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Composition :

EVEROLIMUS-5MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rolimus 5 Tablet

Rolimus 5 Tablet belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

Rolimus 5 Tablet contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take Rolimus 5 Tablet as prescribed by your doctor. You are advised to take Rolimus 5 Tablet for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of Rolimus 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking Rolimus 5 Tablet for as long as your doctor has prescribed. If you are known to be allergic to Rolimus 5 Tablet or any other medicines, please tell your doctor. Do not take Rolimus 5 Tablet if you are pregnant or planning for pregnancy as Rolimus 5 Tablet may harm the unborn baby. Rolimus 5 Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Rolimus 5 Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of Rolimus 5 Tablet

Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

Take Rolimus 5 Tablet with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rolimus 5 Tablet is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. Rolimus 5 Tablet travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rolimus 5 Tablet

  • Tiredness
  • Breathlessness
  • Dizziness
  • Headache
  • Loss of appetite
  • Infection
  • Mouth ulcers 
  • Sinus inflammation
  • Cough
  • Diarrhea
  • Fever
  • High level of sugar in the blood (hyperglycemia)
  • Signs of low level of red blood cells (anemia) 
  • Otitis media (infection of the ear)
  • Stomatitis (Inflammation of the mouth)
  • Upper respiratory tract infection.
  • Swelling of arms, hands, feet, and ankles

Drug Warnings

If you are known to be allergic to Rolimus 5 Tablet or any other medicines, please tell your doctor. Rolimus 5 Tablet should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take Rolimus 5 Tablet if you have recent surgery, infection and hepatitis B. Rolimus 5 Tablet may weaken your immune system, inform your doctor before taking Rolimus 5 Tablet. Rolimus 5 Tablet may also impair your kidney function. Therefore, monitor your kidney function regularly while taking Rolimus 5 Tablet. Rolimus 5 Tablet may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your Rolimus 5 Tablet. Rolimus 5 Tablet may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take Rolimus 5 Tablet if you are pregnant or planning for pregnancy as Rolimus 5 Tablet may harm the unborn baby. Rolimus 5 Tablet should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. Rolimus 5 Tablet causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusFingolimod
Severe
EverolimusPhenytoin
Severe

Drug-Drug Interactions

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EverolimusFingolimod
Severe
How does the drug interact with Rolimus 5 Tablet:
When Rolimus 5 Tablet is used with Fingolimod, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Rolimus 5 Tablet and Fingolimod, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusPhenytoin
Severe
How does the drug interact with Rolimus 5 Tablet:
Coadministration of Phenytoin and Rolimus 5 Tablet may decrease the blood levels of Rolimus 5 Tablet, which may make Rolimus 5 Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Rolimus 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
EverolimusEnzalutamide
Severe
How does the drug interact with Rolimus 5 Tablet:
Taking Enzalutamide with Rolimus 5 Tablet may decrease the blood levels of Rolimus 5 Tablet, which may make Rolimus 5 Tablet less effective in treating the condition.

How to manage the interaction:
Although taking Enzalutamide and Rolimus 5 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EverolimusAdalimumab
Severe
How does the drug interact with Rolimus 5 Tablet:
When Rolimus 5 Tablet is used with Adalimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Rolimus 5 Tablet with Adalimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusPolymyxin b
Severe
How does the drug interact with Rolimus 5 Tablet:
Taking Rolimus 5 Tablet and Polymyxin b together may increase the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Rolimus 5 Tablet and Polymyxin b, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
EverolimusGolimumab
Severe
How does the drug interact with Rolimus 5 Tablet:
When Rolimus 5 Tablet is used with Golimumab, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Rolimus 5 Tablet and Golimumab, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusBaricitinib
Severe
How does the drug interact with Rolimus 5 Tablet:
Coadministration of baricitinib and Rolimus 5 Tablet can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Rolimus 5 Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
EverolimusTeriflunomide
Severe
How does the drug interact with Rolimus 5 Tablet:
When Rolimus 5 Tablet is used with teriflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Rolimus 5 Tablet and Teriflunomide, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusGentamicin
Severe
How does the drug interact with Rolimus 5 Tablet:
Rolimus 5 Tablet may cause kidney problems, and combining it with gentamicin may increase that risk.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Rolimus 5 Tablet if prescribed by the doctor. Consult the doctor if you experience symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
EverolimusIopamidol
Severe
How does the drug interact with Rolimus 5 Tablet:
Injections of iopamidol and related contrast agents can occasionally cause kidney damage and mixing it with Rolimus 5 Tablet, may enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Rolimus 5 Tablet and Iopamidol, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUS-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Rolimus 5 Tablet with grapefruit juice can raise blood levels and enhance the effects of Rolimus 5 Tablet. Since the co-administration of Rolimus 5 Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Rolimus 5 Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Rolimus 5 Tablet Substitute

Substitutes safety advice
  • Evermil 5 Tablet 10's

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    463.30per tablet
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  • Everbliss 5 Tablet 10's

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    594.80per tablet
  • Afinitor 5 mg Tablet 10's

    by Others

    930.72per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rolimus 5 Tablet is an anticancer medicine. It belongs to a group of medicines known as a kinase inhibitor. It works by lowering the blood supply to the tumor, which reduces the growth and spread of cancer cells.

There is no specific duration of treatment with Rolimus 5 Tablet. Rolimus 5 Tablet is continued till benefit is seen or undesirable toxicity or side effects occur.

You should prevent grapefruit or grapefruit juice while taking Rolimus 5 Tablet. This is because taking them together may rise the levels of Rolimus 5 Tablet in your blood to toxic levels. Avoid the use of live vaccinations and any probable contact with people who have received live vaccinations.

Rolimus 5 Tablet can lead to serious side effects that consist of severe allergic reactions, angioedema (painless swelling under the skin) and kidney failure which can be dangerous and can lead to death. It is possible that you may develop an infection or problems associated to lungs like breathing problems.

It usually takes three to six months for most types of lung cancer to double their size. It will take a long time for lung cancer to reach a size that could be diagnosed in X-Ray.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • RITONAVIR
  • EFAVIRENZ
  • RAMIPRIL
  • VERAPAMIL
  • DILTIAZEM
  • DRONEDARONE
  • IMATINIB
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • FLUCONAZOLE

Special Advise

  • Rolimus 5 Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Rolimus 5 Tablet.
  • Do not have immunizations/vaccinations without a doctor's advice.
  • Avoid contact with people who have recently received live vaccines.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells that are stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumor cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. 

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of lung cancer is a cough that does not go easily followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices. Juices are produced by the pancreas ( a gland present behind your stomach) help in the breakdown of food and hormones which help in controlling blood sugar levels.

Kidney cancer: Kidneys are the organs on either side of your backbone directly above your waist. The tubes present inside clean and filter your blood, taking out waste foods and making urine. Kidney cancer produces in the lining of tiny tubes inside your kidneys.

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