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  3. ROPIN 0.75% INJECTION 4ML

ROPIN 0.75% INJECTION 4ML, Pack of 1
ROPIN 0.75% INJECTION 4ML, Pack of 1
ROPIN 0.75% INJECTION 4ML, Pack of 1
Not for online sale
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Lakshmithulasi Yarragunta , Pharm-D (PB)
Non returnable*
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Whats That

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Synonym :

ROPIVACAINE

Composition :

ROPIVACAINE HYDROCHLORIDE-0.75%W/V

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About ROPIN 0.75% INJECTION 4ML

ROPIN 0.75% INJECTION 4ML belongs to the class of local anaesthetic medications. It is indicated in adults for producing local or regional anaesthesia for surgery and acute pain management. Anesthesia is a medical procedure that prevents pain and discomfort during surgical or medical procedures. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. The tolerance level of pain might vary from person to person.

ROPIN 0.75% INJECTION 4ML contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION 4ML is administered only in a hospital setting by an anaesthetist. It may occasionally cause undesirable effects during the medical procedure like hypotension, nausea, vomiting, bradycardia (slow heart rate), fever, pain, postoperative complications, anaemia, paresthesia (Pins and needles), headache, pruritus (itching), and back pain. Any problems that arise during your procedure will be promptly addressed by your anaesthetist.

ROPIN 0.75% INJECTION 4ML is recommended not to use if you are hypersensitive to Ropivacaine Hydrochloride or other similar anaesthetics. So, before taking ROPIN 0.75% INJECTION 4ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Also, let your doctor know if you are pregnant or breastfeeding. The safety and efficacy of ropivacaine in pediatric patients have not been established. Patients should not drive or operate heavy machinery for at least 24 hours after receiving Ropivacaine Hydrochloride.

Uses of ROPIN 0.75% INJECTION 4ML

Surgical Anesthesia, Acute Pain Management.

Directions for Use

ROPIN 0.75% INJECTION 4ML is administered only in a hospital setting by an anaesthetist before a medical procedure.

Medicinal Benefits

ROPIN 0.75% INJECTION 4ML contains Ropivacaine Hydrochloride, which belongs to the anaesthetics class used for surgical anaesthesia. It is indicated in adults to produce local or regional anaesthesia for surgery and acute pain management. It works by blocking the transmission of pain signals from the nerves to the brain. This helps to decrease the sensation of pain.

Storage

Store in a cool and dry place away from sunlight
Side effects of Ropin 0.75% Injection 4ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug Warnings

ROPIN 0.75% INJECTION 4ML is not recommended in individuals with known hypersensitivity to ropivacaine or other amide-type local anaesthetic medication. So, tell your doctor about your medical conditions, sensitivities, and prescriptions. Inform your doctor if you are pregnant or breastfeeding. Ropivacaine's safety and efficacy in pediatric patients have not been established. After receiving Ropivacaine Hydrochloride, patients should not drive or operate heavy machinery for at least 24 hours. ROPIN 0.75% INJECTION 4ML may cause cardiac arrhythmia or cardiac arrest in some patients. Hence, careful monitoring is recommended during the treatment.

Drug-Drug Interactions

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RopivacaineNitroprusside
Severe
RopivacaineHydroxycarbamide
Severe

Drug-Drug Interactions

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RopivacaineNitroprusside
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Co-administration of Ropin 0.75% Injection 4ml and Nitroprusside can rarely cause methemoglobinemia(a rare condition that can reduce oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Ropin 0.75% Injection 4ml and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, contact your doctor immediately if you experience any symptoms like discoloration of the skin, nausea, headache, dizziness, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting your doctor.
RopivacaineHydroxycarbamide
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Ropin 0.75% Injection 4ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Ropin 0.75% Injection 4ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RopivacaineSulfasalazine
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Coadministration of Sulfasalazine with Ropin 0.75% Injection 4ml can increase the risk of methemoglobinemia, (a rare red blood cell condition where the oxygen-carrying capacity decreases).

How to manage the interaction:
Although taking Ropin 0.75% Injection 4ml and sulfasalazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
RopivacaineBupivacaine
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Combining Ropin 0.75% Injection 4ml with Bupivacaine can have additive toxic effects, so using them together increases the risk of serious side effects like methemoglobinemia (a condition that can deprive tissues and organs of oxygen), reactions in the central nervous system (e.g-convulsions, unconsciousness, coma, respiratory arrest), and cardiovascular disorders (e.g- low blood pressure, heart block, irregular heart rhythm).

How to manage the interaction:
Although there is a possible interaction between Ropin 0.75% Injection 4ml and Bupivacaine, you can take these medicines together if prescribed by a doctor. However, if you experience pale, grey, or blue-coloured skin, headache, rapid heart rate, shortness of breath, lightheadedness, or fatigue, consult a doctor. Do not stop using any medications without consulting a doctor.
RopivacaineGlyceryl trinitrate
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Coadministration of Ropin 0.75% Injection 4ml and glyceryl trinitrate has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Ropin 0.75% Injection 4ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
RopivacainePhenytoin
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Coadministration of Phenytoin with Ropin 0.75% Injection 4ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Ropin 0.75% Injection 4ml and Phenytoin together can cause an interaction, it can be taken if your doctor has suggested it. Consult a doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
RopivacaineNitrofurantoin
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Combining Nitrofurantoin with Ropin 0.75% Injection 4ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Nitrofurantoin and Ropin 0.75% Injection 4ml, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include gray discoloration of the skin, feeling sick, having a headache, feeling dizzy or lightheaded, feeling tired, having trouble breathing, a fast or irregular heartbeat, and feeling anxious or confused. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
RopivacaineMetoclopramide
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Coadministration of Ropin 0.75% Injection 4ml with metoclopramide may increase the risk of methemoglobinemia, (red blood cells unable to carry oxygen to the tissues).

How to manage the interaction:
Although there is a possible interaction between metoclopramide and Ropin 0.75% Injection 4ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as grey discolouration of the skin, nausea, headache, dizziness, fatigue, shortness of breath, rapid or shallow breathing, palpitation, anxiety, and confusion. Do not stop using medications without a doctor's advice.
RopivacaineRasburicase
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Taking rasburicase with Ropin 0.75% Injection 4ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Rasburicase and Ropin 0.75% Injection 4ml, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
RopivacaineDapsone
Severe
How does the drug interact with Ropin 0.75% Injection 4ml:
Taking Dapsone with Ropin 0.75% Injection 4ml can increase the risk of a condition called methemoglobinemia. (blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Ropin 0.75% Injection 4ml, you can take these medicines together if prescribed by a doctor. However, if you experience headache, dizziness, shortness of breath, or a rapid heartbeat contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

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Therapeutic Class

GENERAL ANESTHETICS

ROPIN 0.75% INJECTION 4ML Substitute

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Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Lakshmithulasi YarraguntaDoctor badge

Reviewed By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Last Updated

Jul 8, 2025 | 9:50 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ROPIN 0.75% INJECTION 4ML contains Ropivacaine Hydrochloride. It works by blocking the transmission of pain signals from the nerves to the brain.

ROPIN 0.75% INJECTION 4ML may affect your heart rhythm. Disturbances of the heart rhythm are very common. Your anaesthetist will quickly deal with any problems that arise during your operation.

Drug-Drug Interactions Checker List

  • AMINOSALICYLIC ACID
  • CHLOROQUINE
  • DAPSONE
  • IFOSFAMIDE
  • NITROGLYCERIN

Disease/Condition Glossary

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The tolerance level of pain might vary from person to person. Pain can be considered a good thing as it helps us know something is wrong in the body and helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach aches.

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