctor immediately if you have suicidal tendencies, such as thoughts of harming or killing yourself.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganized thinking, loss of interest, lack of emotions, etc.

Bipolar disorder (manic depression): Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. Symptoms of manic episodes include high energy, loss of touch with reality, and reduced need for sleep. Symptoms of depressive episodes include low motivation, low energy, and loss of interest in daily life.

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