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Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

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About Rozat CV Capsule

Rozat CV Capsule is a combination drug composed of a blood-thinning agent and cholesterol-lowering agent, primarily used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our body. A heart attack is a condition in which your coronary arteries (blood vessel supplying blood and oxygen to the heart) becomes blocked due to build-up of fats (plaque) including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Rozat CV Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Rozat CV Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina).

Take Rozat CV Capsule exactly as directed by your doctor. The dose and duration of Rozat CV Capsule may differ depending on the reason why you're taking it and your responses to treatment. In some cases, you may experience headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. Rozat CV Capsule is known to cause dizziness, so driving should be avoided. Most of these side effects of Rozat CV Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Rozat CV Capsule of your own. Suddenly stopping Rozat CV Capsule may worsen your condition and increase your risk of a future heart attack. Inform your doctor know if you are allergic to rosuvastatin, clopidogrel, or have any active liver disease (liver enzymes abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problem (myopathy, rhabdomyolysis). The patient should inform the doctor that they are taking Rozat CV Capsule before any surgery is scheduled or any new medicine is taken. Rosuvastatin present in Rozat CV Capsule is a pregnancy category X drug, so it should not be given to pregnant women. It may cause harm to the fetus if administered to pregnant or breastfeeding women.

Uses of Rozat CV Capsule

Hyperlipidemia (Increased cholesterol), Prevention of heart attack, Prevention of stroke

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Rozat CV Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rozat CV Capsule

  • Stomach bleeding
  • Gastrointestinal bleeding
  • Nose bleeding
  • Rash
  • Diarrhoea
  • Stomach ulcer
  • Muscle disease (myopathy, rhabdomyolysis)
  • Abdominal pain

Drug Warnings

Tell your doctor if you are allergic to rosuvastatin, clopidogrel, or any of its ingredients. If you have any active liver disease, active bleeding issues (like peptic ulcers, brain haemorrhage), pregnant, or plan to become pregnant or breastfeeding, do not take Rozat CV Capsule until prescribed. The patient should inform the doctor that they are taking Rozat CV Capsule before any surgery is scheduled or any new medicine is taken. Rosuvastatin present in Rozat CV Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to pregnant women. The risk of muscle problems might increase if Rozat CV Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole). Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. Rozat CV Capsule contains rosuvastatin, which can cause muscle problems like myopathy and rhabdomyolysis. Patients with active liver disease should use the Rozat CV Capsule with caution. Safety and effectiveness of Rozat CV Capsule have not been established, so its use should be avoided in paediatric patients less than ten years of age. Discontinuation of Rozat CV Capsule may lead to cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Rozat CV Capsule .

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
ClopidogrelSelexipag
Critical

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
How does the drug interact with Rozat CV Capsule:
Taking Rozat CV Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Rozat CV Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelSelexipag
Critical
How does the drug interact with Rozat CV Capsule:
When Selexipag and Rozat CV Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Rozat CV Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
RosuvastatinFenofibrate
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Rozat CV Capsule and Fenofibrate can increase the blood levels of Rozat CV Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rozat CV Capsule and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSaquinavir
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Saquinavir and Rozat CV Capsule can increase the blood levels of Rozat CV Capsule and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Rozat CV Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinDarunavir
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Rozat CV Capsule and Darunavir can increase the blood levels of Rozat CV Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rozat CV Capsule and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinNicotinamide
Severe
How does the drug interact with Rozat CV Capsule:
Coadministration of Nicotinamide with Rozat CV Capsule may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Nicotinamide with Rozat CV Capsule together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
RosuvastatinAmprenavir
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Rozat CV Capsule and amprenavir can increase the blood levels of Rozat CV Capsule and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rozat CV Capsule and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinRitonavir
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Ritonavir and Rozat CV Capsule can increase the blood levels of Rozat CV Capsule.

How to manage the interaction:
Co-administration of Ritonavir and Rozat CV Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinClopidogrel
Severe
How does the drug interact with Rozat CV Capsule:
Taking Rozat CV Capsule with clopidogrel can increase the blood levels of Rozat CV Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Rozat CV Capsule may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.
RosuvastatinGemfibrozil
Severe
How does the drug interact with Rozat CV Capsule:
Co-administration of Gemfibrozil and Rozat CV Capsule may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Rozat CV Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime effectively complement treatment with Rozat CV Capsule .
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish, and nuts contain too many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Rozat CV Capsule Substitute

Substitutes safety advice
  • Novastat CV 10 Capsule 15's

    by AYUR

    23.31per tablet
  • Rosuvas CV 10 Tablet 10's

    by Others

    18.00per tablet
  • Rosufit CV 10 Capsule 15's

    by AYUR

    23.94per tablet
  • Rozalet 10 Tablet 10's

    by AYUR

    18.00per tablet
  • Rosumac CV 10 Capsule 10's

    by Others

    22.50per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Rozat CV Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Rozat CV Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing and preventing the risk of heart attack, stroke and heart-related chest pain (angina).

Yes, Rozat CV Capsule contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, preventing heart attack and stroke.

No, Rozat CV Capsule contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Rozat CV Capsule .

If you accidentally take an overdose of Rozat CV Capsule , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, you should immediately go to the nearby clinic or hospital.

It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Do not drink grapefruit juice while taking Rozat CV Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Yes, prolonged use of Rozat CV Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Rozat CV Capsule , consult your doctor about this issue.

Drinking alcohol with Rozat CV Capsule may damage your liver and increase liver enzymes like transaminase. So, Rozat CV Capsule should be used with caution who consume alcohol and/or have a liver disease history.

Yes, taking Rozat CV Capsule can increase bleeding risk as it contains aspirin and clopidogrel, which belongs to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid bleeding. Before going through any surgical procedure, let your doctor know that you are taking the Rozat CV Capsule .

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Disease/Condition Glossary

Heart attack: Heart attack is when your coronary arteries (blood vessels supplying blood and oxygen to the heart) become blocked due to the build-up of fats (plaque), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, mainly for most heart attacks.

Stroke: Stroke occurs when the blood and oxygen supply to the brain is blocked or minimized. As a result, the brain tissue is deprived of getting oxygen and nutrients. After a few minutes, brain cells (neurons) start to die. A stroke is a medical emergency; immediate treatment is required; else can cause brain damage, coma or even death. 

Atherosclerosis: Atherosclerosis occurs when fats, cholesterol, and other substances known as plaque deposit on your artery walls that restrict blood flow. This plaque formation triggers blood clots, narrows the artery's size, and hardens it. This, in turn, can lead to various heart complications like atherosclerosis, heart attack, heart-related chest pain (angina), and stroke. However, it can also affect the body's arteries apart from the heart.

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