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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

RIVAROXABAN-15MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About RPIGAT 15 TABLETS

RPIGAT 15 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 15 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

RPIGAT 15 TABLETS contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take RPIGAT 15 TABLETS as prescribed. You are advised to take RPIGAT 15 TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of RPIGAT 15 TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to RPIGAT 15 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 15 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 15 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Uses of RPIGAT 15 TABLETS

Prevention of blood clot

Directions for Use

Take RPIGAT 15 TABLETS with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

RPIGAT 15 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 15 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. RPIGAT 15 TABLETS works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Rpigat 15 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Regularly exercise and have a balanced diet to maintain a healthy weight.
  • Eat lot of fruits and vegetables (minimum 5 servings/day).
  • Include vitamin K-rich foods for stable anticoagulation control.
  • Limit red and processed meats.
  • Avoid smoking and consumption of alcohol.
  • Changes in kidney function need immediate medical attention.
  • Always monitor your blood pressure and inform your healthcare team if there are any sudden changes.
  • Take medicines as prescribed and eat a balanced diet suggested by your dietician for healthy kidney function.
  • Physical activity and exercise must be included in your daily routine to have proper kidney functioning and to maintain a healthy weight.
  • Get enough sleep to reduce the stress levels that have a direct impact on your kidney functioning.
  • Avoid massaging the bruise, as this might worsen the damage to the injured tissue.
  • Resting the affected area helps prevent more injury and aids healing.
  • Place a cloth-wrapped ice pack or cold compress on the affected area for 10 to 15 minutes.
  • If the bruise is extensive, severe, or accompanied by other symptoms like warmth, redness, or swelling, get medical help.

Drug Warnings

RPIGAT 15 TABLETS should be used with caution in children. Prolonged use of RPIGAT 15 TABLETS may cause hair loss. Regular blood tests are recommended while taking RPIGAT 15 TABLETS to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to RPIGAT 15 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 15 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 15 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rpigat 15 mg Tablet:
Co-administration of Rpigat 15 mg Tablet together with Diclofenac may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Diclofenac and Rpigat 15 mg Tablet can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rpigat 15 mg Tablet:
Coadministration of Itraconazole and Rpigat 15 mg Tablet may significantly increase the blood levels of Rpigat 15 mg Tablet. This can increase the risk of serious bleeding complications.

How to manage the interaction:
Itraconazole and Rpigat 15 mg Tablet may interact, but if a doctor prescribes them, you can still use them. If you have dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, a severe headache, weakness, or any of these symptoms, consult a doctor. Never discontinue taking a medication without consulting a doctor.
How does the drug interact with Rpigat 15 mg Tablet:
Coadministration of carbamazepine and Rpigat 15 mg Tablet may reduce the blood levels of Rpigat 15 mg Tablet, which may reduce the treatment outcomes.

How to manage the interaction:
Although taking carbamazepine and Rpigat 15 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Rpigat 15 mg Tablet:
Taking Rpigat 15 mg Tablet with rifampicin can decrease the blood levels of Rpigat 15 mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Rpigat 15 mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rpigat 15 mg Tablet:
Co-administration of streptokinase and Rpigat 15 mg Tablet can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of streptokinase and Rpigat 15 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RivaroxabanRifapentine
Severe
How does the drug interact with Rpigat 15 mg Tablet:
The combined use of Rifapentine and Rpigat 15 mg Tablet may reduce the blood levels of Rpigat 15 mg Tablet, which may increase the risk or severity of bleeding problems.

How to manage the interaction:
Co-administration of Rifapentine and Rpigat 15 mg Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Rpigat 15 mg Tablet:
Co-administration of Rpigat 15 mg Tablet and Ibuprofen can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Rpigat 15 mg Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rpigat 15 mg Tablet:
Co-administration of Voriconazole and Rpigat 15 mg Tablet can increase the blood levels of Rpigat 15 mg Tablet and increase the risk of bleeding.

How to manage the interaction:
Co-administration of Voriconazole and Rpigat 15 mg Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience dizziness, red or black, tarry stools, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rpigat 15 mg Tablet:
Coadministration of Naproxen and Rpigat 15 mg Tablet may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Naproxen and Rpigat 15 mg Tablet, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
How does the drug interact with Rpigat 15 mg Tablet:
Co-administration of Aspirin and Rpigat 15 mg Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Although Co-administration of Aspirin and Rpigat 15 mg Tablet can lead to an interaction, they can be taken together if advised by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.
  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with RPIGAT 15 TABLETS and lead to unwanted side effects. Hence try to avoid these juices while taking RPIGAT 15 TABLETS .
  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to stop taking RPIGAT 15 TABLETS without consulting your doctor to worsen the condition. Therefore, take RPIGAT 15 TABLETS for as long as your doctor has prescribed it.

No, RPIGAT 15 TABLETS is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this RPIGAT 15 TABLETS , immediately consult your doctor and inform him about it.

RPIGAT 15 TABLETS has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes RPIGAT 15 TABLETS may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking RPIGAT 15 TABLETS along with other blood thinner medicines.

Avoid taking grapefruit and grapefruit juice while taking RPIGAT 15 TABLETS , and it contains compounds that slow down the metabolism of RPIGAT 15 TABLETS and increase the activity leading to bleeding.

It is not known that RPIGAT 15 TABLETS causes hair loss. Kindly contact your doctor.

RPIGAT 15 TABLETS is a type of medicine known as an anticoagulant. RPIGAT 15 TABLETS works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ENOXAPARIN
  • LOPINAVIR
  • RITONAVIR
  • ASPIRIN
  • IBUPROFEN
  • CARBAMAZEPINE
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN

Special Advise

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR, or international normalized ratio to analyze your blood clotting time.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling. Pulmonary embolism (blood clots in the lung) is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

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