Rosave-Trio 20 Capsule belongs to a group of antihyperlipidemic and antiplatelets used to treat heart attack, myocardial infarction (blockage of the blood to muscles of the heart), angina (chest pain), and stroke. A heart attack happens when the blood flow to the heart is blocked. The blockage is most often a build-up of cholesterol, fat, and other substances, which form a plaque (semi-hard accumulation of substance from fluid) in the arteries that supply to the heart. Sometimes, a plaque can burst, forming a clot that blocks blood flow. Symptoms of a heart attack include chest pain, tightness in the chest, and pain in the neck, arm, or back.

Rosave-Trio 20 Capsule is a fixed-dose combination composed of three medicines: Rosuvastatin, Clopidogrel, and Aspirin. Rosuvastatin belongs to a group of drugs known as antihyperlipidemic. Rosuvastatin lowers the level of lipids. It blocks the ability of the body to produce bad cholesterol and improves the ability of the body to make good cholesterol. Clopidogrel and aspirin both belong to a group of drugs known as Antiplatelet. They work by preventing the blood from sticking together and decreasing the production of clots which is harmful to the body. Altogether Rosave-Trio 20 Capsule help to reduce the risk of heart attack, stroke and heart-related chest pain (angina).

Rosave-Trio 20 Capsule is available in the form of oral capsules. It usually takes one time a day with water or as prescribed by your doctor. Doses of the Rosave-Trio 20 Capsule will decide by your doctor. It should be taken after eating food (low lipid food). In some cases, Rosave-Trio 20 Capsule can cause side effects like Headache, Muscle pain, increased bleeding, stomach pain, Indigestion, Bruise (discolouration of the skin), bleeding in the nose, Weakness, Gastrointestinal bleeding, Diarrhea, and Nausea. Most of these side effects of Rosave-Trio 20 Capsule do not require medical attention and gradually resolve over time. But if bleeding persists longer, please consult your doctor.

If you are known to be allergic to Rosave-Trio 20 Capsule or any other medicines, please inform your doctor. Before taking Rosave-Trio 20 Capsule, let your doctor know if you have asthma, liver problems, kidney problems, ulcer, pregnancy, and breastfeeding. Please do not stop taking Rosave-Trio 20 Capsule on your own, as it may lead to the recurrence of symptoms or worsen the condition.

Rosave-Trio 20 Capsule belongs to a group of antihyperlipidemic and antiplatelets used to treat heart attack, myocardial infarction (blockage of the blood to muscles of the heart), angina (chest pain), and stroke. Rosave-Trio 20 Capsule is a fixed-dose combination composed of three medicines: Rosuvastatin, Clopidogrel, and aspirin. Rosuvastatin belongs to a group of drugs known as antihyperlipidemic. Rosuvastatin lowers the level of lipids. It blocks the ability of the body to produce bad cholesterol and improves the ability of the body to produce good cholesterol. It is used to lower cholesterol levels and treat heart and blood-related problems, heart attacks, and strokes. Clopidogrel and aspirin both belong to a group of drugs known as Antiplatelet. They work by preventing the blood from sticking together and decreasing the production of clots which is harmful to the body. It is used to treat chest pain and heart attack.

• Headache
• Muscle pain
• Increased tendency of bleeding
• Stomach pain
• Indigestion
• Bruise (discolouration of the skin)
• Bleeding in the nose
• Weakness
• Gastrointestinal bleeding
• Diarrhoea
• Nausea

Let your doctor know if are sensitive to rosuvastatin, clopidogrel or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Rosave-Trio 20 Capsule before any surgery is scheduled or any new medicine is taken. Patients with active liver disease should use Rosave-Trio 20 Capsule with caution. Safety and effectiveness of Rosave-Trio 20 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 16 years of age. Discontinuation of Rosave-Trio 20 Capsule may lead to the occurrence of cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Rosave-Trio 20 Capsule. Rosave-Trio 20 Capsule may reduce alertness, affect your vision, or make you feel dizzy and sleepy. If these symptoms occur, do not drive.

Drug-Drug Interactions: Care should be exercised when Rosave-Trio 20 Capsule is administered in combination with anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole), blood thinners (warfarin, heparin), anti-arthritis drug (colchicine), heart-related medicine (digoxin), and immune system affecting drug (cyclosporine).

Drug-Food Interactions: Alcoholic beverages and grapefruit or its juice intake should be avoided with Rosave-Trio 20 Capsule as it may interact with Rosave-Trio 20 Capsule to produce unpleasant side effects like muscle problems and bleeding disorder.

Drug-Disease Interactions: Rosave-Trio 20 Capsule should not be given to the patients with ulcers, erectile dysfunction (inability to get an enlarged penis), liver disease, kidney problems, purpura (blood leakage under the skin), and muscle problems or musculoskeletal problems (fibromyalgia).

• RITONAVIR
• LOPINAVIR
• ATAZANAVIR
• INDINAVIR
• ITRACONAZOLE
• WARFARIN
• HEPARIN
• COLCHICINE
• DIGOXIN
• CYCLOSPORINE

• Follow a cholesterol-lowering diet.
• Consume low salt and a low-fat diet.
• Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
• Limit salt and sugar intake.
• Avoid smoking and alcohol consumption.
• Choose healthy fats and cut down on trans fat.
• Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
• Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Myocardial infarction/Heart attack: Myocardial infarction occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form plaque in the arteries that feed the heart (coronary arteries). Heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.