ROFUM 500MG TABLET is a respiratory medicine that belongs to the class of 'phosphodiesterase inhibitors' primarily used to manage chronic obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease is a group of progressive lung diseases. It is a long-term condition which makes you hard to take breathe. People with COPD have emphysema and chronic bronchitis. Emphysema destroys air sacs in the lungs, which interferes with the movement of outward airflow. Bronchitis allows mucus to build up in the bronchial tubes by causing inflammation and narrowing of the tubes.

ROFUM 500MG TABLET contains Roflumilast, which helps in the treatment of chronic obstructive pulmonary disease (COPD). Roflumilast works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, Roflumilast also helps treat the symptoms. It is generally a long-term treatment.

Take ROFUM 500MG TABLET with or without food or as directed by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. You may experience diarrhoea, nausea, stomach ache, weight decrease and headache in some cases. Most of these side effects of ROFUM 500MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own. Do not stop taking ROFUM 500MG TABLET despite symptomatic relief. Treat your condition effectually, continue taking ROFUM 500MG TABLET for as long as it has been prescribed for you. Do not take this medicine if you have any moderate or severe liver problems. Consult your doctor before taking ROFUM 500MG TABLET if you are a pregnant or breastfeeding woman. Avoid consuming alcohol along with ROFUM 500MG TABLET. ROFUM 500MG TABLET is not recommended for use in children and adolescents under 18 years of age.

ROFUM 500MG TABLET contains Roflumilast, which helps in the treatment of chronic obstructive pulmonary disease (COPD). Roflumilast works by relaxing the airway in the lungs and making it easier to breathe. In addition to this, roflumilast also helps treat the symptoms. It is generally a long-term treatment.

• Diarrhoea
• Nausea
• Stomach ache
• Weight loss
• Headache
• Loss of appetite

Do not use ROFUM 500MG TABLET in more than the prescribed doses, leading to severe heart or lung problems. After taking ROFUM 500MG TABLET, if you experience irregular heartbeats, leg cramps, muscle weakness, numbness or tingling, or suicidal thinking and behaviour, please consult a doctor immediately. If you have cancer, heart disease, depression, inform your doctor before taking ROFUM 500MG TABLET.  This medicine is recommended for use in children and adolescents under 18 years of age. Before taking ROFUM 500MG TABLET, inform your doctor if you are already on medications like theophylline, oral corticosteroids, methotrexate, enoxacin or cimetidine.

Drug-Drug Interactions: ROFUM 500MG TABLET interacts with medicine used to treat allergic disorders (methylprednisolone), a drug used to treat asthma (budesonide/formoterol), drugs used to treat seizures (carbamazepine, phenytoin)

Drug-Food Interactions: Avoid alcohol consumption while taking ROFUM 500MG TABLET as it could lead to increased dizziness.

Drug-Disease Interactions: ROFUM 500MG TABLET should be taken with caution if you have a hepatic impairment, depression and weight loss.

• METHYLPREDNISOLONE
• BUDESONIDE+FORMOTEROL

• Smoking should be avoided while taking ROFUM 500MG TABLET as it can alter the blood levels of roflumilast, which may affect the dosing.
• It is essential to maintain hygiene like washing hands after coming from outside, as people with asthma/COPD are at a greater risk of infections.
• Stay active and do regular exercise to improve quality of life and increase tolerance to shortness of breath.
• Shortness of breath can be eased by doing pursed-lip breathing exercises. In this, relax your neck and shoulder muscles, breathe in with your nose for two seconds and breathe out through pursed lips for four seconds. Such exercises will help you to improve your breath.
• Eat foods rich in potassium such as tomatoes, bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.
• Drink plenty of fluids every day to thin mucus which makes it easier to cough out.
• Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas and potatoes with skin.
• Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda and energy drinks.
• Eat protein-rich foods such as meat, fish (particularly salmon, sardines, and mackerel), eggs and poultry.
• Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
• Stop smoking as it can reduce the efficacy of the ROFUM 500MG TABLET and irritate the lungs and make breathing problems worse.

• Check your weight regularly while taking this medication. Tell your doctor right away of any unusual or extreme weight loss.
• ROFUM 500MG TABLET is not a bronchodilator and is not indicated for the relief of acute bronchospasm. Always carry a rescue inhaler.

COPD: It is a group of progressive lung diseases, most commonly emphysema (shortness of breath) and chronic bronchitis (inflammation and irritation of bronchial tubes). Initially, it may be mild, but it can lead to total blockage of airways and damage the lungs in severe cases. The major cause of COPD is smoking tobacco and exposure to air pollutants like asbestos and chemicals/fumes. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).